Gabapentin, a Synthetic Analogue of Gamma Aminobutyric Acid, Reverses Systemic Acute Inflammation and Oxidative Stress in Mice

Inflammation

Volumn 37, Issue 5, 2014, Pages 1826-1836

  Dias, Jordana Maia ^a   de Brito, Tarcisio Vieira ^a   de Aguiar Magalhães, Diva ^a   da Silva Santos, Pammela Weryka ^a   Batista, Jalles Arruda ^a   do Nascimento Dias, Eulina Gabriela ^a   de Barros Fernandes, Heliana ^a   Damasceno, Samara Rodrigues Bonfim ^b   Silva, Renan O ^b   Aragão, Karoline S ^b   Souza, Marcellus H L P ^b   Medeiros, Jand Venes R ^a   Barbosa, André Luiz R ^a  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

anti inflammatory effect; anti oxidant action; gabapentin

Indexed keywords

4 AMINOBUTYRIC ACID; CYTOKINE; GABAPENTIN; GLUTATHIONE; INDOMETACIN; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; AMINE; ANTIINFLAMMATORY AGENT; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PAW EDEMA; PERITONEAL FLUID; PERITONEUM EXUDATE; PERITONITIS; ACUTE DISEASE; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; EDEMA; INFLAMMATION; METABOLISM; PHYSIOLOGY; RANDOMIZATION;

MUS;

ACUTE DISEASE; AMINES; ANIMALS; ANTI-INFLAMMATORY AGENTS; CYCLOHEXANECARBOXYLIC ACIDS; EDEMA; GAMMA-AMINOBUTYRIC ACID; INFLAMMATION; MALE; MICE; OXIDATIVE STRESS; RANDOM ALLOCATION;

EID: 84918814060     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9913-2     Document Type: Article

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