Maternal antiasthma simplified herbal medicine intervention therapy prevents airway inflammation and modulates pulmonary innate immune responses in young offspring mice

Annals of Allergy, Asthma and Immunology

Volumn 114, Issue 1, 2015, Pages 43-51.e1

  López Expósito, Iván ^a,b   Srivastava, Kamal D ^a   Birmingham, Neil ^a   Castillo, Alexandra ^a   Miller, Rachel L ^c   Li, Xiu Min ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF FOOD SCIENCE RESEARCH CIAL   (Spain)

^c Division of Pulmonary Allergy Critical Care Medicine Department of Medicine Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CXCL1 CHEMOKINE; DEXAMETHASONE; EOTAXIN; GAMMA INTERFERON; HERBACEOUS AGENT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; ASHMI HERBAL FORMULA; CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DOWN REGULATION; DRUG MECHANISM; EOSINOPHIL; FEMALE; GLYCYRRHIZA URALENSIS; HYPERPLASIA; IMMUNOMODULATION; INNATE IMMUNITY; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PROGENY; PROTEIN DETERMINATION; RESPIRATORY TRACT INFLAMMATION; SOPHORA FLAVESCENS; ADULT CHILD; ADVERSE EFFECTS; ANIMAL; ASTHMA; BAGG ALBINO MOUSE; BLOOD; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LUNG; MATERNAL EXPOSURE; METABOLISM; PASSIVE IMMUNIZATION; PNEUMONIA; PREGNANCY;

ADULT CHILDREN; ANIMALS; ANTIBODIES; ASTHMA; CHEMOKINE CCL11; CHEMOKINE CXCL1; CYTOKINES; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FEMALE; IMMUNITY, INNATE; IMMUNITY, MATERNALLY-ACQUIRED; LUNG; MALE; MATERNAL EXPOSURE; MICE; MICE, INBRED BALB C; PNEUMONIA; PREGNANCY;

EID: 84918792649     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/j.anai.2014.10.018     Document Type: Article

References (39)

1. Gern JE, Lemanske RF Jr, Busse WW. Early life origins of asthma. J Clin Invest. 1999;104:837-843.
2. Uthoff H, Spenner A, Reckelkamm W, et al. Critical role of preconceptional immunization for protective and nonpathological specific immunity in murine neonates. J Immunol. 2003;171:3485-3492.
3. Devereux G, Barker RN, Seaton A. Antenatal determinants of neonatal immune responses to allergens. Clin Exp Allergy. 2002;32:43-50.
4. Blumer N, Herz U, Wegmann M, Renz H. Prenatal lipopolysaccharideexposure prevents allergic sensitization and airway inflammation, but not airway responsiveness in a murine model of experimental asthma. Clin Exp Allergy. 2005;35:397-402.
5. Sears MR, Holdaway MD, Flannery EM, Herbison GP, Silva PA. Parental and neonatal risk factors for atopy, airway hyper-responsiveness, and asthma. Arch Dis Child. 1996;75:392-398.
6. Litonjua AA, Carey VJ, Burge HA, Weiss ST, Gold DR. Parental history and the risk for childhood asthma. Does mother confer more risk than father? Am J Respir Crit Care Med. 1998;158:176-181.
7. Latzin P, Frey U, Roiha HL, et al. Prospectively assessed incidence, severity, and determinants of respiratory symptoms in the first year of life. Pediatr Pulmonol. 2007;42:41-50.
8. Celedon JC, Litonjua AA, Ryan L, et al. Exposure to cat allergen, maternal history of asthma, and wheezing in first 5 years of life. Lancet. 2002;360: 781-782.
9. Kurukulaaratchy RJ, Waterhouse L, Matthews SM, Arshad SH. Are influences during pregnancy associated with wheezing phenotypes during the first decade of life? Acta Paediatr. 2005;94:553-558.
10. Kurukulaaratchy RJ, Matthews S, Waterhouse L, Arshad SH. Factors influencing symptom expression in children with bronchial hyperresponsiveness at 10 years of age. J Allergy Clin Immunol. 2003;112:311-316.
11. Hamada K, Suzaki Y, Goldman A, et al. Allergen-independent maternal transmission of asthma susceptibility. J Immunol. 2003;170:1683-1689.
12. Fedulov AV, Leme AS, Kobzik L. Duration of allergic susceptibility in maternal transmission of asthma risk. Am J Reprod Immunol. 2007;58:120-128.
13. Royer CM, Rudolph K, Barrett EG. The neonatal susceptibility window for inhalant allergen sensitization in the atopically predisposed canine asthma model. Immunology. 2013;138:361-369.
14. Expert Panel Report 3 [EPR-3]: guidelines for the diagnosis and management of asthmadsummary report 2007. J Allergy Clin Immunol. 2007;120: S94eS138.
15. Li XM. Traditional Chinese herbal remedies for asthma and food allergy [current perspectives]. J Allergy Clin Immunol. 2007;120:25-31.
16. Zhang T, Srivastava K, Wen MC, et al. Pharmacology and immunological actions of a herbal medicine ASHMI on allergic asthma. Phytother Res. 2010;24: 1047-1055.
17. Wen MC, Wei CH, Hu ZQ, et al. Efficacy and tolerability of anti-asthma herbal medicine intervention in adult patients with moderate-severe allergic asthma. J Allergy Clin Immunol. 2005;116:517-524.
18. Kelly-Pieper K, Patil SP, Busse P, et al. Safety and tolerability of an antiasthma herbal formula [ASHMI] in adult subjects with asthma: a randomized, doubleblinded, placebo-controlled, dose-escalation phase I study. J Altern Complement Med. 2009;15:735-743.
19. Kelly-Pieper K, Patil SP, Busse P, et al. Safety and tolerability of an antiasthma herbal formula [ASHMITM] in adult asthmatics: a randomized, doubleblinded, placebo-controlled, dose escalation phase I study. J Altern Complement Med. 2008.
20. Institute of Laboratory Animal Resources Commission of Life Sciences NRC. Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press; 1996.
21. Xiu SY. The Experimental Method of Pharmacology. Beijing: The People's Public Health Publisher; 1986.
22. Busse PJ, Zhang TF, Srivastava K, Schofield B, Li XM. Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice. Clin Exp Allergy. 2007;37: 1392-1403.
23. Levitt RC, Mitzner W. Expression of airway hyperreactivity to acetylcholine as a simple autosomal recessive trait in mice. FASEB J. 1988;2:2605-2608.
24. Li XM, Schofield BH, Wang QF, Kim KH, Huang SK. Induction of pulmonary allergic responses by antigen-specific Th2 cells. J Immunol. 1998;160: 1378-1384.
25. Kumar RK, Herbert C, Thomas PS, et al. Inhibition of inflammation and remodeling by roflumilast and dexamethasone in murine chronic asthma. J Pharmacol Exp Ther. 2003;307:349-355.
26. Martinez FD, Wright AL, Taussig LM, et al. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med. 1995;332: 133-138.
27. Lim RH, Kobzik L. Maternal transmission of asthma risk. Am J Reprod Immunol. 2009;61:1-10.
28. Roopenian DC, Christianson GJ, Sproule TJ. Human FcRn transgenic mice for pharmacokinetic evaluation of therapeutic antibodies. Methods Mol Biol. 2010;602:93-104.
29. Tincani A, Nuzzo M, Motta M, et al. Autoimmunity and pregnancy: autoantibodies and pregnancy in rheumatic diseases. Ann N Y Acad Sci. 2006;1069: 346-352.
30. Setiady YY, Samy ET, Tung KS. Maternal autoantibody triggers de novo T cell-mediated neonatal autoimmune disease. J Immunol. 2003;170: 4656-4664.
31. Lopez-Exposito I, Song Y, Jarvinen KM, Srivastava K, Li XM. Maternal peanut exposure during pregnancy and lactation reduces peanut allergy risk in offspring. J Allergy Clin Immunol. 2009;124:1039-1046.
32. Melkild I, Groeng EC, Leikvold RB, Granum B, Lovik M. Maternal allergen immunization during pregnancy in a mouse model reduces adult allergyrelated antibody responses in the offspring. Clin Exp Allergy. 2002;32: 1370-1376.
33. Matson AP, Thrall RS, Rafti E, Lingenheld EG, Puddington L. IgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring. Clin Mol Allergy. 2010;8:9.
34. Mosconi E, Rekima A, Seitz-Polski B, et al. Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. Mucosal Immunol. 2010;3:461-474.
35. Kobayashi Y. The role of chemokines in neutrophil biology. Front Biosci. 2008; 13:2400-2407.
36. Adar T, Shteingart S, Ben Ya'acov A, et al. From airway inflammation to inflammatory bowel disease: eotaxin-1, a key regulator of intestinal inflammation. Clin Immunol. 2014;153:199-208.
37. Srivastava KD, Dunkin D, Liu C, et al. Effect of antiasthma simplified herbal medicine intervention on neutrophil predominant airway inflammation in a ragweed sensitized murine asthma model. Ann Allergy Asthma Immunol. 2014;112:339-347.
38. Yang IV, Schwartz DA. Epigenetic mechanisms and the development of asthma. J Allergy Clin Immunol. 2012;130:1243-1255.
39. Wen X, Wu GD. Evidence for epigenetic mechanisms that silence both basal and immune-stimulated transcription of the IL-8 gene. J Immunol. 2001;166: 7290-7299.