MIF, a potential therapeutic target for rheumatoid arthritis?

Rheumatology International

Volumn 34, Issue 10, 2014, Pages 1481-1482

  Chen, Zhaolin ^a   Ma, Taotao ^a   Huang, Cheng ^a   Zhang, Lei ^a   Hu, Tingting ^a   Li, Jun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MACROPHAGE MIGRATION INHIBITION FACTOR;

ARTHRITIS, RHEUMATOID; GENETICS; HUMAN; METABOLISM;

ARTHRITIS, RHEUMATOID; HUMANS; MACROPHAGE MIGRATION-INHIBITORY FACTORS;

EID: 84918785249     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-013-2877-y     Document Type: Letter

References (11)

1. Herenius MM, Oliveira AS, Wijbrandts CA, Gerlag DM, Tak PP, Lebre MC (2013) Anti-TNF therapy reduces serum levels of chemerin in rheumatoid arthritis: a new mechanism by which anti-TNF might reduce inflammation. PLoS ONE 8:e57802
2. Kim HR, Kim KW, Jung HG, Yoon KS, Oh HJ, Cho ML, Lee SH (2011) Macrophage migration inhibitory factor enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthritis. Arthritis Res Ther 13:R43
3. Liu R, Xu N, Wang X, Shen L, Zhao G, Zhang H, Fan W (2012) Influence of MIF, CD40, and CD226 polymorphisms on risk of rheumatoid arthritis. Mol Biol Rep 39:6915–6922
4. Llamas-Covarrubias MA, Valle Y, Bucala R, Navarro-Hernandez RE, Palafox-Sanchez CA, Padilla-Gutierrez JR, Parra-Rojas I, Bernard-Medina AG, Reyes-Castillo Z, Munoz-Valle JF (2013) Macrophage migration inhibitory factor (MIF): genetic evidence for participation in early onset and early stage rheumatoid arthritis. Cytokine 61:759–765
5. Llamas-Covarrubias MA, Valle Y, Navarro-Hernandez RE, Guzman–Guzman IP, Ramirez-Duenas MG, Rangel-Villalobos H, Estrada-Chavez C, Munoz-Valle JF (2012) Serum levels of macrophage migration inhibitory factor are associated with rheumatoid arthritis course. Rheumatol Int 32:2307–2311
6. Meazza C, Travaglino P, Pignatti P, Magni-Manzoni S, Ravelli A, Martini A, De Benedetti F (2002) Macrophage migration inhibitory factor in patients with juvenile idiopathic arthritis. Arthritis Rheum 46:232–237
7. Onodera S, Kaneda K, Mizue Y, Koyama Y, Fujinaga M, Nishihira J (2000) Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis. J Biol Chem 275:444–450
8. Onodera S, Nishihira J, Iwabuchi K, Koyama Y, Yoshida K, Tanaka S, Minami A (2002) Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways. J Biol Chem 277:7865–7874
9. Onodera S, Tanji H, Suzuki K, Kaneda K, Mizue Y, Sagawa A, Nishihira J (1999) High expression of macrophage migration inhibitory factor in the synovial tissues of rheumatoid joints. Cytokine 11:163–167
10. Singh A, Leng L, Fan J, Gajda M, Brauer R, Fingerle-Rowson G, Bucala R, Illges H (2013) Macrophage-derived, macrophage migration inhibitory factor (MIF) is necessary to induce disease in the K/BxN serum-induced model of arthritis. Rheumatol Int 33:2301–2308
11. Wakabayashi K, Otsuka K, Sato M, Takahashi R, Odai T, Isozaki T, Yajima N, Miwa Y, Kasama T (2012) Elevated serum levels of macrophage migration inhibitory factor and their significant correlation with rheumatoid vasculitis disease activity. Mod Rheumatol 22:59–65