Effects of umbilical cord milking on the need for packed red blood cell transfusions and early neonatal hemodynamic adaptation in preterm infants born ≤ 1500 g: A prospective, randomized, controlled trial

Journal of Pediatric Hematology/Oncology

Volumn 36, Issue 8, 2014, Pages e493-e498

  Alan, Serdar ^a   Arsan, Saadet ^a   Okulu, Emel ^a   Akin, Ilke M ^b   Kilic, Atila ^a   Taskin, Salih ^a   Cetinkaya, Esra ^a   Erdeve, Omer ^a   Atasay, Begum ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b ISTANBUL MEDENIYET UNIVERSITY   (Turkey)

Author keywords

Anemia of prematurity; Placental transfusion; Preterm; Umbilical cord milking; Very low birth weight

Indexed keywords

ALBUMIN; AMINOGLYCOSIDE; AMPICILLIN; BILIRUBIN; HEMOGLOBIN; NITROGEN; POTASSIUM; UREA;

ALBUMIN BLOOD LEVEL; APGAR SCORE; ARTICLE; ARTIFICIAL VENTILATION; BIRTH WEIGHT; CHORIOAMNIONITIS; CLINICAL ARTICLE; CONTROLLED STUDY; ECLAMPSIA; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE TRANSFUSION; ESSENTIAL HYPERTENSION; FEMALE; GESTATIONAL AGE; HEMATOCRIT; HEMODYNAMIC PARAMETERS; HEMOGLOBIN BLOOD LEVEL; HUMAN; INFANT; LENGTH OF STAY; MALE; MEMBRANE RUPTURE; MORBIDITY; NEWBORN INTENSIVE CARE; NEWBORN SEPSIS; OBSTETRIC PROCEDURE; PHLEBOTOMY; POTASSIUM BLOOD LEVEL; PREECLAMPSIA; PREMATURE FETUS MEMBRANE RUPTURE; PREMATURITY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SCORE FOR NEONATAL ACUTE PHYSIOLOGY PERINATAL EXTENTION; SCORING SYSTEM; UMBILICAL CORD MILKING; UREA NITROGEN BLOOD LEVEL; VERY LOW BIRTH WEIGHT; ADAPTATION; ANEMIA, NEONATAL; BLOOD; HEMODYNAMICS; METABOLISM; NEWBORN; PLACENTA; PREGNANCY; PREGNANCY COMPLICATION; PROCEDURES; PROSPECTIVE STUDY; STATISTICAL MODEL; UMBILICAL CORD; VASCULARIZATION;

ADAPTATION, PHYSIOLOGICAL; ANEMIA, NEONATAL; ERYTHROCYTE TRANSFUSION; FEMALE; HEMODYNAMICS; HEMOGLOBINS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, VERY LOW BIRTH WEIGHT; INTENSIVE CARE, NEONATAL; LOGISTIC MODELS; MALE; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES; UMBILICAL CORD;

EID: 84918593134     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0000000000000143     Document Type: Article

References (20)

1. Bell EF, Strauss RG, Widness JA, et al. Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. Pediatrics. 2005;115:1685-1691.
2. Kirpalani H, Whyte RK, Andersen C, et al. The premature infants in needs of transfusions (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants. J Pediatr. 2006;149:301-307.
3. Brune T, Garritsen H, Witteler R, et al. Autologous placental blood transfusion for the therapy of anemic neonates. Biol Neonate. 2002;81:236-243.
4. Rabe H, Reynolds G, Diaz-Rossello J. A systematic review and meta-analysis of a brief delay in clamping the umbilical cord of preterm infants. Neonatology. 2008;93:138-144.
5. Hosono S, Mugishima H, Kitamura T, et al. Effect of hemoglobin on transfusion and neonatal adaptation in extremely low-birth weight infants. Pediatrics Int. 2008;50:306-311.
6. Linderkamp O. Placental transfusion: determinants and effects. Clin Perinatol. 1982;9:559-592.
7. Cunningham S, Symon AG, Elton RA, et al. Intra-arterial blood pressure reference ranges, death and morbidity in very low birthweight infants during the first seven days of life. Early Hum Dev. 1999;56:151-165.
8. Rabe H, Diaz-Rossello JL, Duley L, et al. Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes. Cochrane Database Syst Rev. 2012;8: CD003248.
9. Crowley M, Kirpalani H. A rational approach to red blood cell transfusion in the neonatal ICU. Curr Opin Pediatr. 2010;22:151-157.
10. Hosono S, Mugishima H, Fujita H, et al. Umbilical cord milking reduces the need for red cell transfusions and improves neonatal adaptation in infants born at less than 29 weeks' gestation: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed. 2008;93:14-19.
11. Hosono S, Mugishima H, Fujita H, et al. Blood pressure and urine output during the first 120 h of life in infants born at less than 29 weeks' gestation related to umbilical cord milking. Arch Dis Child Fetal Neonatal Ed. 2009;94:328-331.
12. March MI, Hacker MR, Parson AW, et al. The effects of umbilical cord milking in extremely preterm infants: randomized controlled trial. J Perinatol. 2013;33:763-767.
13. Papile LA, Burstein J, Burstein R, et al. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1500 g. J Pediatr. 1978;92:529-534.
14. Bell MJ, Ternberg JL, Feigin RD, et al. Neonatal necrotizing enterocolitis. Therapeutic decision based upon clinical staging. An Surg. 1978;187:1-7.
15. Committee for the classification of retinopathy of prematurity. An international classification of retinopathy of prematurity. Arch Ophthalmol. 1984;102:1130-1135.
16. Richardson DK, Corcoran JD, Escobar GJ, et al. SNAP-II, SNAPPE-II: simplified newborn illness severity and mortality risk scores. J Pediatr. 2001;138:92-100.
17. Altas B, Arsan S, Okulu E, et al. Evaluation of the Efficacy and Safety of Autologous Cord Blood Transfusions in Very Low Birth Weight Premature Newborns. Copenhagen, Denmark: The 3rd Congress of the European Academy of Paediatric Societies, October 23-26; 2010.
18. Rabe H, Jewison A, Alvarez RF, et al. Brighton Perinatal Study Group. Milking compared with delayed cord clamping to increase placental transfusion in preterm neonates: a randomized controlled trial. Obstet Gynecol. 2011;117:205-211.
19. Christensen RD, Baer VL, Gerday E, et al. Whole-blood viscosity in the neonate: effects of gestational age, hematocrit, mean corpuscular volume and umbilical cord milking. J Perinatol. 2014;34:16-21.
20. Takami T, Suganami Y, Sunohara D, et al. Umbilical cord milking stabilizes cerebral oxygenation and perfusion in infants born before 29 weeks of gestation. J Pediatr. 2012;161:742-747.