Single-dose systemic acetaminophen to prevent postoperative pain: A meta-analysis of randomized controlled trials

Clinical Journal of Pain

Volumn 31, Issue 1, 2015, Pages 86-93

  De Oliveira, Gildasio S ^a   Castro Alves, Lucas J ^a   McCarthy, Robert J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

acetaminophen; pain; preventive; surgery

Indexed keywords

MORPHINE; OPIATE; PARACETAMOL; PLACEBO; ANALGESIC AGENT;

ABSENCE OF SIDE EFFECTS; ANALGESIC ACTIVITY; CLINICAL TRIAL; DRUG EFFECT; HUMAN; META ANALYSIS; NUMBERS NEEDED TO TREAT; PAIN; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PRURITUS; REVIEW; SINGLE DRUG DOSE; SYSTEMATIC REVIEW; TREATMENT OUTCOME; BIBLIOGRAPHIC DATABASE; MOVEMENT (PHYSIOLOGY); PAIN, POSTOPERATIVE; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REST; STATISTICS AND NUMERICAL DATA; TIME;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; DATABASES, BIBLIOGRAPHIC; HUMANS; MOVEMENT; PAIN, POSTOPERATIVE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REST; TIME FACTORS; TREATMENT OUTCOME;

EID: 84918564239     PISSN: 07498047     EISSN: 15365409     Source Type: Journal    
DOI: 10.1097/AJP.0000000000000081     Document Type: Review

References (60)

1. Kim SY, Kim JM, Lee JH, et al. Efficacy of intraoperative dexmedetomidine infusion on emergence agitation and quality of recovery after nasal surgery. Br J Anaesth. 2013;111: 222-228.
2. De Oliveira GS Jr, Fitzgerald P, Streicher LF, et al. Systemic lidocaine to improve postoperative quality of recovery after ambulatory laparoscopic surgery. Anesth Analg. 2012;115: 262-267.
3. Gornall BF, Myles PS, Smith CL, et al. Measurement of quality of recovery using the QoR-40: a quantitative systematic review. Br J Anaesth. 2013;111:161-169.
4. Barreveld A, Witte J, Chahal H, et al. Preventive analgesia by local anesthetics: the reduction of postoperative pain by peripheral nerve blocks and intravenous drugs. Anesth Analg. 2013;116:1141-1161.
5. RichebéP, Rivat C, Liu SS. Perioperative or postoperative nerve block for preventive analgesia: should we care about the timing of our regional anesthesia? Anesth Analg. 2013;116: 969-970.
6. De Oliveira GS Jr, Agarwal D, Benzon HT. Perioperative single dose ketorolac to prevent postoperative pain: a metaanalysis of randomized trials. Anesth Analg. 2012;114:424-433.
7. White PF, Raeder J, Kehlet H. Ketorolac: its role as part of a multimodal analgesic regimen. Anesth Analg. 2012;114: 250-254.
8. Waldron NH, Jones CA, Gan TJ, et al. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. Br J Anaesth. 2013; 110:191-200.
9. Short J, Downey K, Bernstein P, et al. A single preoperative dose of gabapentin does not improve postcesarean delivery pain management: a randomized, double-blind, placebo-controlled dose-finding trial. Anesth Analg. 2012;115:1336-1342.
10. Bornemann-Cimenti H, Lederer AJ, Wejbora M, et al. Preoperative pregabalin administration significantly reduces postoperative opioid consumption and mechanical hyperalgesia after transperitoneal nephrectomy. Br J Anaesth. 2012;108:845-849.
11. Tzortzopoulou A, McNicol ED, Cepeda MS, et al. Single dose intravenous propacetamol or intravenous paracetamol for postoperative pain. Cochrane Database Syst Rev. 2011; 10:CD007126. doi: 10.1002/14651858.CD007126.pub2.
12. McNicol ED, Tzortzopoulou A, Cepeda MS, et al. Single-dose intravenous paracetamol or propacetamol for prevention or treatment of postoperative pain: a systematic review and metaanalysis. Br J Anaesth. 2011;106:764-775.
13. Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol. 2009;62:e1-e34.
14. Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996;17:1-12.
15. Macintyre PE, Ready LB. Pharmacology of opioids. In: Macintyre PE, Ready LB, eds. Acute Pain Management-A Practical Guide. 2nd ed. London: W.B. Saunders; 2001:15-49.
16. Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol. 2005;5:13.
17. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177-188.
18. Egger M, Davey Smith G, Schneider M, et al. Bias in metaanalysis detected by a simple, graphical test. BM. 1997; 315:629-634.
19. De Oliveira GS Jr, Chang R, Kendall MC, et al. Publication bias in the anesthesiology literature. Anesth Analg. 2012; 114:1042-1048.
20. Rosenthal R. The file drawer problem and tolerance for null results". Psychol Bull. 1979;86:638-641.
21. Jones VM. Acetaminophen injection: a review of clinical information. J Pain Palliat Care Pharmacother. 2011;25: 340-349.
22. de Oliveira GS Jr, Balliu B, Nader A, et al. Dose-ranging effects of intrathecal epinephrine on anesthesia/analgesia: a meta-analysis and metaregression of randomized controlled trials. Reg Anesth Pain Med. 2012;37:423-432.
23. Brett CN, Barnett SG, Pearson J. Postoperative plasma paracetamol levels following oral or intravenous paracetamol administration: a double-blind randomised controlled trial. Anaesth Intensive Care. 2012;40:166-171.
24. Yadeau JT, Paroli L, Kahn RL, et al. Addition of pregabalin to multimodal analgesic therapy following ankle surgery: a randomized double-blind, placebo-controlled trial. Reg Anesth Pain Med. 2012;37:302-307.
25. Allegaert K, Kulo A, Verbesselt R, et al. The pharmacokinetics of a high intravenous dose of paracetamol after caesarean delivery: the effect of gestational age. Eur J Anaesthesiol. 2012;29:484-488.
26. YaDeau JT, Tedore T, Goytizolo EA, et al. Lumbar plexus blockade reduces pain after hip arthroscopy: a prospective randomized controlled trial. Anesth Analg. 2012;115:968-972.
27. Avellaneda C, Gómez A, Martos F, et al. The effect of a single intravenous dose of metamizol 2 g, ketorolac 30 mg and propacetamol 1 g on haemodynamic parameters and postoperative pain after heart surgery. Eur J Anaesthesiol. 2000; 17:85-90.
28. Lunn TH, Andersen L, Kristensen BB. Effect of high-dose preoperative methylprednisolone on recovery after total hip arthroplasty: a randomized, double-blind, placebo-controlled trial. Br J Anaesth. 2013;110:66-73.
29. van der Vijver RJ, van Laarhoven CJ, Lomme RM, et al. Paracetamol does not compromise early wound repair in the intestine or abdominal wall in the rat. Anesth Analg. 2012;115:1451-1456.
30. Loader J, Brooks T. Paracetamol or metronidazole? Br J Anaesth. 2013;111:301-302.
31. Zahoor A, Mateger M, Ahmad N. Is previous cholecystectomy a contraindication to paracetamol/codeine premedication? Eur J Anaesthesiol. 2013;30:131-132.
32. Mohammed BS, Engelhardt T, Cameron GA. Population pharmacokinetics of single-dose intravenous paracetamol in children. Br J Anaesth. 2012;108:823-829.
33. Cok OY, Eker HE, Pelit A, et al. The effect of paracetamol on postoperative nausea and vomiting during the first 24 h after strabismus surgery: a prospective, randomised, doubleblind study. Eur J Anaesthesiol. 2011;28:836-841.
34. Dejonckheere M, Desjeux L, Deneu S, et al. Intravenous tramadol compared to propacetamol for postoperative analgesia following thyroidectomy. Acta Anaesthesiol Belg. 2001;52:29-33.
35. Fenlon S, Collyer J, Giles J, et al. Oral vs. intravenous paracetamol for lower third molar extractions under generalanaesthesia: is oral administration inferior? Br J Anaesth. 2013;110:432-437.
36. Tunali Y, Akcil EF, Dilmen OK, et al. Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. J Neurosurg Anesthesiol. 2013;25:143-147.
37. Brodner G, Gogarten W, Van Aken H, et al. Efficacy of intravenous paracetamol compared to dipyrone and parecoxib for postoperative pain management after minor-to-intermediate surgery: a randomised, double-blind trial. Eur J Anaesthesiol. 2011;28:125-132.
38. Ohnesorge H, Bein B, Hanss R, et al. Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial. Eur J Anaesthesiol. 2009;26:648-653.
39. Alhashemi JA, Alotaibi QA, Mashaat MS, et al. Intravenous acetaminophen vs oral ibuprofen in combination with morphine PCIA after cesarean delivery. Can J Anaesth. 2006; 53:1200-1206.
40. Hiller A, Helenius I, Nurmi E. Acetaminophen improves analgesia but does not reduce opioid requirement after major spine surgery in children and adolescents. Spine (Phila Pa 1976). 2012;37:E1225-E1231.
41. Hynes D, McCarroll M, Hiesse-Provost O. Analgesic efficacy of parenteral paracetamol (propacetamol) and diclofenac in post-operative orthopaedic pain. Acta Anaesthesiol Scand. 2006;50:374-381.
42. Khalili G, Janghorbani M, Saryazdi H, et al. Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery. J Clin Anesth. 2013; 25:188-192.
43. Olonisakin RP, Amanor-Boadu SD, Akinyemi AO. Morphinesparing effect of intravenous paracetamol for post operative pain management following gynaecological surgery. Afr J Med Med Sci. 2012;41:429-436.
44. Arslan M, Cicek R, Celep B, et al. Comparison of the analgesic effects of intravenous paracetamol and lornoxicam in postoperative pain following thyroidectomies. Agri. 2011;23: 160-166.
45. Moon YE, Lee YK, Lee J, et al. The effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy. Arch Gynecol Obstet. 2011;284: 1455-1460.
46. Sen H, Kulahci Y, Bicerer E, et al. The analgesic effect of paracetamol when added to lidocaine for intravenous regional anesthesia. Anesth Analg. 2009;109:1327-1330.
47. Salihoglu Z, Yildirim M, Demiroluk S, et al. Evaluation of intravenous paracetamol administration on postoperative pain and recovery characteristics in patients undergoing laparoscopic cholecystectomy. Surg Laparosc Endosc Percutan Tech. 2009;19:321-323.
48. Salonen A, Silvola J, Kokki H. Does 1 or 2 g paracetamol added to ketoprofen enhance analgesia in adult tonsillectomy patients? Acta Anaesthesiol Scand. 2009;53:1200-1206.
49. Arici S, Gurbet A, Türker G, et al. Preemptive analgesic effects of intravenous paracetamol in total abdominal hysterectomy. Agri. 2009;21:54-61.
50. Api O, Unal O, Ugurel V, et al. Analgesic efficacy of intravenous paracetamol for outpatient fractional curettage: a randomised, controlled trial. Int J Clin Pract. 2009;63: 105-111.
51. Silvanto M, Munsterhjelm E, Savolainen S, et al. Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia. Acta Anaesthesiol Scand. 2007;51:1147-1154.
52. Hahn TW, Mogensen T, Lund C, et al. Analgesic effect of i.v. paracetamol: possible ceiling effect of paracetamol in postoperative pain. Acta Anaesthesiol Scand. 2003;47:138-145.
53. Joshi GP, Ahmad S, Riad W, et al. Selection of obese patients undergoing ambulatory surgery: a systematic review of the literature. Anesth Analg. 2013;5:1082-1091.
54. Bergmann I, Göhner A, Crozier TA, et al. Surgical pleth indexguided remifentanil administration reduces remifentanil and propofol consumption and shortens recovery times in outpatient anaesthesia. Br J Anaesth. 2013;110:622-628.
55. De Oliveira GS Jr, Castro-Alves LJ, Ahmad S, et al. Dexamethasone to prevent postoperative nausea and vomiting: an updated meta-analysis of randomized controlled trials. Anesth Analg. 2013;116:58-74.
56. De Oliveira GS Jr, Castro-Alves LJ, Chang R, et al. Systemic metoclopramide to prevent postoperative nausea and vomiting: a meta-analysis without Fujiis studies. Br J Anaesth. 2012;109:688-697.
57. Harsten A, Kehlet H, Toksvig-Larsen S. Recovery after total intravenous general anaesthesia or spinal anaesthesia for total knee arthroplasty: a randomized trial. Br J Anaesth. 2013;111:391-399.
58. Fawcett WJ,Mythen MG, Scott MJ. Enhanced recovery: more than just reducing length of stay? Br J Anaesth. 2012;109: 671-674.
59. Tzimas P, Prout J, Papadopoulos G, et al. Epidural anaesthesia and analgesia for liver resection. Anaesthesia. 2013; 68:628-635.
60. Apfel CC, Turan A, Souza K, et al. Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis. Pain. 2013;154:677-689.