메뉴 건너뛰기




Volumn 71, Issue 2, 2015, Pages 154-160

The effect of nitrogen containing bisphosphonates, zoledronate and alendronate, on the production of pro-angiogenic factors by osteoblastic cells

Author keywords

Angiogenesis; Angiopoietin 1; Bisphosphonates; Osteoblasts; VEGF

Indexed keywords

ALENDRONIC ACID; ANGIOGENIC FACTOR; ANGIOPOIETIN 1; BISPHOSPHONIC ACID DERIVATIVE; CALCITRIOL; CALCIUM; NITROGEN; VASCULOTROPIN; VITAMIN D; ZOLEDRONIC ACID; BONE DENSITY CONSERVATION AGENT; CULTURE MEDIUM; IMIDAZOLE DERIVATIVE; PEPTIDE FRAGMENT; PROCOLLAGEN; PROCOLLAGEN TYPE I N-TERMINAL PEPTIDE; VASCULOTROPIN A;

EID: 84918540158     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2014.10.025     Document Type: Article
Times cited : (52)

References (51)
  • 1
    • 78651082309 scopus 로고    scopus 로고
    • Concise review: insights from normal bone remodeling and stem cell-based therapies for bone repair
    • Khosla S., Westendorf J.J., Modder U.I. Concise review: insights from normal bone remodeling and stem cell-based therapies for bone repair. Stem Cells 2010, 28(12):2124-2128.
    • (2010) Stem Cells , vol.28 , Issue.12 , pp. 2124-2128
    • Khosla, S.1    Westendorf, J.J.2    Modder, U.I.3
  • 2
    • 0034874481 scopus 로고    scopus 로고
    • Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers
    • Hauge E.M., Qvesel D., Eriksen E.F., Mosekilde L., Melsen F. Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers. J Bone Miner Res 2001, 16(9):1575-1582.
    • (2001) J Bone Miner Res , vol.16 , Issue.9 , pp. 1575-1582
    • Hauge, E.M.1    Qvesel, D.2    Eriksen, E.F.3    Mosekilde, L.4    Melsen, F.5
  • 5
    • 67651112022 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates osteoblast survival - evidence for an autocrine feedback mechanism
    • Street J., Lenehan B. Vascular endothelial growth factor regulates osteoblast survival - evidence for an autocrine feedback mechanism. J Orthop Surg Res 2009, 4:19.
    • (2009) J Orthop Surg Res , vol.4 , pp. 19
    • Street, J.1    Lenehan, B.2
  • 6
    • 0035145620 scopus 로고    scopus 로고
    • Tie2 ligands angiopoietin-1 and angiopoietin-2 are coexpressed with vascular endothelial cell growth factor in growing human bone
    • Horner A., Bord S., Kelsall A.W., Coleman N., Compston J.E. Tie2 ligands angiopoietin-1 and angiopoietin-2 are coexpressed with vascular endothelial cell growth factor in growing human bone. Bone 2001, 28(1):65-71.
    • (2001) Bone , vol.28 , Issue.1 , pp. 65-71
    • Horner, A.1    Bord, S.2    Kelsall, A.W.3    Coleman, N.4    Compston, J.E.5
  • 7
    • 0032749339 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 modulates the expression of vascular endothelial growth factor by osteoblasts
    • C628-37
    • Saadeh P.B., Mehrara B.J., Steinbrech D.S., Dudziak M.E., Greenwald J.A., Luchs J.S., et al. Transforming growth factor-beta1 modulates the expression of vascular endothelial growth factor by osteoblasts. Am J Physiol 1999, 277(4 Pt 1):C628-37.
    • (1999) Am J Physiol , vol.277 , Issue.4
    • Saadeh, P.B.1    Mehrara, B.J.2    Steinbrech, D.S.3    Dudziak, M.E.4    Greenwald, J.A.5    Luchs, J.S.6
  • 9
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan D. Signaling vascular morphogenesis and maintenance. Science 1997, 277(5322):48-50.
    • (1997) Science , vol.277 , Issue.5322 , pp. 48-50
    • Hanahan, D.1
  • 10
    • 41049093982 scopus 로고    scopus 로고
    • Wnt/Frizzled signaling in angiogenesis
    • Zerlin M., Julius M.A., Kitajewski J. Wnt/Frizzled signaling in angiogenesis. Angiogenesis 2008, 11(1):63-69.
    • (2008) Angiogenesis , vol.11 , Issue.1 , pp. 63-69
    • Zerlin, M.1    Julius, M.A.2    Kitajewski, J.3
  • 11
    • 1542782290 scopus 로고    scopus 로고
    • RANKL and vascular endothelial growth factor (VEGF) induce osteoclast chemotaxis through an ERK1/2-dependent mechanism
    • Henriksen K., Karsdal M., Delaisse J.M., Engsig M.T. RANKL and vascular endothelial growth factor (VEGF) induce osteoclast chemotaxis through an ERK1/2-dependent mechanism. J Biol Chem 2003, 278(49):48745-48753.
    • (2003) J Biol Chem , vol.278 , Issue.49 , pp. 48745-48753
    • Henriksen, K.1    Karsdal, M.2    Delaisse, J.M.3    Engsig, M.T.4
  • 13
    • 84866074318 scopus 로고    scopus 로고
    • Clinical role of bisphosphonate therapy
    • Hampson G., Fogelman I. Clinical role of bisphosphonate therapy. Int J Womens Health 2012, 4:455-469.
    • (2012) Int J Womens Health , vol.4 , pp. 455-469
    • Hampson, G.1    Fogelman, I.2
  • 14
    • 0031977199 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
    • Luckman S.P., Hughes D.E., Coxon F.P., Graham R., Russell G., Rogers M.J. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res 1998, 13(4):581-589.
    • (1998) J Bone Miner Res , vol.13 , Issue.4 , pp. 581-589
    • Luckman, S.P.1    Hughes, D.E.2    Coxon, F.P.3    Graham, R.4    Russell, G.5    Rogers, M.J.6
  • 16
    • 79958764505 scopus 로고    scopus 로고
    • Novel actions of bisphosphonates in bone: preservation of osteoblast and osteocyte viability
    • Bellido T., Plotkin L.I. Novel actions of bisphosphonates in bone: preservation of osteoblast and osteocyte viability. Bone 2011, 49(1):50-55.
    • (2011) Bone , vol.49 , Issue.1 , pp. 50-55
    • Bellido, T.1    Plotkin, L.I.2
  • 17
    • 41049084067 scopus 로고    scopus 로고
    • Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro
    • Idris A.I., Rojas J., Greig I.R., Van't Hof R.J., Ralston S.H. Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro. Calcif Tissue Int 2008, 82(3):191-201.
    • (2008) Calcif Tissue Int , vol.82 , Issue.3 , pp. 191-201
    • Idris, A.I.1    Rojas, J.2    Greig, I.R.3    Van't Hof, R.J.4    Ralston, S.H.5
  • 18
    • 84155171114 scopus 로고    scopus 로고
    • Pathophysiology of atypical femoral fractures and osteonecrosis of the jaw
    • Compston J. Pathophysiology of atypical femoral fractures and osteonecrosis of the jaw. Osteoporos Int 2011, 22(12):2951-2961.
    • (2011) Osteoporos Int , vol.22 , Issue.12 , pp. 2951-2961
    • Compston, J.1
  • 19
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research
    • Khosla S., Burr D., Cauley J., Dempster D.W., Ebeling P.R., Felsenberg D., et al. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2007, 22(10):1479-1491.
    • (2007) J Bone Miner Res , vol.22 , Issue.10 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3    Dempster, D.W.4    Ebeling, P.R.5    Felsenberg, D.6
  • 20
    • 79551517591 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw: an overview
    • Ruggiero S.L. Bisphosphonate-related osteonecrosis of the jaw: an overview. Ann N Y Acad Sci 2011, 1218:38-46.
    • (2011) Ann N Y Acad Sci , vol.1218 , pp. 38-46
    • Ruggiero, S.L.1
  • 21
    • 84918525095 scopus 로고    scopus 로고
    • Atypical femoral fractures: retrospective radiological study of 319 femoral fractures and presentation of clinical cases
    • Bottai V., Giannotti S., Dell'osso G., De Paola G., Menconi A., Falossi F., et al. Atypical femoral fractures: retrospective radiological study of 319 femoral fractures and presentation of clinical cases. Osteoporos Int 2013.
    • (2013) Osteoporos Int
    • Bottai, V.1    Giannotti, S.2    Dell'osso, G.3    De Paola, G.4    Menconi, A.5    Falossi, F.6
  • 22
    • 10744227993 scopus 로고    scopus 로고
    • Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients
    • Santini D., Vincenzi B., Dicuonzo G., Avvisati G., Massacesi C., Battistoni F., et al. Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients. Clin Cancer Res 2003, 9(8):2893-2897.
    • (2003) Clin Cancer Res , vol.9 , Issue.8 , pp. 2893-2897
    • Santini, D.1    Vincenzi, B.2    Dicuonzo, G.3    Avvisati, G.4    Massacesi, C.5    Battistoni, F.6
  • 23
    • 79960285325 scopus 로고    scopus 로고
    • Differential impairment of vascularization and angiogenesis in bisphosphonate-associated osteonecrosis of the jaw-related mucoperiosteal tissue
    • Wehrhan F., Stockmann P., Nkenke E., Schlegel K.A., Guentsch A., Wehrhan T., et al. Differential impairment of vascularization and angiogenesis in bisphosphonate-associated osteonecrosis of the jaw-related mucoperiosteal tissue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011, 112(2):216-221.
    • (2011) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.112 , Issue.2 , pp. 216-221
    • Wehrhan, F.1    Stockmann, P.2    Nkenke, E.3    Schlegel, K.A.4    Guentsch, A.5    Wehrhan, T.6
  • 24
    • 73449089472 scopus 로고    scopus 로고
    • Bisphosphonates suppress insulin-like growth factor 1-induced angiogenesis via the HIF-1alpha/VEGF signaling pathways in human breast cancer cells
    • Tang X., Zhang Q., Shi S., Yen Y., Li X., Zhang Y., et al. Bisphosphonates suppress insulin-like growth factor 1-induced angiogenesis via the HIF-1alpha/VEGF signaling pathways in human breast cancer cells. Int J Cancer 2010, 126(1):90-103.
    • (2010) Int J Cancer , vol.126 , Issue.1 , pp. 90-103
    • Tang, X.1    Zhang, Q.2    Shi, S.3    Yen, Y.4    Li, X.5    Zhang, Y.6
  • 25
    • 72849142082 scopus 로고    scopus 로고
    • Cutting the limits of aminobisphosphonates: new strategies for the potentiation of their anti-tumour effects
    • Marra M., Abbruzzese A., Addeo R., Del Prete S., Tassone P., Tonini G., et al. Cutting the limits of aminobisphosphonates: new strategies for the potentiation of their anti-tumour effects. Curr Cancer Drug Targets 2009, 9(7):791-800.
    • (2009) Curr Cancer Drug Targets , vol.9 , Issue.7 , pp. 791-800
    • Marra, M.1    Abbruzzese, A.2    Addeo, R.3    Del Prete, S.4    Tassone, P.5    Tonini, G.6
  • 28
    • 0037291292 scopus 로고    scopus 로고
    • Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro
    • Reffitt D.M., Ogston N., Jugdaohsingh R., Cheung H.F., Evans B.A., Thompson R.P., et al. Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone 2003, 32(2):127-135.
    • (2003) Bone , vol.32 , Issue.2 , pp. 127-135
    • Reffitt, D.M.1    Ogston, N.2    Jugdaohsingh, R.3    Cheung, H.F.4    Evans, B.A.5    Thompson, R.P.6
  • 29
    • 0036803168 scopus 로고    scopus 로고
    • Dexamethasone and retinoic acid differentially regulate growth and differentiation in an immortalised human clonal bone marrow stromal cell line with osteoblastic characteristics
    • Ogston N., Harrison A.J., Cheung H.F., Ashton B.A., Hampson G. Dexamethasone and retinoic acid differentially regulate growth and differentiation in an immortalised human clonal bone marrow stromal cell line with osteoblastic characteristics. Steroids 2002, 67(11):895-906.
    • (2002) Steroids , vol.67 , Issue.11 , pp. 895-906
    • Ogston, N.1    Harrison, A.J.2    Cheung, H.F.3    Ashton, B.A.4    Hampson, G.5
  • 30
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 31
    • 0036093899 scopus 로고    scopus 로고
    • Pamidronate induces modifications of circulating angiogenetic factors in cancer patients
    • Santini D., Vincenzi B., Avvisati G., Dicuonzo G., Battistoni F., Gavasci M., et al. Pamidronate induces modifications of circulating angiogenetic factors in cancer patients. Clin Cancer Res 2002, 8(5):1080-1084.
    • (2002) Clin Cancer Res , vol.8 , Issue.5 , pp. 1080-1084
    • Santini, D.1    Vincenzi, B.2    Avvisati, G.3    Dicuonzo, G.4    Battistoni, F.5    Gavasci, M.6
  • 32
    • 79952667050 scopus 로고    scopus 로고
    • Anti-tumour and anti-angiogenetic effects of zoledronic acid on human non-small-cell lung cancer cell line
    • Di Salvatore M., Orlandi A., Bagala C., Quirino M., Cassano A., Astone A., et al. Anti-tumour and anti-angiogenetic effects of zoledronic acid on human non-small-cell lung cancer cell line. Cell Prolif 2011, 44(2):139-146.
    • (2011) Cell Prolif , vol.44 , Issue.2 , pp. 139-146
    • Di Salvatore, M.1    Orlandi, A.2    Bagala, C.3    Quirino, M.4    Cassano, A.5    Astone, A.6
  • 33
    • 42549137841 scopus 로고    scopus 로고
    • Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model
    • Soltau J., Zirrgiebel U., Esser N., Schachtele C., Totzke F., Unger C., et al. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model. Anticancer Res 2008, 28(2A):933-941.
    • (2008) Anticancer Res , vol.28 , Issue.2 A , pp. 933-941
    • Soltau, J.1    Zirrgiebel, U.2    Esser, N.3    Schachtele, C.4    Totzke, F.5    Unger, C.6
  • 34
    • 77957134474 scopus 로고    scopus 로고
    • Metronomic administration of zoledronic acid and taxotere combination in castration resistant prostate cancer patients: phase I ZANTE trial
    • Facchini G., Caraglia M., Morabito A., Marra M., Piccirillo M.C., Bochicchio A.M., et al. Metronomic administration of zoledronic acid and taxotere combination in castration resistant prostate cancer patients: phase I ZANTE trial. Cancer Biol Ther 2010, 10(6):543-548.
    • (2010) Cancer Biol Ther , vol.10 , Issue.6 , pp. 543-548
    • Facchini, G.1    Caraglia, M.2    Morabito, A.3    Marra, M.4    Piccirillo, M.C.5    Bochicchio, A.M.6
  • 35
    • 84869490626 scopus 로고    scopus 로고
    • The cytotoxic effects of three different bisphosphonates in-vitro on human gingival fibroblasts, osteoblasts and osteogenic sarcoma cells
    • e229-35
    • Acil Y., Moller B., Niehoff P., Rachko K., Gassling V., Wiltfang J., et al. The cytotoxic effects of three different bisphosphonates in-vitro on human gingival fibroblasts, osteoblasts and osteogenic sarcoma cells. J Craniomaxillofac Surg 2012, 40(8):e229-35.
    • (2012) J Craniomaxillofac Surg , vol.40 , Issue.8
    • Acil, Y.1    Moller, B.2    Niehoff, P.3    Rachko, K.4    Gassling, V.5    Wiltfang, J.6
  • 36
    • 84862815521 scopus 로고    scopus 로고
    • Effects of alendronate on human osteoblast-like MG63 cells and matrix metalloproteinases
    • Sun J., Song F., Zhang W., Sexton B.E., Windsor L.J. Effects of alendronate on human osteoblast-like MG63 cells and matrix metalloproteinases. Arch Oral Biol 2012, 57(6):728-736.
    • (2012) Arch Oral Biol , vol.57 , Issue.6 , pp. 728-736
    • Sun, J.1    Song, F.2    Zhang, W.3    Sexton, B.E.4    Windsor, L.J.5
  • 37
    • 0026320852 scopus 로고
    • Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure
    • Sato M., Grasser W., Endo N., Akins R., Simmons H., Thompson D.D., et al. Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. J Clin Invest 1991, 88(6):2095-2105.
    • (1991) J Clin Invest , vol.88 , Issue.6 , pp. 2095-2105
    • Sato, M.1    Grasser, W.2    Endo, N.3    Akins, R.4    Simmons, H.5    Thompson, D.D.6
  • 39
    • 57549103742 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw: who gets it, and why?
    • Reid I.R. Osteonecrosis of the jaw: who gets it, and why?. Bone 2009, 44(1):4-10.
    • (2009) Bone , vol.44 , Issue.1 , pp. 4-10
    • Reid, I.R.1
  • 40
    • 70349412921 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation?
    • Lesclous P., Abi Najm S., Carrel J.P., Baroukh B., Lombardi T., Willi J.P., et al. Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation?. Bone 2009, 45(5):843-852.
    • (2009) Bone , vol.45 , Issue.5 , pp. 843-852
    • Lesclous, P.1    Abi Najm, S.2    Carrel, J.P.3    Baroukh, B.4    Lombardi, T.5    Willi, J.P.6
  • 41
    • 11144357258 scopus 로고    scopus 로고
    • ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation
    • Brown C., Gaspar J., Pettit A., Lee R., Gu X., Wang H., et al. ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. J Biol Chem 2004, 279(13):12794-12803.
    • (2004) J Biol Chem , vol.279 , Issue.13 , pp. 12794-12803
    • Brown, C.1    Gaspar, J.2    Pettit, A.3    Lee, R.4    Gu, X.5    Wang, H.6
  • 42
    • 79953741598 scopus 로고    scopus 로고
    • Anatomic site variability in rat skeletal uptake and desorption of fluorescently labeled bisphosphonate
    • Wen D., Qing L., Harrison G., Golub E., Akintoye S.O. Anatomic site variability in rat skeletal uptake and desorption of fluorescently labeled bisphosphonate. Oral Dis 2011, 17(4):427-432.
    • (2011) Oral Dis , vol.17 , Issue.4 , pp. 427-432
    • Wen, D.1    Qing, L.2    Harrison, G.3    Golub, E.4    Akintoye, S.O.5
  • 43
    • 79952989968 scopus 로고    scopus 로고
    • Dose-dependent differential effects of risedronate on gene expression in osteoblasts
    • Wang J., Stern P.H. Dose-dependent differential effects of risedronate on gene expression in osteoblasts. Biochem Pharmacol 2011, 81(8):1036-1042.
    • (2011) Biochem Pharmacol , vol.81 , Issue.8 , pp. 1036-1042
    • Wang, J.1    Stern, P.H.2
  • 44
    • 84891559851 scopus 로고    scopus 로고
    • Osteocyte-induced angiogenesis via VEGF-MAPK-dependent pathways in endothelial cells
    • Prasadam I., Zhou Y., Du Z., Chen J., Crawford R., Xiao Y. Osteocyte-induced angiogenesis via VEGF-MAPK-dependent pathways in endothelial cells. Mol Cell Biochem 2014, 386(1-2):15-25.
    • (2014) Mol Cell Biochem , vol.386 , Issue.1-2 , pp. 15-25
    • Prasadam, I.1    Zhou, Y.2    Du, Z.3    Chen, J.4    Crawford, R.5    Xiao, Y.6
  • 45
    • 84873840163 scopus 로고    scopus 로고
    • There are many potential medical therapies for a traumatic osteonecrosis
    • Fessel J. There are many potential medical therapies for a traumatic osteonecrosis. Rheumatology (Oxford) 2013, 52(2):235-241.
    • (2013) Rheumatology (Oxford) , vol.52 , Issue.2 , pp. 235-241
    • Fessel, J.1
  • 46
    • 84877707535 scopus 로고    scopus 로고
    • Zoledronic acid acutely increases sclerostin serum levels in women with postmenopausal osteoporosis
    • Catalano A., Morabito N., Basile G., Brancatelli S., Cucinotta D., Lasco A. Zoledronic acid acutely increases sclerostin serum levels in women with postmenopausal osteoporosis. J Clin Endocrinol Metab 2013, 98(5):1911-1915.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.5 , pp. 1911-1915
    • Catalano, A.1    Morabito, N.2    Basile, G.3    Brancatelli, S.4    Cucinotta, D.5    Lasco, A.6
  • 48
    • 62849083876 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 regulates VEGF production through a vitamin D response element in the VEGF promoter
    • Cardus A., Panizo S., Encinas M., Dolcet X., Gallego C., Aldea M., et al. 1,25-Dihydroxyvitamin D3 regulates VEGF production through a vitamin D response element in the VEGF promoter. Atherosclerosis 2009, 204(1):85-89.
    • (2009) Atherosclerosis , vol.204 , Issue.1 , pp. 85-89
    • Cardus, A.1    Panizo, S.2    Encinas, M.3    Dolcet, X.4    Gallego, C.5    Aldea, M.6
  • 49
    • 77953530668 scopus 로고    scopus 로고
    • Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats
    • Hokugo A., Christensen R., Chung E.M., Sung E.C., Felsenfeld A.L., Sayre J.W., et al. Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats. J Bone Miner Res 2010, 25(6):1337-1349.
    • (2010) J Bone Miner Res , vol.25 , Issue.6 , pp. 1337-1349
    • Hokugo, A.1    Christensen, R.2    Chung, E.M.3    Sung, E.C.4    Felsenfeld, A.L.5    Sayre, J.W.6
  • 50
    • 84865230760 scopus 로고    scopus 로고
    • Osteomalacia: the missing link in the pathogenesis of bisphosphonate-related osteonecrosis of the jaws?
    • Bedogni A., Saia G., Bettini G., Tronchet A., Totola A., Bedogni G., et al. Osteomalacia: the missing link in the pathogenesis of bisphosphonate-related osteonecrosis of the jaws?. Oncologist 2012, 17(8):1114-1119.
    • (2012) Oncologist , vol.17 , Issue.8 , pp. 1114-1119
    • Bedogni, A.1    Saia, G.2    Bettini, G.3    Tronchet, A.4    Totola, A.5    Bedogni, G.6
  • 51
    • 77952307540 scopus 로고    scopus 로고
    • Atypical femoral fractures and bisphosphonate use
    • Girgis C.M., Sher D., Seibel M.J. Atypical femoral fractures and bisphosphonate use. N Engl J Med 2010, 362(19):1848-1849.
    • (2010) N Engl J Med , vol.362 , Issue.19 , pp. 1848-1849
    • Girgis, C.M.1    Sher, D.2    Seibel, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.