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Volumn 9, Issue 12, 2014, Pages

Pre-treatment whole blood gene expression is associated with 14-week response assessed by dynamic contrast enhanced magnetic resonance imaging in infliximab-treated rheumatoid arthritis patients

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; DISEASE MODIFYING ANTIRHEUMATIC DRUG; GADOLINIUM; INFLIXIMAB; METHOTREXATE; PLACEBO; ANTIRHEUMATIC AGENT; MONOCLONAL ANTIBODY;

EID: 84917734196     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113937     Document Type: Article
Times cited : (23)

References (44)
  • 1
    • 33751416149 scopus 로고    scopus 로고
    • Predictors of response to anti-TNF-alpha therapy among patients with rheumatoid arthritis: Results from the British society for rheumatology biologics register
    • Hyrich KL, Watson KD, Silman AJ, Symmons DPM (2006) Predictors of response to anti-TNF-alpha therapy among patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register. Rheumatology (Oxford) 45: 1558-1565.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1558-1565
    • Hyrich, K.L.1    Watson, K.D.2    Silman, A.J.3    Symmons, D.P.M.4
  • 2
    • 70449088927 scopus 로고    scopus 로고
    • Convergent random forest predictor: Methodology for predicting drug response from genome-scale data applied to anti-TNF response
    • Bienkowska JR, Dalgin GS, Batliwalla F, Allaire N, Roubenoff R, et al. (2009) Convergent Random Forest predictor: methodology for predicting drug response from genome-scale data applied to anti-TNF response. Genomics 94: 423-432.
    • (2009) Genomics , vol.94 , pp. 423-432
    • Bienkowska, J.R.1    Dalgin, G.S.2    Batliwalla, F.3    Allaire, N.4    Roubenoff, R.5
  • 3
    • 70449571942 scopus 로고    scopus 로고
    • An eight-gene blood expression profile predicts the response to infliximab in rheumatoid arthritis
    • Julià A, Erra A, Palacio C, Tomas C, Sans X, et al. (2009) An eight-gene blood expression profile predicts the response to infliximab in rheumatoid arthritis. PLoS One 4.
    • (2009) PLoS One , pp. 4
    • Julià, A.1    Erra, A.2    Palacio, C.3    Tomas, C.4    Sans, X.5
  • 4
    • 44449110026 scopus 로고    scopus 로고
    • Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept
    • Koczan D, Drynda S, Hecker M, Drynda A, Guthke R, et al. (2008) Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept. Arthritis Res Ther 10.
    • (2008) Arthritis Res Ther , pp. 10
    • Koczan, D.1    Drynda, S.2    Hecker, M.3    Drynda, A.4    Guthke, R.5
  • 6
    • 44849130695 scopus 로고    scopus 로고
    • Messenger ribonucleic acid expression profile in peripheral blood cells from RA patients following treatment with an anti-TNF-alpha monoclonal antibody, infliximab
    • Sekiguchi N, Kawauchi S, Furuya T, Inaba N, Matsuda K, et al. (2008) Messenger ribonucleic acid expression profile in peripheral blood cells from RA patients following treatment with an anti-TNF-alpha monoclonal antibody, infliximab. Rheumatology (Oxford) 47: 780-788.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 780-788
    • Sekiguchi, N.1    Kawauchi, S.2    Furuya, T.3    Inaba, N.4    Matsuda, K.5
  • 7
    • 77149137696 scopus 로고    scopus 로고
    • CD11c as a transcriptional biomarker to predict response to anti-TNF monotherapy with adalimumab in patients with rheumatoid arthritis
    • Stuhlmuller B, Haupl T, Hernandez MM, Grutzkau A, Kuban RJ, et al. (2010) CD11c as a transcriptional biomarker to predict response to anti-TNF monotherapy with adalimumab in patients with rheumatoid arthritis. Clin Pharmacol Ther 87: 311-321.
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 311-321
    • Stuhlmuller, B.1    Haupl, T.2    Hernandez, M.M.3    Grutzkau, A.4    Kuban, R.J.5
  • 8
    • 67949101911 scopus 로고    scopus 로고
    • Prediction of efficacy of anti-TNF biologic agent, infliximab, for rheumatoid arthritis patients using a comprehensive transcriptome analysis of white blood cells
    • Tanino M, Matoba R, Nakamura S, Kameda H, Amano K, et al. (2009) Prediction of efficacy of anti-TNF biologic agent, infliximab, for rheumatoid arthritis patients using a comprehensive transcriptome analysis of white blood cells. Biochem Biophys Res Commun 387: 261-265.
    • (2009) Biochem Biophys Res Commun , vol.387 , pp. 261-265
    • Tanino, M.1    Matoba, R.2    Nakamura, S.3    Kameda, H.4    Amano, K.5
  • 9
    • 77649289297 scopus 로고    scopus 로고
    • Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment
    • van Baarsen LG, Wijbrandts CA, Rustenburg F, Cantaert T, van der Pouw Kraan TC, et al. (2010) Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment. Arthritis Res Ther 12.
    • (2010) Arthritis Res Ther , pp. 12
    • Van Baarsen, L.G.1    Wijbrandts, C.A.2    Rustenburg, F.3    Cantaert, T.4    Van Der Pouw Kraan, T.C.5
  • 10
    • 84858650504 scopus 로고    scopus 로고
    • Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis
    • Toonen EJM, Gilissen C, Franke B, Kievit W, Eijsbouts AM, et al. (2012) Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis. PLoS One 7.
    • (2012) PLoS One , pp. 7
    • Toonen, E.J.M.1    Gilissen, C.2    Franke, B.3    Kievit, W.4    Eijsbouts, A.M.5
  • 11
    • 2442610650 scopus 로고    scopus 로고
    • Patient-reported outcomes better discriminate active treatment from placebo in randomized controlled trials in rheumatoid arthritis
    • Strand V, Cohen S, Crawford B, Smolen JS, Scott DL (2004) Patient-reported outcomes better discriminate active treatment from placebo in randomized controlled trials in rheumatoid arthritis. Rheumatology (Oxford) 43: 640-647.
    • (2004) Rheumatology (Oxford) , vol.43 , pp. 640-647
    • Strand, V.1    Cohen, S.2    Crawford, B.3    Smolen, J.S.4    Scott, D.L.5
  • 12
    • 0031790352 scopus 로고    scopus 로고
    • Quantification of synovistis by MRI: Correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic and macroscopic signs of synovial inflammation
    • Ostergaard M, Stoltenberg M, Lovgreen-Nielsen P, Volck B, Sonne-Holm S, et al. (1998) Quantification of synovistis by MRI: correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic and macroscopic signs of synovial inflammation. Magn Reson Imaging 16: 743-754.
    • (1998) Magn Reson Imaging , vol.16 , pp. 743-754
    • Ostergaard, M.1    Stoltenberg, M.2    Lovgreen-Nielsen, P.3    Volck, B.4    Sonne-Holm, S.5
  • 13
    • 24144472335 scopus 로고    scopus 로고
    • Quantifying dynamic contrast-enhanced MRI of the knee in children with juvenile rheumatoid arthritis using an arterial input function (AIF) extracted from popliteal artery enhancement, and the effect of the choice of the AIF on the kinetic parameters
    • Workie DW, Dardzinski BJ (2005) Quantifying dynamic contrast-enhanced MRI of the knee in children with juvenile rheumatoid arthritis using an arterial input function (AIF) extracted from popliteal artery enhancement, and the effect of the choice of the AIF on the kinetic parameters. Magn Reson Med 54: 560-568.
    • (2005) Magn Reson Med , vol.54 , pp. 560-568
    • Workie, D.W.1    Dardzinski, B.J.2
  • 14
    • 37349083481 scopus 로고    scopus 로고
    • MRI of rheumatoid arthritis image quantitation for the assessment of disease activity, progression and response to therapy
    • Hodgson RJ, O'Connor P, Moots R (2008) MRI of rheumatoid arthritis image quantitation for the assessment of disease activity, progression and response to therapy. Rheumatology (Oxford) 47: 13-21.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 13-21
    • Hodgson, R.J.1    O'Connor, P.2    Moots, R.3
  • 15
    • 0028815803 scopus 로고
    • Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis
    • Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, et al. (1995) Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 38: 44-48.
    • (1995) Arthritis Rheum , vol.38 , pp. 44-48
    • Prevoo, M.L.1    Van 'T Hof, M.A.2    Kuper, H.H.3    Van Leeuwen, M.A.4    Van De Putte, L.B.5
  • 16
    • 0038047700 scopus 로고    scopus 로고
    • OMERACT rheumatoid arthritis magnetic resonance imaging studies. Summary of OMERACT 6 MR imaging module
    • McQueen F, Lassere M, Edmonds J, Conaghan P, Peterfy C, et al. (2003) OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Summary of OMERACT 6 MR Imaging Module. J Rheumatol 30: 1387-1392.
    • (2003) J Rheumatol , vol.30 , pp. 1387-1392
    • McQueen, F.1    Lassere, M.2    Edmonds, J.3    Conaghan, P.4    Peterfy, C.5
  • 17
    • 0003244085 scopus 로고    scopus 로고
    • Longitudinal data analysis of continuous and discrete responses for pre-post designs
    • Liang KY ZS (2000) Longitudinal data analysis of continuous and discrete responses for pre-post designs. Indian Journal of Statistics 62: 134-148.
    • (2000) Indian Journal Of Statistics , vol.62 , pp. 134-148
    • Liang, K.Y.Z.S.1
  • 18
    • 33644790320 scopus 로고    scopus 로고
    • The disease activity score and the EULAR response criteria
    • Fransen J, van Riel PLCM (2005) The Disease Activity Score and the EULAR response criteria. Clin Exp Rheumatol 23: 93-99.
    • (2005) Clin Exp Rheumatol , vol.23 , pp. 93-99
    • Fransen, J.1    Van Riel, P.L.C.M.2
  • 19
    • 84894288992 scopus 로고    scopus 로고
    • Genetics of rheumatoid arthritis contributes to biology and drug discovery
    • Okada Y, Wu D, Trynka G, Raj T, Terao C, et al. (2014) Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature 506: 376-381.
    • (2014) Nature , vol.506 , pp. 376-381
    • Okada, Y.1    Wu, D.2    Trynka, G.3    Raj, T.4    Terao, C.5
  • 20
    • 79955149975 scopus 로고    scopus 로고
    • The relevance of citrullinated vimentin in the production of antibodies against citrullinated proteins and the pathogenesis of rheumatoid arthritis
    • Van Steendam K, Tilleman K, Deforce D (2011) The relevance of citrullinated vimentin in the production of antibodies against citrullinated proteins and the pathogenesis of rheumatoid arthritis. Rheumatology (Oxford) 50: 830-837.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 830-837
    • Van Steendam, K.1    Tilleman, K.2    Deforce, D.3
  • 21
    • 35948988045 scopus 로고    scopus 로고
    • Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate
    • Parker A, Izmailova ES, Narang J, Badola S, Le T, et al. (2007) Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate. J Rheumatol 34: 1817-1822.
    • (2007) J Rheumatol , vol.34 , pp. 1817-1822
    • Parker, A.1    Izmailova, E.S.2    Narang, J.3    Badola, S.4    Le, T.5
  • 23
    • 67651230876 scopus 로고    scopus 로고
    • Apolipoprotein A-I and platelet factor 4 are biomarkers for infliximab response in rheumatoid arthritis
    • Trocme C, Marotte H, Baillet A, Pallot-Prades B, Garin J, et al. (2009) Apolipoprotein A-I and platelet factor 4 are biomarkers for infliximab response in rheumatoid arthritis. Ann Rheum Dis 68: 1328-1333.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1328-1333
    • Trocme, C.1    Marotte, H.2    Baillet, A.3    Pallot-Prades, B.4    Garin, J.5
  • 24
    • 46749152178 scopus 로고    scopus 로고
    • A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus
    • Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, et al. (2008) A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 29: 150-164.
    • (2008) Immunity , vol.29 , pp. 150-164
    • Chaussabel, D.1    Quinn, C.2    Shen, J.3    Patel, P.4    Glaser, C.5
  • 25
    • 80455131338 scopus 로고    scopus 로고
    • Genetic and genomic predictors of anti-TNF response
    • Prajapati R, Plant D, Barton A (2011) Genetic and genomic predictors of anti-TNF response. Pharmacogenomics 12: 1571-1585.
    • (2011) Pharmacogenomics , vol.12 , pp. 1571-1585
    • Prajapati, R.1    Plant, D.2    Barton, A.3
  • 26
    • 34447320793 scopus 로고    scopus 로고
    • Regression to the mean using the disease activity score in eligibility and response criteria for prescribing TNF-alpha inhibitors in adults with rheumatoid arthritis
    • Greenwood MC, Rathi J, Hakim AJ, Scott DL, Doyle DV (2007) Regression to the mean using the disease activity score in eligibility and response criteria for prescribing TNF-alpha inhibitors in adults with rheumatoid arthritis. Rheumatology (Oxford) 46: 1165-1167.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 1165-1167
    • Greenwood, M.C.1    Rathi, J.2    Hakim, A.J.3    Scott, D.L.4    Doyle, D.V.5
  • 29
    • 84885152521 scopus 로고    scopus 로고
    • Review: The utility of magnetic resonance imaging for assessing structural damage in randomized controlled trials in rheumatoid arthritis
    • American College of Rheumatology Rheumatoid Arthritis Clinical Trials Task Force Imaging G,Outcome Measures in Rheumatology Magnetic Resonance Imaging Inflammatory Arthritis Working G
    • American College of Rheumatology Rheumatoid Arthritis Clinical Trials Task Force Imaging G, Outcome Measures in Rheumatology Magnetic Resonance Imaging Inflammatory Arthritis Working G (2013) Review: the utility of magnetic resonance imaging for assessing structural damage in randomized controlled trials in rheumatoid arthritis. Arthritis Rheum 65: 2513-2523.
    • (2013) Arthritis Rheum , vol.65 , pp. 2513-2523
  • 30
    • 84877930285 scopus 로고    scopus 로고
    • Reliability and responsiveness of dynamic contrast-enhanced magnetic resonance imaging in rheumatoid arthritis
    • Axelsen MB, Poggenborg RP, Stoltenberg M, Kubassova O, Boesen M, et al. (2013) Reliability and responsiveness of dynamic contrast-enhanced magnetic resonance imaging in rheumatoid arthritis. Scand J Rheumatol 42: 115-122.
    • (2013) Scand J Rheumatol , vol.42 , pp. 115-122
    • Axelsen, M.B.1    Poggenborg, R.P.2    Stoltenberg, M.3    Kubassova, O.4    Boesen, M.5
  • 31
    • 38749145968 scopus 로고    scopus 로고
    • Dynamic contrast enhanced MRI of bone marrow oedema in rheumatoid arthritis
    • Hodgson R, Grainger A, O'Connor P, Barnes T, Connolly S, et al. (2008) Dynamic contrast enhanced MRI of bone marrow oedema in rheumatoid arthritis. Ann Rheum Dis 67: 270-272.
    • (2008) Ann Rheum Dis , vol.67 , pp. 270-272
    • Hodgson, R.1    Grainger, A.2    O'Connor, P.3    Barnes, T.4    Connolly, S.5
  • 32
    • 84879695453 scopus 로고    scopus 로고
    • Comparison of OMERACT-RAMRIS scores and computer-aided dynamic magnetic resonance imaging findings of hand and wrist as a measure of activity in rheumatoid arthritis
    • Orguc S, Tikiz C, Aslanalp Z, Erbay PD (2013) Comparison of OMERACT-RAMRIS scores and computer-aided dynamic magnetic resonance imaging findings of hand and wrist as a measure of activity in rheumatoid arthritis. Rheumatol Int 33: 1837-1844.
    • (2013) Rheumatol Int , vol.33 , pp. 1837-1844
    • Orguc, S.1    Tikiz, C.2    Aslanalp, Z.3    Erbay, P.D.4
  • 33
    • 84865627767 scopus 로고    scopus 로고
    • Differential effects of infliximab on absolute circulating blood leucocyte counts of innate immune cells in early and late rheumatoid arthritis patients
    • Coulthard LR, Geiler J, Mathews RJ, Church LD, Dickie LJ, et al. (2012) Differential effects of infliximab on absolute circulating blood leucocyte counts of innate immune cells in early and late rheumatoid arthritis patients. Clin Exp Immunol 170: 36-46.
    • (2012) Clin Exp Immunol , vol.170 , pp. 36-46
    • Coulthard, L.R.1    Geiler, J.2    Mathews, R.J.3    Church, L.D.4    Dickie, L.J.5
  • 34
    • 84866331514 scopus 로고    scopus 로고
    • Myeloid skewing in murine autoimmune arthritis occurs in hematopoietic stem and primitive progenitor cells
    • Oduro KA, Liu F, Tan Q, Kim C-K, Lubman O, et al. (2012) Myeloid skewing in murine autoimmune arthritis occurs in hematopoietic stem and primitive progenitor cells. Blood 120: 2203-2213.
    • (2012) Blood , vol.120 , pp. 2203-2213
    • Oduro, K.A.1    Liu, F.2    Tan, Q.3    Kim, C.-K.4    Lubman, O.5
  • 35
    • 0025241216 scopus 로고
    • Cytokine regulation of colony-stimulating factor production in cultured human synovial fibroblasts: I. Induction of GM-CSF and G-CSF production by interleukin-1 and tumor necrosis factor
    • Leizer T, Cebon J, Layton JE, Hamilton JA (1990) Cytokine regulation of colony-stimulating factor production in cultured human synovial fibroblasts: I. Induction of GM-CSF and G-CSF production by interleukin-1 and tumor necrosis factor. Blood 76: 1989-1996.
    • (1990) Blood , vol.76 , pp. 1989-1996
    • Leizer, T.1    Cebon, J.2    Layton, J.E.3    Hamilton, J.A.4
  • 36
    • 0023685534 scopus 로고
    • Tumor necrosis factor-alpha and tumor necrosis factor-beta (lymphotoxin) stimulate the production of granulocyte-macrophage colonystimulating factor, macrophage colony-stimulating factor, and IL-1 in vivo
    • Kaushansky K, Broudy VC, Harlan JM, Adamson JW (1988) Tumor necrosis factor-alpha and tumor necrosis factor-beta (lymphotoxin) stimulate the production of granulocyte-macrophage colonystimulating factor, macrophage colony-stimulating factor, and IL-1 in vivo. J Immunol 141: 3410-3415.
    • (1988) J Immunol , vol.141 , pp. 3410-3415
    • Kaushansky, K.1    Broudy, V.C.2    Harlan, J.M.3    Adamson, J.W.4
  • 37
    • 84866113069 scopus 로고    scopus 로고
    • Platelets: Active players in the pathogenesis of arthritis and SLE
    • Boilard E, Blanco P, Nigrovic PA (2012) Platelets: active players in the pathogenesis of arthritis and SLE. Nat Rev Rheumatol 8: 534-542.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 534-542
    • Boilard, E.1    Blanco, P.2    Nigrovic, P.A.3
  • 38
    • 24744432090 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha as trigger of platelet activation in patients with heart failure
    • Pignatelli P, De Biase L, Lenti L, Tocci G, Brunelli A, et al. (2005) Tumor necrosis factor-alpha as trigger of platelet activation in patients with heart failure. Blood 106: 1992-1994.
    • (2005) Blood , vol.106 , pp. 1992-1994
    • Pignatelli, P.1    De Biase, L.2    Lenti, L.3    Tocci, G.4    Brunelli, A.5
  • 39
    • 0029096412 scopus 로고
    • Effects of interleukin-1 and tumor necrosis factor on megakaryocytopoiesis: Mechanism of reactive thrombocytosis
    • Dan K, Gomi S, Inokuchi K, Ogata K, Yamada T, et al. (1995) Effects of interleukin-1 and tumor necrosis factor on megakaryocytopoiesis: mechanism of reactive thrombocytosis. Acta Haematol 93: 67-72.
    • (1995) Acta Haematol , vol.93 , pp. 67-72
    • Dan, K.1    Gomi, S.2    Inokuchi, K.3    Ogata, K.4    Yamada, T.5
  • 40
    • 63849306606 scopus 로고    scopus 로고
    • Phase 2 trial of recombinant tumor necrosis factor-alpha in combination with dactinomycin in children with recurrent Wilms tumor
    • Meany HJ, Seibel NL, Sun J, Finklestein JZ, Sato J, et al. (2008) Phase 2 trial of recombinant tumor necrosis factor-alpha in combination with dactinomycin in children with recurrent Wilms tumor. J Immunother 31: 679-683.
    • (2008) J Immunother , vol.31 , pp. 679-683
    • Meany, H.J.1    Seibel, N.L.2    Sun, J.3    Finklestein, J.Z.4    Sato, J.5
  • 41
    • 0035997255 scopus 로고    scopus 로고
    • Activation of platelet caspases by TNF and its consequences for kinetics
    • Piguet PF, Vesin C, Da Kan C (2002) Activation of platelet caspases by TNF and its consequences for kinetics. Cytokine 18: 222-230.
    • (2002) Cytokine , vol.18 , pp. 222-230
    • Piguet, P.F.1    Vesin, C.2    Da Kan, C.3
  • 43
    • 0347285361 scopus 로고    scopus 로고
    • Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression
    • Ueda Y, Yang K, Foster SJ, Kondo M, Kelsoe G (2004) Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. J Exp Med 199: 47-58.
    • (2004) J Exp Med , vol.199 , pp. 47-58
    • Ueda, Y.1    Yang, K.2    Foster, S.J.3    Kondo, M.4    Kelsoe, G.5
  • 44
    • 84866773063 scopus 로고    scopus 로고
    • Rituximab is more effective than second anti-TNF therapy in rheumatoid arthritis patients and previous TNFa blocker failure
    • Kekow J, Mueller-Ladner U, Schulze-Koops H (2012) Rituximab is more effective than second anti-TNF therapy in rheumatoid arthritis patients and previous TNFa blocker failure. Biologics 6: 191-199.
    • (2012) Biologics , vol.6 , pp. 191-199
    • Kekow, J.1    Mueller-Ladner, U.2    Schulze-Koops, H.3


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