A 12-year survey of methicillin-resistant staphylococcus aureus infections in greece: ST80-IV epidemic?

Clinical Microbiology and Infection

Volumn 20, Issue 11, 2014, Pages O796-O803

  Drougka, E ^a,b   Foka, A ^a,b   Liakopoulos, A ^c   Doudoulakakis, A ^d   Jelastopulu, E ^a   Chini, V ^a,h   Spiliopoulou, A ^e   Levidiotou, S ^f   Panagea, T ^g,i   Vogiatzi, A ^g   Lebessi, E ^d   Petinaki, E ^c   Spiliopoulou, I ^a,b  

^a UNIVERSITY OF PATRAS   (Greece)

^b National Reference Laboratory for Staphylococci   (Greece)

^c UNIVERSITY OF THESSALY   (Greece)

^d P AND A KYRIAKOU CHILDREN S HOSPITAL   (Greece)

^e Karamandaneion Children's Hospital   (Greece)

^f UNIVERSITY OF IOANNINA   (Greece)

^g Children's Hospital of Pentelis   (Greece)

^h Shafallah Medical Genetics Center   (Qatar)

ⁱ AMALIA FLEMING GENERAL HOSPITAL   (Greece)

Author keywords

Clones; Epidemiology; Greece; Methicillin resistant staphylococcus aureus; ST80 IV; Toxins

Indexed keywords

AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; DAPTOMYCIN; LINCOSAMIDE; LINEZOLID; QUINOLONE DERIVATIVE; RNA 16S; TOXIC SHOCK SYNDROME TOXIN 1; VANCOMYCIN; VIRULENCE FACTOR; BACTERIAL TOXIN;

ADULT; AGAR DILUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; DISK DIFFUSION; ELECTROPHORESIS; EMERGENCY WARD; EPIDEMIC; FEMALE; GENE CLUSTER; GREECE; HEALTH CARE SURVEY; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; LATEX AGGLUTINATION TEST; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MOLECULAR TYPING; MULTILOCUS SEQUENCE TYPING; OPERON; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SEASONAL VARIATION; SOFT TISSUE INFECTION; UNIVERSITY HOSPITAL; CHILD; CLASSIFICATION; COMMUNITY-ACQUIRED INFECTIONS; CROSS INFECTION; DRUG EFFECTS; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOLECULAR EPIDEMIOLOGY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; STAPHYLOCOCCAL INFECTIONS;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

ADULT; ANTI-BACTERIAL AGENTS; BACTERIAL TOXINS; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; CROSS INFECTION; EPIDEMICS; FEMALE; GENOTYPE; GREECE; HUMANS; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR EPIDEMIOLOGY; MOLECULAR TYPING; POLYMERASE CHAIN REACTION; STAPHYLOCOCCAL INFECTIONS; VIRULENCE FACTORS;

EID: 84917674559     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/1469-0691.12624     Document Type: Article

References (31)

1. Lowy FD. Staphylococcus aureus infections. N Engl J Med 1998; 339: 520-532.
2. Stefani S, Chung DR, Lindsay JA et al. Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods. Int J Antimicrob Agents 2012; 39: 273-282.
3. Grundmann H, Aires-de-Sousa M, Boyce J, Tiemersma E. Emergence and resurgence of meticillin-resistant Staphylococcus aureus as a public-health threat. Lancet 2006; 368: 874-885.
4. Deurenberg RH, Stobberingh EE. The evolution of Staphylococcus aureus. Infect Genet Evol 2008; 8: 747-763.
5. Gould IM. Control of methicillin-resistant Staphylococcus aureus in the UK. Eur J Clin Microbiol Infect Dis 2005; 24: 789-793.
6. Lindsay JA. Genomic variation and evolution of Staphylococcus aureus. Int J Med Microbiol 2010; 300: 98-103.
7. Malachowa N, DeLeo FR. Mobile genetic elements of Staphylococcus aureus. Cell Mol Life Sci 2010; 67: 3057-3071.
8. Campanile F, Bongiorno D, Borbone S, Stefani S. Hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) in Italy. Ann Clin Microbiol Antimicrob 2009; 8: 22.
9. Lina G, Piemont Y, Godail-Gamot F et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999; 29: 1128-1132.
10. Yamasaki O, Kaneko J, Morizane S et al. The association between Staphylococcus aureus strains carrying Panton-Valentine leukocidin genes and the development of deep-seated follicular infection. Clin Infect Dis 2005; 40: 381-385.
11. Aires de Sousa M, Bartzavali C, Spiliopoulou I, Sanches IS, Crisostomo MI, de Lencastre H. Two international methicillin-resistant Staphylococcus aureus clones endemic in a university hospital in Patras, Greece. J Clin Microbiol 2003; 41: 2027-2032.
12. Okuma K, Iwakawa K, Turnidge JD et al. Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community. J Clin Microbiol 2002; 40: 4289-4294.
13. Chini V, Petinaki E, Foka A, Paratiras S, Dimitracopoulos G, Spiliopoulou I. Spread of Staphylococcus aureus clinical isolates carrying Panton-Valentine leukocidin genes during a 3-year period in Greece. Clin Microbiol Infect 2006; 12: 29-34.
14. Otter JA, French GL. Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Europe. Lancet Infect Dis 2010; 10: 227-239.
15. Witte W. Community-acquired methicillin-resistant Staphylococcus aureus: what do we need to know? Clin Microbiol Infect 2009; 15(suppl 7): 17-25.
16. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008; 36: 309-332.
17. Zhang K, Sparling J, Chow BL et al. New quadriplex PCR assay for detection of methicillin and mupirocin resistance and simultaneous discrimination of Staphylococcus aureus from coagulase-negative staphylococci. J Clin Microbiol 2004; 42: 4947-4955.
18. Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 12th edn. Approved standard M7-A7. Wayne, PA: CLSI, 2011.
19. The European Committee on Antimicrobial Susceptibility Testing (EUCAST). Breakpoint tables for interpretations of MICs and zone diameters. Version 2.0, February 2012. Available at: http://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Disk_test_documents/EUCAST_breakpoints_v2.0.pdf (last accessed 1 February 2012).
20. Jarraud S, Mougel C, Thioulouse J et al. Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease. Infect Immun 2002; 70: 631-641.
21. Tenover FC, Arbeit RD, Goering RV et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33: 2233-2239.
22. Oliveira DC, de Lencastre H. Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2002; 46: 2155-2161.
23. Sakoulas G, Moellering RC Jr. Increasing antibiotic resistance among methicillin-resistant Staphylococcus aureus strains. Clin Infect Dis 2008; 46(suppl 5): S360-S367.
24. Sdougkos G, Chini V, Papanastasiou DA et al. Community-associated Staphylococcus aureus infections and nasal carriage among children: molecular microbial data and clinical characteristics. Clin Microbiol Infect 2008; 14: 995-1001.
25. Mermel LA, Cartony JM, Covington P, Maxey G, Morse D. Methicillin-resistant Staphylococcus aureus colonization at different body sites: a prospective, quantitative analysis. J Clin Microbiol 2011; 49: 1119-1121.
26. Rossney AS, Shore AC, Morgan PM, Fitzgibbon MM, O'Connell B, Coleman DC. The emergence and importation of diverse genotypes of methicillin-resistant Staphylococcus aureus (MRSA) harboring the Panton-Valentine leukocidin gene (PVL) reveal that PVL is a poor marker for community-acquired MRSA strains in Ireland. J Clin Microbiol 2007; 45: 2554-2563.
27. DeLeo FR, Otto M, Kreiswirth BN, Chambers HF. Community-associated meticillin-resistant Staphylococcus aureus. Lancet 2010; 375: 1557-1568.
28. Vourli S, Vagiakou H, Ganteris G et al. High rates of community-acquired, Panton-Valentine leukocidin (PVL)-positive methicillin-resistant S. aureus (MRSA) infections in adult outpatients in Greece. Euro Surveill. 2009; 14: 19089.
29. Dailiana ZH, Rigopoulos N, Varitimidis SE, Poultsides L, Petinaki E, Malizos KN. Clinical and epidemiological features of upper-extremity infections caused by Staphylococcus aureus carrying the PVL gene: a four-year study in Greece. Med Sci Monit 2008; 14: CR511-CR514.
30. Vandenesch F, Naimi T, Enright MC et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis 2003; 9: 978-984.
31. Alp E, Klaassen CH, Doganay M et al. MRSA genotypes in Turkey: persistence over 10 years of a single clone of ST239. J Infect 2009; 58: 433-438.