Improved surveillance for hepatocellular carcinoma with a primary care-oriented clinical reminder

Clinical Gastroenterology and Hepatology

Volumn 13, Issue 1, 2015, Pages 172-179

  Beste, Lauren A ^a,b   Ioannou, George N ^a,c   Yang, Yin ^a   Chang, Michael F ^d,e   Ross, David ^f,g   Dominitz, Jason A ^a,c  

^a VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d PORTLAND VA MEDICAL CENTER   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f DEPARTMENT OF VETERANS AFFAIRS   (United States)

^g GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Cirrhosis; Liver cancer; Screening; Veterans

Indexed keywords

ADULT; ARTICLE; CANCER EPIDEMIOLOGY; CANCER SCREENING; CANCER STAGING; CONFIDENCE INTERVAL; CONTROLLED STUDY; ELECTRONIC MEDICAL RECORD; FEMALE; HUMAN; INTEGRATED HEALTH CARE SYSTEM; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OUTCOME ASSESSMENT; PRIMARY MEDICAL CARE; QUASI EXPERIMENTAL STUDY; STATISTICAL ANALYSIS; ULTRASOUND; VETERAN; AGED; CARCINOMA, HEPATOCELLULAR; COMPLICATION; CONTROLLED CLINICAL TRIAL (TOPIC); ECHOGRAPHY; LIVER; PATHOLOGY; PRIMARY HEALTH CARE; PROCEDURES; REMINDER SYSTEM;

AGED; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; NON-RANDOMIZED CONTROLLED TRIALS AS TOPIC; PRIMARY HEALTH CARE; REMINDER SYSTEMS;

EID: 84917674258     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2014.04.033     Document Type: Article

References (32)

1. El-Serag H.B., Rudolph K.L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007, 132:2557-2576.
2. Edwards B.K., Ward E., Kohler B.A., et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 2010, 116:544-573.
3. Stravitz R.T., Heuman D.M., Chand N., et al. Surveillance for hepatocellular carcinoma in patients with cirrhosis improves outcome. Am J Med 2008, 121:119-126.
4. Davila J.A., Weston A., Smalley W., et al. Utilization of screening for hepatocellular carcinoma in the United States. JClin Gastroenterol 2007, 41:777-782.
5. Davila J.A., Henderson L., Kramer J.R., et al. Utilization of surveillance for hepatocellular carcinoma among hepatitis C virus-infected veterans in the United States. Ann Intern Med 2011, 154:85-93.
6. Davila J.A., Morgan R.O., Richardson P.A., et al. Use of surveillance for hepatocellular carcinoma among patients with cirrhosis in the United States. Hepatology 2010, 52:132-141.
7. El-Serag H.B. Hepatocellular carcinoma: recent trends in the United States. Gastroenterology 2004, 127:S27-S34.
8. Singal A.G., Marrero J.A. Recent advances in the treatment of hepatocellular carcinoma. Curr Opin Gastroenterol 2010, 26:189-195.
9. EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. JHepatol 2012, 56:908-943.
10. Omata M., Lesmana L.A., Tateishi R., et al. Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma. Hepatol Int 2010, 4:439-474.
11. Bruix J., Sherman M. Management of hepatocellular carcinoma: an update. Hepatology 2011, 53:1020-1022.
12. U.S. Department of Veterans Affairs, Veterans Health Administration, VA Hepatitis C Resource Center Program & VA National Clinical Public Health Program. Management of hepatocellular carcinoma (HCC) clinician's guide from the hepatitis C resource centers. September 2009.
13. Trevisani F., Santi V., Gramenzi A., et al. Surveillance for early diagnosis of hepatocellular carcinoma: is it effective in intermediate/advanced cirrhosis?. Am J Gastroenterol 2007, 102:2448-2457. quiz 2458.
14. Trevisani F., Cantarini M.C., Labate A.M., et al. Surveillance for hepatocellular carcinoma in elderly Italian patients with cirrhosis: effects on cancer staging and patient survival. Am J Gastroenterol 2004, 99:1470-1476.
15. Singal A.G., Yopp A.C., Gupta S., et al. Failure rates in the hepatocellular carcinoma surveillance process. Cancer Prev Res (Phila) 2012, 5:1124-1130.
16. Singal A.G., Yopp A., Skinner S.C., et al. Utilization of hepatocellular carcinoma surveillance among American patients: a systematic review. JGen Intern Med 2012, 27:861-867.
17. Sanyal A.J. How to close the gap between the numbers of patients who need liver care and the providers available. AASLD eNews 2010, Available at:, Accessed June 12, 2014. http://www.aasld.org/journals/archive/022510/Pages/default.aspx.
18. Shojania K.G., Jennings A., Mayhew A., et al. Effect of point-of-care computer reminders on physician behaviour: a systematic review. CMAJ 2010, 182:E216-E225.
19. Saleem J.J., Patterson E.S., Militello L., et al. Exploring barriers and facilitators to the use of computerized clinical reminders. JAm Med Inform Assoc 2005, 12:438-447.
20. Ishizaki Y., Kawasaki S. The evolution of liver transplantation forhepatocellular carcinoma (past, present, and future). JGastroenterol 2008, 43:18-26.
21. Mazzaferro V., Regalia E., Doci R., et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. NEngl J Med 1996, 334:693-699.
22. Deyo R.A., Cherkin D.C., Ciol M.A. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. JClin Epidemiol 1992, 45:613-619.
23. Kamath P.S., Kim W.R. The model for end-stage liver disease (MELD). Hepatology 2007, 45:797-805.
24. Austin P.C. Comparing paired vs non-paired statistical methods of analyses when making inferences about absolute risk reductions in propensity-score matched samples. Stat Med 2011, 30:1292-1301.
25. Brookhart M.A., Schneeweiss S., Rothman K.J., et al. Variable selection for propensity score models. Am J Epidemiol 2006, 163:1149-1156.
26. Shojania K.G., Jennings A., Mayhew A., et al. The effects of on-screen, point of care computer reminders on processes and outcomes of care. Cochrane Database Syst Rev 2009, 3:CD001096.
27. Trevisani F., De Notariis S., Rapaccini G., et al. Semiannual and annual surveillance of cirrhotic patients for hepatocellular carcinoma: effects on cancer stage and patient survival (Italian experience). Am J Gastroenterol 2002, 97:734-744.
28. Yu E.W., Chie W.C., Chen T.H. Does screening or surveillance for primary hepatocellular carcinoma with ultrasonography improve the prognosis of patients?. Cancer J 2004, 10:317-325.
29. Wong L.L., Limm W.M., Severino R., et al. Improved survival with screening for hepatocellular carcinoma. Liver Transpl 2000, 6:320-325.
30. Leykum L.K., El-Serag H.B., Cornell J., et al. Screening for hepatocellular carcinoma among veterans with hepatitis C on disease stage, treatment received, and survival. Clin Gastroenterol Hepatol 2007, 5:508-512.
31. Aberra F.B., Essenmacher M., Fisher N., et al. Quality improvement measures lead to higher surveillance rates for hepatocellular carcinoma in patients with cirrhosis. Dig Dis Sci 2013, 58:1157-1160.
32. Wai C.T., Greenson J.K., Fontana R.J., et al. Asimple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003, 38:518-526.