Docetaxel epimerization in silicone films: A case of drug excipient incompatibility

Drug Testing and Analysis

Volumn 6, Issue 10, 2014, Pages 1076-1084

  Mohsin, Shaikh ^a   Arellano, Ian Harvey ^a   Choudhury, Namita Roy ^a   Garg, Sanjay ^a  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

Chemical incompatibility; Degradation; Docetaxel; Epimerization; Silicone

Indexed keywords

CONTROLLED DRUG DELIVERY; DEGRADATION; DISEASES; DRUG PRODUCTS; METALLIC FILMS; TARGETED DRUG DELIVERY; TUMORS;

BACCATIN III; CHEMICAL INCOMPATIBILITY; CONTROLLED-DELIVERY; DOCETAXEL; EPIMERIZATION; HEAD-AND-NECK CANCER; IN-VITRO; LOCALISED; RELEASE MEDIA; TUMOUR CELLS;

SILICONES;

DOCETAXEL; EXCIPIENT; SILASTIC; SILICONE; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; SILICONE DERIVATIVE; TAXOID;

ARTICLE; CATALYST; COMPLEX FORMATION; DRUG DEGRADATION; DRUG IMPURITY; DRUG INCOMPATIBILITY; DRUG SOLUBILITY; DRUG STABILITY; EPIMERIZATION; IN VITRO STUDY; MICROENVIRONMENT; PH; PRIORITY JOURNAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG RELEASE; MEDICINAL CHEMISTRY; PROCEDURES;

ANTINEOPLASTIC AGENTS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG INCOMPATIBILITY; DRUG LIBERATION; DRUG STABILITY; EXCIPIENTS; SILICONES; TAXOIDS;

EID: 84916937130     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.1617     Document Type: Article

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