Impact of minocycline on cerebrospinal fluid markers of oxidative stress, neuronal injury, and inflammation in HIV-seropositive individuals with cognitive impairment

Journal of NeuroVirology

Volumn 20, Issue 6, 2014, Pages 620-626

  Sacktor, Ned ^a   Miyahara, Sachiko ^b   Evans, Scott ^b   Schifitto, Giovanni ^c   Cohen, Bruce ^d   Haughey, Norman ^a   Drewes, Julia L ^a   Graham, David ^a   Zink, M Christine ^a   Anderson, Caroline ^e   Nath, Avindra ^e   Pardo, Carlos A ^a   McCarthy, Sean ^f   Hosey, Lara ^f   Clifford, David ^g  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF ROCHESTER   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f AIDS Clinical Trial Group Operations Center   (United States)

^g WASHINGTON UNIVERSITY   (United States)

Author keywords

Biomarker; Cognitive; HIV; Minocycline; Oxidative; Stress

Indexed keywords

BIOLOGICAL MARKER; CARBONYL DERIVATIVE; CERAMIDE; KYNURENINE; LIPID; MINOCYCLINE; NEUROTRANSMITTER; PLACEBO; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CYTOKINE; GLUTAMIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; NEUROFILAMENT PROTEIN; NEUROFILAMENT PROTEIN H; NEUROPROTECTIVE AGENT; NOS2 PROTEIN, HUMAN;

ADULT; ARTICLE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HEAVY CHAIN; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; LUMBAR PUNCTURE; MALE; NEUROFILAMENT; OXIDATIVE STRESS; PROTEIN CEREBROSPINAL FLUID LEVEL; RANDOMIZED CONTROLLED TRIAL; ACQUIRED IMMUNODEFICIENCY SYNDROME; AIDS DEMENTIA COMPLEX; CLINICAL TRIAL; DRUG EFFECTS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN IMMUNODEFICIENCY VIRUS 1; MIDDLE AGED; NERVE CELL; ORAL DRUG ADMINISTRATION; PATHOLOGY; PHASE 2 CLINICAL TRIAL; PHYSIOLOGY; VIROLOGY;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADMINISTRATION, ORAL; ADULT; AIDS DEMENTIA COMPLEX; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CERAMIDES; CYTOKINES; DOUBLE-BLIND METHOD; FEMALE; GLUTAMIC ACID; HIV-1; HUMANS; KYNURENINE; MALE; MIDDLE AGED; MINOCYCLINE; NEUROFILAMENT PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS;

EID: 84916930729     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-014-0292-0     Document Type: Article

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