Carbonic Anhydrase Generates CO2 and H+ That Drive Spider Silk Formation Via Opposite Effects on the Terminal Domains

PLoS Biology

Volumn 12, Issue 8, 2014, Pages

  Andersson, Marlene ^a   Chen, Gefei ^b   Otikovs, Martins ^c   Landreh, Michael ^d   Nordling, Kerstin ^d   Kronqvist, Nina ^d   Westermark, Per ^e   Jörnvall, Hans ^d   Knight, Stefan ^e   Ridderstråle, Yvonne ^a   Holm, Lena ^a   Meng, Qing ^b   Jaudzems, Kristaps ^c   Chesler, Mitchell ^f   Johansson, Jan ^a,d,g   Rising, Anna ^a,d  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b DONGHUA UNIVERSITY   (China)

^c LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UPPSALA UNIVERSITY   (Sweden)

^f NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g TALLINN UNIVERSITY   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; CARBONATE DEHYDRATASE; DIMER; HYDROGEN; MEMBRANE PROTEIN; SILK; SPIDROIN; UNCLASSIFIED DRUG; UREA; BICARBONATE; PROTON;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBON DIOXIDE TENSION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DENATURATION; ENZYME ACTIVITY; ENZYME ASSAY; FIBER; HUMAN; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH MEASUREMENT; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN UNFOLDING; SILK FIBER; SPIDER; STRUCTURE ANALYSIS; TEMPERATURE SENSITIVITY; THERMOSTABILITY; AMINO ACID SEQUENCE; ANIMAL; ANIMAL STRUCTURES; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; ELECTROSPRAY MASS SPECTROMETRY; ENZYMOLOGY; FEMALE; METABOLISM; MOLECULAR GENETICS; PH; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; TEMPERATURE; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; ANIMAL STRUCTURES; ANIMALS; BICARBONATES; CARBON DIOXIDE; CARBONIC ANHYDRASES; CIRCULAR DICHROISM; FEMALE; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTONS; SILK; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPIDERS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 84916630544     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001921     Document Type: Article

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