Inhibition of poly (ADP-ribose) polymerase and inducible nitric oxide synthase protects against ischemic myocardial damage by reduction of apoptosis

Molecular Medicine Reports

Volumn 11, Issue 3, 2015, Pages 1768-1776

  Wang, Juan ^a   Hao, Lin ^a   Wang, Yan ^a   Qin, Weidong ^b   Wang, Xin ^a   Zhao, Tong ^a   Liu, Yusheng ^a   Sheng, Lin ^a   Du, Yimeng ^a   Zhang, Mengyuan ^a   Lu, Qinghua ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Inducible nitric oxide synthase; Myocardial infarction; Peroxynitrite; Poly (ADP ribose) polymerase 1

Indexed keywords

3 NITROTYROSINE; 3,4 DIHYDRO 5[4 (1 PIPERIDINYL)BUTOXY] 1(2H)ISOQUINOLINONE; CASPASE 3; DIMETHYL SULFOXIDE; DNA NUCLEOTIDYLEXOTRANSFERASE; INDUCIBLE NITRIC OXIDE SYNTHASE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OXYGEN; PENTOBARBITAL; QUINOLINE DERIVATIVE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; 3,4-DIHYDRO-5-(4-(1-PIPERIDINYL)BUTOXY)-1(2H)-ISOQUINOLINONE; AMIDINE; BENZYLAMINE DERIVATIVE; CARDIOTONIC AGENT; ENZYME INHIBITOR; ISOQUINOLINE DERIVATIVE; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, RAT; PIPERIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DOWN REGULATION; DRUG EFFICACY; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; ENZYME INHIBITION; EVIDENCE BASED PRACTICE; EXPERIMENTAL LIGATION; EXPERIMENTAL MYOCARDIAL ISCHEMIA; HEART FUNCTION; HEART LEFT ATRIUM; HEART MUSCLE INJURY; HEART PROTECTION; IMMUNOFLUORESCENCE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NICK END LABELING; NONHUMAN; POLYPROPYLENE SUTURE; PROTEIN EXPRESSION; RAT; SINGLE DRUG DOSE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; DRUG EFFECTS; HEART MUSCLE; HEART VENTRICLE FUNCTION; METABOLISM; MYOCARDIAL INFARCTION; PATHOPHYSIOLOGY;

RATTUS; RATTUS NORVEGICUS;

AMIDINES; ANIMALS; APOPTOSIS; BENZYLAMINES; CARDIOTONIC AGENTS; CASPASE 3; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; ISOQUINOLINES; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; NITRIC OXIDE SYNTHASE TYPE II; PIPERIDINES; POLY(ADP-RIBOSE) POLYMERASE INHIBITORS; POLY(ADP-RIBOSE) POLYMERASES; RATS; VENTRICULAR FUNCTION;

EID: 84916623032     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2977     Document Type: Article

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