Scavenging of H2O2 by mouse brain mitochondria

Journal of Bioenergetics and Biomembranes

Volumn 46, Issue 6, 2014, Pages 471-477

  Starkov, Anatoly A ^a   Andreyev, Alexander Yu ^b   Zhang, Steven F ^c   Starkova, Natalia N ^a   Korneeva, Maria ^d   Syromyatnikov, Mikhail ^d   Popov, Vasily N ^d  

^a FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d VORONEZH STATE UNIVERSITY   (Russian Federation)

Author keywords

Hydrogen peroxide; Oxidative stress; Reactive oxygen species; ROS production; ROS removal

Indexed keywords

ADENOSINE DIPHOSPHATE; AURANOFIN; GLUTATHIONE PEROXIDASE 1; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; SUCCINIC ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; DYNAMICS; FLUORESCENCE ANALYSIS; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; SCAVENGING SYSTEM; ANIMAL; BRAIN; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS;

ANIMALS; BRAIN; HYDROGEN PEROXIDE; MICE; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84916598956     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-014-9581-9     Document Type: Article

References (12)

1. Adam-Vizi V, Chinopoulos C (2006) Bioenergetics and the formation of mitochondrial reactive oxygen species. Trends Pharmacol Sci 27(12):639–645. doi:10.1016/j.tips.2006.10.005
2. Andreyev AY, Kushnareva YE, Starkov AA (2005) Mitochondrial metabolism of reactive oxygen species. Biochemistry (Mosc) 70(2):200–214
3. Boveris A, Cadenas E (1997) Cellular sources and steady-state levels of reactive oxygen species. In: Clerch LB, Massaro DJ (eds) Oxygen, gene expression and cellular function. Marcel Dekker, New York, pp 1–25
4. Chance B, Sies H, Boveris A (1979) Hydroperoxide metabolism in mammalian organs. Physiol Rev 59(3):527–605
5. Cox AG, Winterbourn CC, Hampton MB (2010) Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling. Biochem J 425(2):313–325. doi:10.1042/BJ20091541
6. Drechsel DA, Patel M (2010) Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/peroxiredoxin system. J Biol Chem 285(36):27850–27858. doi:10.1074/jbc.M110.101196
7. Hyslop PA, Zhang Z, Pearson DV, Phebus LA (1995) Measurement of striatal H2O2 by microdialysis following global forebrain ischemia and reperfusion in the rat: correlation with the cytotoxic potential of H2O2 in vitro. Brain Res 671(2):181–186
8. Sims NR (1990) Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation. J Neurochem 55(2):698–707
9. Starkov AA (2008) The role of mitochondria in reactive oxygen species metabolism and signaling. Ann N Y Acad Sci 1147:37–52. doi:10.1196/annals.1427.015
10. Starkov AA, Fiskum G (2003) Regulation of brain mitochondrial H2O2 production by membrane potential and NAD (P) H redox state. J Neurochem 86(5):1101–1107
11. Yusa T, Beckman JS, Crapo JD, Freeman BA (1987) Hyperoxia increases H2O2 production by brain in vivo. J Appl Physiol 63(1):353–358
12. Zoccarato F, Cavallini L, Alexandre A (2004) Respiration-dependent removal of exogenous H2O2 in brain mitochondria: inhibition by Ca2+. J Biol Chem 279(6):4166–4174