Plasma levels of soluble fibroblast activation protein in arterial thrombosis; Determinants and cleavage of its substrate alpha-2-antiplasmin

International Journal of Cardiology

Volumn 178, Issue , 2015, Pages 105-110

  Uitte De Willige, Shirley ^a   Malfliet, Joyce J M C ^a   Deckers, Jaap W ^a   Dippel, Diederik W J ^a   Leebeek, Frank W G ^a   Rijken, Dingeman C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Arterial thrombosis; Case control study; Fibroblast activation protein; 2 Antiplasmin

Indexed keywords

ALPHA 2 ANTIPLASMIN; FIBROBLAST ACTIVATION PROTEIN; ORAL CONTRACEPTIVE AGENT; SERINE PROTEINASE; UNCLASSIFIED DRUG; ALPHA-2-ANTIPLASMIN; BIOLOGICAL MARKERS; FIBROBLAST ACTIVATION PROTEIN ALPHA; GELATINASES; MEMBRANE PROTEINS; SERINE ENDOPEPTIDASES;

ADULT; AMINO TERMINAL SEQUENCE; ARTERY THROMBOSIS; ARTICLE; BLOOD SAMPLING; BRAIN ISCHEMIA; CASE CONTROL STUDY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBSTRATE COMPLEX; FEMALE; HORMONAL REGULATION; HUMAN; HYPERLIPIDEMIA; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; ORAL CONTRACEPTIVE USE; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; SEX DIFFERENCE; BLOOD; CASE-CONTROL STUDIES; COHORT STUDIES; CORONARY THROMBOSIS; HUMANS; METABOLISM; MIDDLE AGED; RETROSPECTIVE STUDIES; YOUNG ADULT;

ADULT; ALPHA-2-ANTIPLASMIN; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; COHORT STUDIES; CORONARY THROMBOSIS; FEMALE; GELATINASES; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; RETROSPECTIVE STUDIES; SERINE ENDOPEPTIDASES; YOUNG ADULT;

EID: 84916233938     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.10.091     Document Type: Article

References (17)

1. E.J. Hamson, F.M. Keane, S. Tholen, O. Schilling, and M.D. Gorrell Understanding fibroblast activation protein (FAP): substrates, activities, expression and targeting for cancer therapy Proteomics Clin. Appl. 8 2014 454 463
2. P.J. Collins, G. McMahon, P. O'Brien, and B. O'Connor Purification, identification and characterisation of seprase from bovine serum Int. J. Biochem. Cell Biol. 36 2004 2320 2333
3. K.N. Lee, K.W. Jackson, and V.J. Christiansen Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein Blood 107 2006 1397 1404
4. V.J. Christiansen, K.W. Jackson, K.N. Lee, and P.A. McKee Effect of fibroblast activation protein and alpha(2)-antiplasmin cleaving enzyme on collagen types I, III, and IV Arch. Biochem. Biophys. 457 2007 177 186
5. K.N. Lee, K.W. Jackson, V.J. Christiansen, K.H. Chung, and P.A. McKee A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion Blood 103 2004 3783 3788
6. F.M. Keane, N.A. Nadvi, T.W. Yao, and M.D. Gorrell Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-alpha FEBS J. 278 2011 1316 1332
7. M.T. Levy, G.W. McCaughan, G. Marinos, and M.D. Gorrell Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection Liver 22 2002 93 101
8. S. Uitte de Willige, J.J.M.C. Malfliet, H.L.A. Janssen, F.W.G. Leebeek, and D.C. Rijken Increased N-terminal cleavage of alpha-2-antiplasmin in patients with liver cirrhosis J. Thromb. Haemost. 11 2013 2029 2036
9. C.E. Brokopp, R. Schoenauer, and P. Richards Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata Eur. Heart J. 32 2011 2713 2722
10. J. Tillmanns, C. Widera, and Y. Habbaba Circulating concentrations of fibroblast activation protein alpha in apparently healthy individuals and patients with acute coronary syndrome as assessed by sandwich ELISA Int. J. Cardiol. 168 2013 3926 3931
11. E.L. de Bruijne, A. Gils, and A.H. Guimarães The role of thrombin activatable fibrinolysis inhibitor in arterial thrombosis at a young age: the ATTAC study J. Thromb. Haemost. 7 2009 919 927
12. K.J. Livak Allelic discrimination using fluorogenic probes and the 5′ nuclease assay Genet. Anal. 14 1999 143 149
13. R.B. D'Agostino Sr., R.S. Vasan, and M.J. Pencina General cardiovascular risk profile for use in primary care: the Framingham Heart Study Circulation 117 2008 743 753
14. N. Wild, H. Andres, and W. Rollinger A combination of serum markers for the early detection of colorectal cancer Clin. Cancer Res. 16 2010 6111 6121
15. B. Osborne, T.W. Yao, and X.M. Wang A rare variant in human fibroblast activation protein associated with ER stress, loss of enzymatic function and loss of cell surface localisation Biochim. Biophys. Acta 2014 1844 1248 1259
16. F.M. Keane, T.W. Yao, and S. Seelk Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs FEBS Open Bio 4 2013 43 54
17. V.J. Christiansen, K.W. Jackson, K.N. Lee, and P.A. McKee The effect of a single nucleotide polymorphism on human {alpha}2-antiplasmin activity Blood 109 2007 5286 5292