A mutation in cnot8, component of the Ccr4-Not complex regulating transcript stability, affects expression levels of developmental regulators and reveals a role of FGF3 in development of caudal hypothalamic dopaminergic neurons

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Koch, Peter ^a,b   Löhr, Heiko B ^a,b   Driever, Wolfgang ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR; MESSENGER RNA; CHEMOKINE RECEPTOR CCR4; DOPAMINE; FGF3 PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN;

ANIMAL TISSUE; ARTICLE; CNOT8 GENE; CONTROLLED STUDY; DEADENYLATION DEPENDENT MRNA DECAY; DOPAMINERGIC NERVE CELL; EMBRYO; EMBRYO PATTERN FORMATION; GENE; GENE MUTATION; HYPOTHALAMUS; MOLECULAR CLONING; MUTANT; NERVE CELL DIFFERENTIATION; NONHUMAN; NUCLEIC ACID STRUCTURE, METABOLISM AND FUNCTION; OPEN READING FRAME; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STOP CODON; TRANSCRIPTION REGULATION; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL DIFFERENTIATION; DRUG EFFECTS; EMBRYO DEVELOPMENT; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION;

ANIMALS; CELL DIFFERENTIATION; DOPAMINE; DOPAMINERGIC NEURONS; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; FIBROBLAST GROWTH FACTOR 3; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYPOTHALAMUS; MUTATION; RECEPTORS, CCR4; RNA, MESSENGER; SIGNAL TRANSDUCTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84916233034     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113829     Document Type: Article

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