Young patients (≤35years old) with colorectal cancer have worse outcomes due to more advanced disease: A 30-Year Retrospective Review

Medicine (United States)

Volumn 93, Issue 23, 2014, Pages

  Fu, Jianfei ^a,b   Yang, Jiao ^a,c   Tan, Yinuo ^a,c   Jiang, Mengjie ^a,c   Wen, Fei ^a   Huang, Yanqin ^a   Chen, Hailong ^a   Yi, Chenghao ^a   Zheng, Shu ^a   Yuan, Ying ^c  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE; AGED; CANCER STAGING; COLORECTAL TUMOR; FEMALE; HUMAN; MALE; MIDDLE AGED; MORTALITY; PATHOLOGY; RETROSPECTIVE STUDY; SURVIVAL RATE; TIME; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; RETROSPECTIVE STUDIES; SURVIVAL RATE; TIME FACTORS; YOUNG ADULT;

EID: 84916229753     PISSN: 00257974     EISSN: 15365964     Source Type: Journal    
DOI: 10.1097/MD.0000000000000135     Document Type: Review

References (26)

1. Edwards BK, Ward E, Kohler BA, et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer. 2010;116:544-573
2. You YN, Xing Y, Feig BW, et al. Young-onset colorectal cancer: Is it time to pay attention? Arch Intern Med. 2012;172:287-289
3. Yuan Y, Li MD, Hu HG, et al. Prognostic and survival analysis of 837 Chinese colorectal cancer patients. World J Gastroenterol. 2013;19:2650-2659
4. Hubbard JM, Grothey A. Adolescent and young adult colorectal cancer. J Natl Compr Canc Netw. 2013;11:1219-1225
5. Gilliland FD, Hunt WC, Morris DM, Key CR. Prognostic factors for thyroid carcinoma. A population-based study of 15,698 cases from the Surveillance, Epidemiology and End Results (SEER) program 1973-1991. Cancer. 1997;79:564-573
6. Peres J. Advanced breast cancer in young women. J Natl Cancer Inst. 2013;105:1257-1258
7. Neufeld D, Shpitz B, Bugaev N, et al. Young-age onset of colorectal cancer in Israel. Tech Coloproctol. 2009;13:201-204
8. McMillan DC, Hole DJ, McArdle CS. The impact of old age on cancer-specific and non-cancer-related survival following elective potentially curative surgery for Dukes A/B colorectal cancer. Br J Cancer. 2008;99:1046-1049
9. Chan KK, Dassanayake B, Deen R, et al. Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: Analysis of survival and prognostic markers. World J Surg Oncol. 2010;8:82
10. Kaplan MA, Isikdogan A, Gumus M, et al. Childhood, adolescents, and young adults (
11. O'Connell JB, Maggard MA, Liu JH, et al. Do young colon cancer patients have worse outcomes? World J Surg. 2004;28:558-562
12. Yeo SA, Chew MH, Koh PK, Tang CL. Young colorectal carcinoma patients do not have a poorer prognosis: A comparative review of 2,426 cases. Tech Coloproctol. 2013;17:653-661
13. Taggarshe D, Rehil N, Sharma S, et al. Colorectal cancer: Are the ''young'' being overlooked? Am J Surg. 2013;205:312-316
14. O'Connell JB, Maggard MA, Liu JH, et al. Are survival rates different for young and older patients with rectal cancer? Dis Colon Rectum. 2004;47:2064-2069
15. Chung YF, Eu KW, Machin D, et al. Young age is not a poor prognostic marker in colorectal cancer. Br J Surg. 1998;85:1255-1259
16. Li M, Li JY, Zhao AL, Gu J. Do young patients with colorectal cancer have a poorer prognosis than old patients? J Surg Res. 2011;167:231-236
17. Al-Barrak J, Gill S. Presentation and outcomes of patients aged 30 years and younger with colorectal cancer: A 20-year retrospective review. Med Oncol. 2011;28:1058-1061
18. Ueno H, Mochizuki H, Akagi Y, et al. Optimal colorectal cancer staging criteria in TNM classification. J Clin Oncol. 2012;30:1519-1526
19. O'Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg. 2004;187:343-348
20. Turkiewicz D, Miller B, Schache D, et al. Young patients with colorectal cancer: how do they fare? ANZ J Surg. 2001;71:707-710
21. Mitry E, Benhamiche AM, Jouve JL, et al. Colorectal adenocarcinoma in patients under 45 years of age: Comparison with older patients in a well-defined French population. Dis Colon Rectum. 2001;44:380-387
22. Isbister WH, Fraser J. Large-bowel cancer in the young: A national survival study. Dis Colon Rectum. 1990;33:363-366
23. Dozois EJ, Boardman LA, Suwanthanma W, et al. Young-onset colorectal cancer in patients with no known genetic predisposition: Can we increase early recognition and improve outcome? Medicine (Baltimore). 2008;87:259-263
24. Quah HM, Joseph R, Schrag D, et al. Young age influences treatment but not outcome of colon cancer. Ann Surg Oncol. 2007;14:2759-2765
25. Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer. International Multicentre Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) investigators. J Clin Oncol. 1999;17:1356-1363
26. Quasar Collaborative G,Gray R, Barnwell J, et al. Adjuvant chemotherapy versus observation in patients with colorectal cancer: A randomised studyLancet. 2007;370:2020-2029