Role of steroid hormone receptors in formation and progression of bladder carcinoma: A case-control study

Urology Journal

Volumn 11, Issue 6, 2014, Pages 1968-1973

  Mashhadi, Rahil ^a   Pourmand, Gholamreza ^a   Kosari, Farid ^b   Mehrsai, Abdolrasoul ^a   Salem, Sepehr ^a   Pourmand, Mohammad Reza ^c   Alatab, Sudabeh ^a   Khonsari, Mehdi ^a   Heydari, Fariba ^a   Beladi, Laleh ^a   Alizadeh, Farimah ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Androgen; Biological; Estrogen; Gene expression regulation; Mortality; Neoplasm recurrence; Progesterone; Receptors; Survival rate; Tumor markers; Urinary bladder neoplasms

Indexed keywords

ANDROGEN RECEPTOR; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TUMOR MARKER;

AGED; BLADDER; BLADDER TUMOR; CANCER GRADING; CANCER STAGING; CARCINOMA; EPIDEMIOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; IRAN; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; SURVIVAL RATE; TUMOR RECURRENCE;

AGED; CARCINOMA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; IRAN; MALE; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 84916208761     PISSN: 17351308     EISSN: 1735546X     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Yavari P, Sadrolhefazi B, Mohagheghi MA, Mehrazin R. A descriptive retrospective study of bladder cancer at a hospital in Iran (1973-2003). Asian-Pac J Cancer Prev. 2009;10:681-4.
2. Karimianpour N, Mousavi-Shafaei P, Ziaee AA, et al. Mutations of RAS Gene Family in Specimens of Bladder Cancer. Urol J. 2008;5:237-42.
3. Ploeg M, Aben KK, Kiemeney LA. The present and future burden of urinary bladder cancer in the world. World J Urol. 2009;27:289-93.
4. Nanda MS, Sameer AS, Syeed N, et al. Genetic aberrations of the K-RAS proto-oncogene in bladder cancer in Kashmiri population. Urol J. 2010;7:168-173.
5. Report of National Cancer Registration Iran. Is lamic Republic of Iran. Ministry of Health and Medical Education, Office Health Deputy, Center for Disease Control and Prevention. 2007-2008.
6. Scosyrev E, Noyes K, Feng C, Messing E. Sex and racial differences in bladder cancer presentation and mortality in the US. Cancer. 2009;115:68-74.
7. Miyamoto H, Yao J.L, Chaux A, et al. Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder. BJU Int. 2012;109:1716-26.
8. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics,2010. CA Cancer J Clin. 2010;60:277-300.
9. Bolenz C, Lotan Y, Ashfaq R, Shariat SF. Estrogen and progesterone hormonal receptor expression in urothelial carcinoma of the bladder. Eur Urol. 2009;56:1093-5.
10. Mir C, Shariat SF, Van der Kwast TH, et al. Loss of androgen receptor expression is not associated with pathological stage, grade, gender or outcome in bladder cancer: a large multi-institutional study. BJU Int. 2011;108:24-30.
11. Nam JK, Park SW, Lee SD, Chung MK. Prognostic Value of Sex-Hormone Receptor Expression in Non-Muscle-Invasive Bladder Cancer. Yonsei Med J. 2014;55:1214-21.
12. Miyamoto H, Yang Z, Chen YT, et al. Promotion of bladder cancer development and progression by androgen receptor signals. J Natl Cancer Inst. 2007;99:558-68.
13. McGrath M, Michaud DS, De Vivo I. Hormonal and reproductive factors and the risk of bladder cancer in women. Am J Epidemiol. 2006;163:236.
14. Fortner RT, Eliassen AH, Spiegelman D, Willett WC, Barbieri RL, Hankinson SE. Premenopausal endogenous steroid hormones and breast cancer risk: results from the Nurses'Health Study II. Breast Cancer Research. 2013;15:R19.
15. Chavalmane AK, Comeglio P, Morelli A, et al. Sex steroid receptors in male human bladder: expression and biological function. J Sex Med. 2010;7:2698-713.
16. Liu Z, Li X, Liu S, et al. Flavokawain A inhibits urinary bladder carcinogenesis in the UP II-SV40T transgenic mouse bladder cancer model. Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research. Abstract. 2012;619.
17. Zhuang Y-H, Blauer M, Tammela T, Tuohimaa P. Immunodetection of androgen receptor in human urinary bladder cancer. Histopathology. Histopathology. 1997;30:556-62.
18. Johnson AM, O'Connell MJ, Miyamoto H, et al. Androgenic dependence of exophytic tumor growth in a transgenic mouse model of bladder cancer: a role for thrombospodin-1. B MC. Urol. 2008;8:7.
19. Lamb CA, Helguero LA, Giulianelli S, et al. Antisense oligonucleotides targeting the progesterone receptor inhibit hormone-independent breast cancer growth in mice. Breast Cancer Res. 2005;7:R1111-21.
20. Rahmani AH, Alzohairy M, Babiker AY, Khan AA, Aly SM, Rizvi MA. Implication of androgen receptor in urinary bladder cancer: a critical mini-review. Int J Mol Epidemiol Genet. 2013;4:150-5.
21. Chang C, Lee SO, Yeh S, Chang TM. Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver. Onco gene. 2014;33:3225-34.
22. Li Y, Izumi K, Miyamoto H. The role of the androgen receptor in the development and progression of bladder cancer. Jpn J Clin Oncol. 2012;42:569-77.
23. Shen SS, Smith CL, Hsieh JT, et al. Expression of estrogen receptors-alphaand-betain bladder cancer cell lines and human bladder tumor tissue. Cancer. 2006;106:2610-6.
24. Tuygun C, Kankaya D, Imamoglu A, et al. Sex-specific hormone receptors in urothelial carcinomas of the human urinary bladder: a comparative analysis of clinicopathological features and survival outcomes according to receptor expression. Urol Oncol. 2011;29: 43-51.
25. Epstein JI, Amin MB, Reuter VR, Mostofi FK. The World Health Organization/Inter national Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. Bladder Consensus Conference Committee. Am J Surg Pathol. 1998;22:1435-48.
26. Greene FL, Page DL, Fleming ID, et al. AJCC Cancer Staging Manual, 6th ed. New York (NY): Springer-Verlag, 2002.
27. Boorjian S, Ugras S, Mongan NP, et al. Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer. Urology. 2004;64:383-8.
28. Boorjian SA, Heemers HV, Frank I, et al. Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder. Endocr Relat Cancer. 2009;16:123-37.
29. Kauffman EC, Robinson BD, Downes MJ, et al. Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer. Mol Carcinog. 2011;50:931-44.
30. Kirkali Z, Cowan S, Leake RE. Androgen receptors in transitional cell carcinoma. Int Urol Nephrol. 1990;22:231-4.
31. Ruizeveld de Winter JA, Trapman J, Vermey M, Mulder E, Zegers ND, van der Kwast TH. Androgen receptor expression in human tissues: An immunohistochemical study. J His tochem Cytochem. 1991;39:927-36.
32. Birtle AJ, Freeman A, Munson P. The androgen receptor revisited in urothelial carcinoma. Histopathology. 2004;45:P98-9.
33. Basakci A, Kirkali Z, Tuzel E, Yorukoglu K, Mungan MU, Sade M. Prognostic significance of estrogen receptor expression in superficial transitional cell carcinoma of the urinary bladder. Eur Urol. 2002;41:342-5.