The protective effects of a polyphenol-enriched protein powder on exercise-induced susceptibility to virus infection

Phytotherapy Research

Volumn 28, Issue 12, 2014, Pages 1829-1836

  Ahmed, Maryam ^a   Henson, Dru A ^a   Sanderson, Matthew C ^a   Nieman, David C ^a   Gillitt, Nicholas D ^b   Lila, Mary Ann ^c  

^a APPALACHIAN STATE UNIVERSITY   (United States)

^b Human Performance Laboratory Appalachian State University North Carolina Research Campus ^*  (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Blueberry extract; Green tea; Polyphenols; Virus infection

Indexed keywords

PLACEBO; POLYPHENOL; POLYPHENOL SOY PROTEIN COMPLEX; SOYBEAN PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANTIBACTERIAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BLOOD SAMPLING; BLUEBERRY; CELL PROTECTION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ESCHERICHIA COLI; EXERCISE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INFECTION SENSITIVITY; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; RUNNING; SERUM; STAPHYLOCOCCUS AUREUS; TEA; VESICULAR STOMATITIS VIRUS; VIRUS INFECTION; VIRUS REPLICATION;

VACCINIUM;

EID: 84916204314     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5208     Document Type: Article

References (33)

1. Andrae-Marobela K, Ghislain FW, Okatch H, Majinda, RR. 2013. Polyphenols: a diverse class of multi-target anti-HIV-1 agents. Curr Drug Metab 14(4):392-413.
2. Brown AS, Davis JM, Murphy EA, et al. (2007). Susceptibility to HSV-1 infection and exercise stress in female mice: role of estrogen. J Appl Physiol (1985) 103(5):1592-7.
3. Calland N, Albecka A, Belouzard S, et al. 2012. (-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry. Hepatology 55(3):720-9.
4. Carneiro FA, Bianconi ML, Weissmuller G, Stauffer F, Da Poian AT. 2002. Membrane recognition by vesicular stomatitis virus involves enthalpy-driven protein-lipid interactions. J Virol 76(8):3756-64.
5. Cushnie TP, Lamb AJ. 2005. Antimicrobial activity of flavonoids. Int J Antimicrob Agents 26(5):343-56.
6. Daglia M. 2012. Polyphenols as antimicrobial agents. Curr Opin Biotechnol 23(2):174-81.
7. Davis JM, Murphy EA, Brown AS, Carmichael MD, Ghaffar A, Mayer EP. 2004. Effects of oat beta-glucan on innate immunity and infection after exercise stress. Med Sci Sports Exerc 36(8):1321-7.
8. Del Rio D, Rodriguez-Mateos A, Spencer JP, Tognolini M, Borges G, Crozier A. 2013. Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal 18(14):1818-92.
9. Ekblom B, Ekblom O, Malm C. 2006. Infectious episodes before and after a marathon race. Scand J Med Sci Sports 16(4):287-93.
10. Fioravanti R, Celestino I, Costi R, et al. 2012. Effects of polyphenol compounds on influenza A virus replication and definition of theirmechanism of action. Bioorg Med Chem 20(16):5046-52.
11. Gonzalez-Vallinas M, Gonzalez-Castejon M, Rodriguez-Casado A, Ramirez De Molina A. 2013. Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives. Nutr Rev 71(9):585-99.
12. Guay DR. 2009. Cranberry and urinary tract infections. Drugs 69(7):775-807.
13. Johannsdottir HK, Mancini R, Kartenbeck J, Amato L, Helenius A. 2009. Host cell factors and functions involved in vesicular stomatitis virus entry. J Virol 83(1):440-53.
14. Khurana S, Piche M, Hollingsworth A, Venkataraman K, Tai TC. 2013. Oxidative stress and cardiovascular health: therapeutic potential of polyphenols. Can J Physiol Pharmacol 91(3):198-212.
15. Kim Y, Narayanan S, Chang KO. 2010. Inhibition of influenza virus replication by plant-derived isoquercetin. Antiviral Res 88(2):227-35.
16. Kim M, Kim SY, Lee HW, et al. 2013. Inhibition of influenza virus internalization by (-)-epigallocatechin-3-gallate. Antiviral Res 100(2):460-72.
17. Kopecky SA, Willingham MC, Lyles DS. 2001. Matrix protein and another viral component contribute to induction of apoptosis in cells infected with vesicular stomatitis virus. J Virol 75:12169-12181.
18. Landete JM. 2012. Updated knowledge about polyphenols: functions, bioavailability, metabolism, and health. Crit Rev Food Sci Nutr 52(10):936-48.
19. Li D, Baert L, Uyttendaele M. 2013. Inactivation of food-borne viruses using natural biochemical substances. Food Microbiol 35(1):1-9.
20. Martin SA, Pence BD, Woods JA. 2009. Exercise and respiratory tract viral infections. Exerc Sport Sci Rev 37(4):157-64.
21. Murphy EA, Davis JM, Brown AS, et al. 2004. Role of lung macrophages on susceptibility to respiratory infection following short-term moderate exercise training. Am J Physiol Regul Integr Comp Physiol 287(6):R1354-8.
22. Murphy EA, Davis JM, Carmichael MD, Gangemi JD, Ghaffar A, Mayer EP. 2008. Exercise stress increases susceptibility to influenza infection. Brain Behav Immun 22(8):1152-5.
23. Nieman DC. 1994. Exercise, upper respiratory tract infection, and the immune system. Med Sci Sports Exerc 26(2):128-39.
24. Nieman DC, Johanssen LM, Lee JW. 1989. Infectious episodes in runners before and after a roadrace. J Sports Med Phys Fitness 29(3):289-96.
25. Nieman DC, Johanssen LM, Lee JW, Arabatzis K. 1990. Infectious episodes in runners before and after the Los Angeles Marathon. J Sports Med Phys Fitness 30(3):316-28.
26. Nieman, DC, Gillitt, ND, Knab, AM, et al. 2013. Influence of a polyphenol-enriched protein powder on exercise-induced inflammation and oxidative stress in athletes: a randomized trial using a metabolomics approach. PLoS One 8(8):e72215.
27. Powers SK, Jackson MJ. 2008. Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev 88(4):1243-76.
28. Roopchand DE, Grace MH, Kuhn P, et al. 2012. Efficient sorption of polyphenols to soybean flour enables natural fortification of foods. Food Chem 131(4):1193-1200.
29. Selway JW. 1986. Antiviral activity of flavones and flavans. Prog Clin Biol Res 213:521-36.
30. Steinmann J, Buer J, Pietschmann T, Steinmann E. 2013. Antiinfective properties of epigallocatechin-3-gallate (EGCG), a component of green tea. Br J Pharmacol 168(5):1059-73.
31. Swaminathan K, Dyason JC, Maggioni A, Von Itzstein M, Downard KM. 2013. Binding of a natural anthocyanin inhibitor to influenza neuraminidase by mass spectrometry. Anal Bioanal Chem 405(20):6563-72.
32. Whitlow ZW, Connor JH, Lyles DS. 2006. Preferential translation of vesicular stomatitis virus mRNAs is conferred by transcription from the viral genome. J Virol 80(23):11733-42.
33. Zafra-Stone S, Yasmin T, Bagchi M, Chatterjee A, Vinson JA, Bagchi D. 2007. Berry anthocyanins as novel antioxidants in human health and disease prevention. Mol Nutr Food Res 51(6):675-83.