Bidirectional links between HIV and intimate partner violence in pregnancy: Implications for prevention of mother-to-child transmission

Journal of the International AIDS Society

Volumn 17, Issue , 2014, Pages

  Hatcher, Abigail M ^a,b   Woollett, Nataly ^a   Pallitto, Christina C ^c   Mokoatle, Keneuoe ^a   Stöckl, Heidi ^d   MacPhail, Catherine ^a,e   Delany Moretlwe, Sinead ^a   García Moreno, Claudia ^c  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WORLD HEALTH ORGANIZATION   (Switzerland)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^e UNIVERSITY OF NEW ENGLAND   (Australia)

Author keywords

Adherence; HIV; Intimate partner violence; Pregnancy; Prevention of mother to child transmission

Indexed keywords

ADULT; AFRICA SOUTH OF THE SAHARA; ARTICLE; CHILD; CLINICAL ARTICLE; DOMESTIC VIOLENCE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; PARTNER VIOLENCE; PREGNANCY; PREGNANT WOMAN; PRENATAL CARE; QUALITATIVE RESEARCH; SECONDARY PREVENTION; VERTICAL TRANSMISSION; VIRUS TRANSMISSION; HEALTH CARE DELIVERY; HIV INFECTIONS; INFANT; INTERVIEW; MALE; NEWBORN; PREGNANCY COMPLICATIONS, INFECTIOUS; PREVENTION AND CONTROL; SEXUAL CRIME; SOUTH AFRICA; TRANSMISSION;

FEMALE; HEALTH SERVICES ACCESSIBILITY; HIV INFECTIONS; HUMANS; INFANT; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; INTERVIEWS AS TOPIC; MALE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; SEX OFFENSES; SOUTH AFRICA;

EID: 84915819182     PISSN: None     EISSN: 17582652     Source Type: Journal    
DOI: 10.7448/IAS.17.1.19233     Document Type: Article

References (76)

1. Coutsoudis A, Pillay K, Spooner E, Kuhn L, Coovadia HM. Influence of infantfeeding patterns on early mother-to-child transmission of HIV-1 in Durban, South Africa: a prospective cohort study. South African Vitamin A Study Group. Lancet. 1999;354:471-6.
2. Miotti PG, Taha TE, Kumwenda NI, Broadhead R, Mtimavalye LA, Van der Hoeven L, et al. HIV transmission through breastfeeding: a study in Malawi. JAMA. 1999;282:744-9.
3. Lehman DA, John-Stewart GC, Overbaugh J. Antiretroviral strategies to prevent mother-to-child transmission of HIV: striking a balance between efficacy, feasibility, and resistance. PLoS Med. 2009;6:e1000169.
4. Mofenson LM. Protecting the next generation-eliminating perinatal HIV-1 infection. N Engl J Med. 2010;362:2316-8.
5. WHO, UNICEF, UNAIDS. Global update on HIV treatment 2013: results, impact and opportunities. Geneva: World Health Organization; 2013.
6. Nachega JB, Uthman OA, Anderson J, Peltzer K, Wampold S, Cotton MF, et al. Adherence to antiretroviral therapy during and after pregnancy in low-income, middle-income, and high-income countries: a systematic review and meta-analysis. AIDS. 2012;26:2039-52.
7. World Health Organization. Antiretroviral drugs for treating pregnant women and prevention HIV infection in infants: recommendations for a public health approach. Geneva: WHO; 2010.
8. Turan JM, Nyblade L. HIV-related stigma as a barrier to achievement of global PMTCTand maternal health goals: a review of the evidence. AIDS Behav. 2013;17:2528-39.
9. Bond V, Chase E, Aggleton P. Stigma, HIV/AIDS and prevention of mother-to-child transmission in Zambia. Eval Program Plann. 2002;25:347-56.
10. Bwirire LD, Fitzgerald M, Zachariah R, Chikafa V, Massaquoi M, Moens M, et al. Reasons for loss to follow-up among mothers registered in a prevention-of-mother-to-child transmission program in rural Malawi. Trans Roy Soc Trop Med Hyg. 2008;102:1195-200.
11. Mepham S, Zondi Z, Mbuyazi A, Mkhwanazi N, Newell ML. Challenges in PMTCT antiretroviral adherence in northern KwaZulu-Natal, South Africa. AIDS Care. 2011;23:741-7.
12. Turan JM, Bukusi EA, Onono M, Holzemer WL, Miller S, Cohen CR. HIV/AIDS stigma and refusal of HIV testing among pregnant women in rural Kenya: results from the MAMAS Study. AIDS Behav. 2011;15:1111-20.
13. Watts C, Zimmerman C, Eckhaus T, Nyblade L. Modelling the impact of stigma on HIV and AIDS programmes: preliminary projections for mother-to-child transmission. Washington, DC: International Center for Research on Women, London School of Hygiene & Tropical Medicine; 2010.
14. Antelman G, Smith Fawzi MC, Kaaya S, Mbwambo J, Msamanga GI, Hunter DJ, et al. Predictors of HIV-1 serostatus disclosure: a prospective study among HIV-infected pregnant women in Dar es Salaam, Tanzania. AIDS. 2001;15:1865-74.
15. Kilewo C, Massawe A, Lyamuya E, Semali I, Kalokola F, Urassa E, et al. HIV counseling and testing of pregnant women in sub-Saharan Africa: experiences from a study on prevention of mother-to-child HIV-1 transmission in Dar es Salaam, Tanzania. J Acquir Immune Defic Syndr. 2001;28:458-62.
16. Medley A, Garcia-Moreno C, McGill S, Maman S. Rates, barriers and outcomes of HIV serostatus disclosure among women in developing countries: implications for prevention of mother-to-child transmission programmes. Bull World Health Organ. 2004;82:299-307.
17. Pool R, Nyanzi S, Whitworth JA. Attitudes to voluntary counselling and testing for HIV among pregnant women in rural south-west Uganda. AIDS Care. 2001;13:605-15.
18. Bajunirwe F, Muzoora M. Barriers to the implementation of programs for the prevention of mother-to-child transmission of HIV: a cross-sectional survey in rural and urban Uganda. AIDS Res Ther. 2005;2:10.
19. Tchendjou PT, Koki PN, Eboko F, Malateste K, Essounga AN, Amassana D, et al. Factors associated with history of HIV testing among pregnant women and their partners in Cameroon: baseline data from a Behavioral Intervention Trial (ANRS 12127 Prenahtest). J Acquir Immune Defic Syndr. 2011;57(Suppl 1):S9-15.
20. Maman S, Moodley D, Groves AK. Defining male support during and after pregnancy from the perspective of HIV-positive and HIV-negative women in Durban, South Africa. J Midwifery Women's Health. 2011;56:325-31.
21. Turan JM, Hatcher AH, Medema-Wijnveen J, Onono M, Miller S, Bukusi EA, et al. The role of HIV-related stigma in utilization of skilled childbirth services in rural Kenya: a prospective mixed-methods study. PLoS Med. 2012;9:e1001295.
22. Hatcher AM, Turan JM, Leslie HH, Kanya LW, Kwena Z, Johnson MO, et al. Predictors of linkage to care following community-based HIV counseling and testing in rural Kenya. AIDS Behav. 2011;16(5):1295-307.
23. Cohen MH, Cook JA, Grey D, Young M, Hanau LH, Tien P, et al. Medically eligible women who do not use HAART: the importance of abuse, drug use, and race. Am J Public Health. 2004;94:1147-51.
24. Jones AS, Lillie-Blanton M, Stone VE, Ip EH, Zhang Q, Wilson TE, et al. Multi-dimensional risk factor patterns associated with non-use of highly active antiretroviral therapy among human immunodeficiency virus-infected women. Womens Health Issues. 2010;20:335-42.
25. Siemieniuk RA, Krentz HB, Gish JA, Gill MJ. Domestic violence screening: prevalence and outcomes in a Canadian HIV population. AIDS Patient Care STDS. 2010;24:763-70.
26. Peltzer K, Sikwane E, Majaja M. Factors associated with short-course antiretroviral prophylaxis (dual therapy) adherence for PMTCT in Nkangala district, South Africa. Acta Paediatr. 2010;100:1253-7.
27. Aluisio A, Richardson BA, Bosire R, John-Stewart G, Mbori-Ngacha D, Farquhar C. Male antenatal attendance and HIV testing are associated with decreased infant HIV infection and increased HIV-free survival. J Acquir Immune Defic Syndr. 2011;56:76-82.
28. National Department of Health. The National Antenatal Sentinel HIV and Syphilis Prevalence Survey. Johannesburg, South Africa: National Department of Health; 2012.
29. Groves AK, Kagee A, Maman S, Moodley D, Rouse P. Associations between intimate partner violence and emotional distress among pregnant women in Durban, South Africa. J Interpers Violence. 2012;27:1341-56.
30. Hoque ME, Hoque M, Kader SB. Prevalence and experience of domestic violence among rural pregnant women in KwaZulu-Natal, South Africa. South Afr J Epidemiol Infect. 2009;24:34-7.
31. Mbokota M, Moodley J. Domestic abuse-an antenatal survey at King Edward VIII Hospital, Durban. S Afr Med J. 2003;93:455-7.
32. Dunkle KL, Jewkes RK, Brown HC, Yoshihama M, Gray GE, McIntyre JA, et al. Prevalence and patterns of gender-based violence and revictimization among women attending antenatal clinics in Soweto, South Africa. Am J Epidemiol. 2004;160:230-9.
33. Montgomery CM, Watts C, Pool R. HIV and dyadic intervention: an interdependence and communal coping analysis. PLoS One. 2012;7:e40661.
34. Hirsch JS. Gender, sexuality, and antiretroviral therapy: using social science to enhance outcomes and inform secondary prevention strategies. AIDS. 2007;21(Suppl 5):S21-9.
35. Heise LL. Violence against women an integrated, ecological framework. Violence Against Women. 1998;4:262-90.
36. WHO. Putting women first: ethical and safety recommendations for research on domestic violence against women. Geneva, Switzerland: Department of Gender and Women's Health, World Health Organisation; 2001.
37. Miles M, Huberman A. Qualitative data analysis: an expanded sourcebook. Thousand Oaks, CA: Sage Press; 1994.
38. Hutchison AJ, Johnston LH, Breckon JD. Using QSR-NVivo to facilitate the development of a grounded theory project: an account of a worked example. Int J Soc Res Methodol. 2010;13:283-302.
39. Lopez EJ, Jones DL, Villar-Loubet OM, Arheart KL, Weiss SM. Violence, coping, and consistent medication adherence in HIV-positive couples. AIDS Educ Prev. 2010;22:61-8.
40. Rose RC, House AS, Stepleman LM. Intimate partner violence and its effects on the health of African American HIV-positive women. Psychol Trauma. 2010;2:311-7.
41. Trimble DD, Nava A, McFarlane J. Intimate partner violence and antiretroviral adherence among women receiving care in an urban Southeastern Texas HIV clinic. J Assoc Nurses AIDS Care. 2013;24:331-40.
42. Zierler S, Cunningham WE, Andersen R, Shapiro MF, Nakazono T, Morton S, et al. Violence victimization after HIV infection in a US probability sample of adult patients in primary care. Am J Public Health. 2000;90:208-15.
43. Connors NC, Schechter GE, Weber KM, Young MA, Schwartz RM. Psychosocial factors associated with gender-based violence and antiretroviral adherence among HIV-positive women in a New York City clinic. 19th International AIDS Conference. Washington, DC; 2012.
44. Awiti Ujiji O, Ekstrom AM, Ilako F, Indalo D, Wamalwa D, Rubenson B. Reasoning and deciding PMTCT-adherence during pregnancy among women living with HIV in Kenya. Cult Health Sex. 2011;13:829-40.
45. Gourlay A, Birdthistle I, Mburu G, Iorpenda K, Wringe A. Barriers and facilitating factors to the uptake of antiretroviral drugs for prevention of mother-to-child transmission of HIV in sub-Saharan Africa: a systematic review. J Int AIDS Soc. 2013;16:18588.
46. Ezechi OC, Gab-Okafor C, Onwujekwe DI, Adu RA, Amadi E, Herbertson E. Intimate partner violence and correlates in pregnant HIV positive Nigerians. Arch Gynecol Obstet. 2009;280:745-52.
47. Shamu S, Zarowsky C, Shefer T, Temmerman M, Abrahams N. Intimate partner violence after disclosure of HIV test results among pregnant women in Harare, Zimbabwe. PLoS One. (in press).
48. Desgrees-du-Lou A, Brou H, Traore AT, Djohan G, Becquet R, Leroy V From prenatal HIV testing of the mother to prevention of sexual HIV transmission within the couple. Soc Sci Med. 2009;69:892-9.
49. Orne-Gliemann J, Desgrees-Du-Lou A. The involvement of men within prenatal HIV counselling and testing. Facts, constraints and hopes. AIDS. 2008;22:2555-7.
50. Katz DA, Kiarie JN, John-Stewart GC, Richardson BA, John FN, Farquhar C. HIV testing men in the antenatal setting: understanding male non-disclosure. Int J STD AIDS. 2009;20:765-7.
51. Bond VA. "It is not an easy decision on HIV, especially in Zambia": opting for silence, limited disclosure and implicit understanding to retain a wider identity. AIDS Care. 2010;22(Suppl 1):6-13.
52. Farquhar C, Kiarie JN, Richardson BA, Kabura MN, John FN, Nduati RW, et al. Antenatal couple counseling increases uptake of interventions to prevent HIV-1 transmission. J Acquir Immune Defic Syndr. 2004;37:1620-6.
53. Urquia ML, O'Campo PJ, Heaman MI, Janssen PA, Thiessen KR. Experiences of violence before and during pregnancy and adverse pregnancy outcomes: an analysis of the Canadian Maternity Experiences Survey. BMC Pregnancy Childbirth. 2011;11:42.
54. Beydoun HA, Beydoun MA, Kaufman JS, Lo B, Zonderman AB. Intimate partner violence against adult women and its association with major depressive disorder, depressive symptoms and postpartum depression: a systematic review and meta-analysis. Soc Sci Med. 2012;75:959-75.
55. Murray LK, Haworth A, Semrau K, Singh M, Aldrovandi GM, Sinkala M, et al. Violence and abuse among HIV-infected women and their children in Zambia: a qualitative study. J Nerv Ment Dis. 2006;194:610-5.
56. Gielen AC, Ghandour RM, Burke JG, Mahoney P, McDonnell KA, O'Campo P, et al. HIV/AIDS and intimate partner violence: intersecting women's health issues in the United States. Trauma Violence Abuse. 2007;8:178-98.
57. Ammassari A, Antinori A, Aloisi MS, Trotta MP, Murri R, Bartoli L, et al. Depressive symptoms, neurocognitive impairment, and adherence to highly active antiretroviral therapy among HIV-infected persons. Psychosomatics. 2004;45:394-402.
58. Cook JA, Cohen MH, Burke J, Grey D, Anastos K, Kirstein L, et al. Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women. J Acquir Immune Defic Syndr. 2002;30:401-9.
59. Starace F, Ammassari A, Trotta MP, Murri R, De Longis P, Izzo C, et al. Depression is a risk factor for suboptimal adherence to highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2002;31(Suppl 3):S136-9.
60. Sumari-de Boer IM, Sprangers MA, Prins JM, Nieuwkerk PT. HIV stigma and depressive symptoms are related to adherence and virological response to antiretroviral treatment among immigrant and indigenous HIV infected patients. AIDS Behav. 2012;16:1681-9.
61. Antelman G, Kaaya S, Wei R, Mbwambo J, Msamanga GI, Fawzi WW, et al. Depressive symptoms increase risk of HIV disease progression and mortality among women in Tanzania. J Acquir Immune Defic Syndr. 2007;44:470-7.
62. Malow R, Devieux JG, Stein JA, Rosenberg R, Jean-Gilles M, Attonito J, et al. Depression, substance abuse and other contextual predictors of adherence to antiretroviral therapy (ART) among Haitians. AIDS Behav. 2013; 17:1221-30.
63. Rochat TJ, Tomlinson M, Barnighausen T, Newell ML, Stein A. The prevalence and clinical presentation of antenatal depression in rural South Africa. J Affect Disord. 2011;135:362-73.
64. Honikman S, van Heyningen T, Field S, Baron E, Tomlinso M. Stepped care for maternal mental health: a case study of the perinatal mental health project in South Africa. PLoS Med. 2012;9:e1001222.
65. Colebunders RL, Myer L. Antiretrovirals during pregnancy: a note of caution. J Infect Dis. 2013;208:706-7.
66. Cooper ER, Charurat M, Mofenson L, Hanson IC, Pitt J, Diaz C, et al. Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. J Acquir Immune Defic Syndr. 2002;29:484-94.
67. Zeh C, Weidle PJ, Nafisa L, Lwamba HM, Okonji J, Anyango E, et al. HIV-1 drug resistance emergence among breastfeeding infants born to HIV-infected mothers during a single-arm trial of triple-antiretroviral prophylaxis for prevention of mother-to-child transmission: a secondary analysis. PLoS Med. 2011;8:e1000430.
68. Wingood GM, DiClemente RJ. The effects of an abusive primary partner on the condom use and sexual negotiation practices of African-American women. Am J Public Health. 1997;87:1016-8.
69. Shamu S, Abrahams N, Temmerman M, Zarowsky C. Opportunities and obstacles to screening pregnant women for intimate partner violence during antenatal care in Zimbabwe. Cult Health Sex. 2013;15:511-24.
70. Bacchus L, Mezey G, Bewley S, Hawort A. Prevalence of domestic violence when midwives routinely enquire in pregnancy. BJOG. 2004;111:441-5.
71. WHO. Responding to intimate partner violence and sexual violence against women: WHO clinical and policy guidelines. Geneva: World Health Organization; 2013.
72. Christofides N, Jewkes R. Acceptability of universal screening for intimate partner violence in voluntary HIV testing and counseling services in South Africa and service implications. AIDS Care. 2010;22:279-85.
73. Joyner K, Mash R. Recognizing intimate partner violence in primary care: Western Cape, South Africa. PLoS One. 2012;7:e29540.
74. Morse JM. Critical issues in qualitative research methods. Sage Publications, Incorporated. 1993.
75. Woollett N, Hatcher A, Pallitto C, Garcia-Moreno C. Safe & sound study DOH-27-0414-4720. Johannesburg: Department of Health, South African Clinical Trials Registry; 2014.
76. Gopalappa C, Stover J, Shaffer N, Mahy M. The costs and benefits of Option B+ for the prevention of mother-to-child transmission of HIV. AIDS. 2014;28(Suppl 1):S5-14.