A new complex of curcumin with sulfobutylether-β-cyclodextrin: Characterization studies and in vitro evaluation of cytotoxic and antioxidant activity on HepG-2 cells

Journal of Pharmaceutical Sciences

Volumn 103, Issue 12, 2014, Pages 3932-3940

  Cutrignelli, Annalisa ^a   Lopedota, Angela ^a   Denora, Nunzio ^a   Iacobazzi, Rosa Maria ^a,b   Fanizza, Elisabetta ^a,c   Laquintana, Valentino ^a   Perrone, Mara ^a   Maggi, Vito ^a   Franco, Massimo ^a  

^a UNIVERSITY OF BARI   (Italy)

^b NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

^c CNR   (Italy)

Author keywords

Antioxidant activity; Cell culture; Complexation; Curcumin; Cytotoxicity; Solid state; Solubility; Sulfobutylether cyclodextrin; UV VIS spectroscopy

Indexed keywords

BETA CYCLODEXTRIN SULFOBUTYL ETHER; CURCUMIN; DOXORUBICIN; ANTIOXIDANT; BETA CYCLODEXTRIN DERIVATIVE; SBE4-BETA-CYCLODEXTRIN; SOLUTION AND SOLUBILITY;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; FREEZE DRYING; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIMIT OF DETECTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SOLID STATE; STOICHIOMETRY; BIOAVAILABILITY; CHEMISTRY; DRUG FORMULATION; PHARMACOLOGY; PROCEDURES; SOLUBILITY; SOLUTION AND SOLUBILITY; TUMOR CELL LINE;

ANTIOXIDANTS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CELL LINE, TUMOR; CURCUMIN; DRUG COMPOUNDING; FREEZE DRYING; HEP G2 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PHARMACEUTICAL SOLUTIONS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84915775627     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24200     Document Type: Article

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