Post-translational dual regulation of cytochrome P450 aromatase at the catalytic and protein levels by phosphorylation/dephosphorylation

FEBS Journal

Volumn 281, Issue 21, 2014, Pages 4830-4840

  Hayashi, Takanori ^a   Harada, Nobuhiro ^a  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aromatase; Calcineurin; Calcium calmodulin kinase II; Phosphorylation; Post translational regulation

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; AROMATASE; CALCINEURIN; CALCINEURIN INHIBITOR; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLOHEXIMIDE; CYCLOSPORIN A; MAGNESIUM; MESSENGER RNA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; REAGENT; SMALL INTERFERING RNA; TACROLIMUS; CYCLOSPORIN; CYP19A1 PROTEIN, HUMAN; HYBRID PROTEIN; PROTEIN KINASE INHIBITOR; TUMOR PROTEIN;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME RECONSTITUTION; ENZYME REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; MICROSOME; PROTEIN DEPHOSPHORYLATION; PROTEIN PROCESSING; ANTAGONISTS AND INHIBITORS; CELL FREE SYSTEM; CHORIOCARCINOMA; CYTOSOL; DRUG EFFECTS; ENZYMOLOGY; FEMALE; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN DEGRADATION; RNA INTERFERENCE; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; AROMATASE; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CATALYSIS; CELL LINE, TUMOR; CELL-FREE SYSTEM; CHORIOCARCINOMA; CYCLOSPORINE; CYTOSOL; FEMALE; HUMANS; MAGNESIUM; MICROSOMES; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TACROLIMUS;

EID: 84915767022     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13021     Document Type: Article

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