Detection of adventitious agents using next-generation sequencing

PDA Journal of Pharmaceutical Science and Technology

Volumn 68, Issue 6, 2014, Pages 651-660

  Richards, Brenda ^a   Cao, Sherry ^a   Plavsic, Mark ^a   Pomponio, Robert ^a   Davies, Claire ^a   Mattaliano, Robert ^a   Madden, Stephen ^a   Klinger, Katherine ^a   Palermo, Adam ^a  

^a SANOFI   (France)

Author keywords

Adventitious agents; Biosurveillance; Library construction; Limit of detection; Next generation sequencing

Indexed keywords

ADENOVIRUS VECTOR; DOUBLE STRANDED DNA; LENTIVIRUS VECTOR; PARVOVIRUS VECTOR; RNA; SINGLE STRANDED DNA; BACTERIAL DNA; BIOLOGICAL PRODUCT; VIRUS DNA; VIRUS RNA;

ANIMAL CELL; BACILLUS CEREUS; BACTERIOPHAGE; BACTERIOPHAGE M13; BACTERIOPHAGE QBETA; BACTERIUM; BACTERIUM DETECTION; BIOREACTOR; CALICIVIRUS; CHO CELL LINE; CONFERENCE PAPER; CONTROLLED STUDY; DILUTION CURVE; DNA VIRUS; LIMIT OF DETECTION; MS2 VIRUS; NEXT GENERATION SEQUENCING; NONHUMAN; NUCLEOTIDE SEQUENCE; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; RNA SEQUENCE; RNA VIRUS; SEQUENCE ANALYSIS; STAPHYLOCOCCUS EPIDERMIDIS; VESIVIRUS; VIRUS DETECTION; VIRUS GENOME; ANIMAL; CELL CULTURE TECHNIQUE; CRICETULUS; DRUG CONTAMINATION; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN; MICROBIOLOGICAL EXAMINATION; PHARMACEUTICS; PREVENTION AND CONTROL; PROCEDURES; STANDARD; STANDARDS; VIROLOGY; VIRUS;

ANIMALS; BACTERIA; BACTERIOLOGICAL TECHNIQUES; BIOLOGICAL PRODUCTS; BIOPHARMACEUTICS; BIOREACTORS; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETULUS; DNA, BACTERIAL; DNA, VIRAL; DRUG CONTAMINATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LIMIT OF DETECTION; REFERENCE STANDARDS; RNA, VIRAL; VIROLOGY; VIRUSES;

EID: 84915757071     PISSN: 10797440     EISSN: 19482124     Source Type: Journal    
DOI: 10.5731/pdajpst.2014.01025     Document Type: Conference Paper

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