Identification and quantitation of vesivirus 2117 particles in bioreactor fluids from infected Chinese hamster ovary cell cultures

Biotechnology and Bioengineering

Volumn 110, Issue 5, 2013, Pages 1342-1353

  Qiu, Yongchang ^a   Jones, Nathan ^a   Busch, Michelle ^a   Pan, Peng ^a   Keegan, Jesse ^a   Zhou, Weichang ^a   Plavsic, Mark ^a   Hayes, Michael ^a   Mcpherson, John M ^a   Edmunds, Tim ^a   Zhang, Kate ^a   Mattaliano, Robert J ^a  

^a GENZYME CORPORATION   (United States)

Author keywords

CHO cells; Mass spectrometry; Protein profiling; RT PCR; Vesivirus 2117; Viral particles

Indexed keywords

CHO CELL; PROTEIN PROFILING; RT-PCR; VESIVIRUS 2117; VIRAL PARTICLES;

BIOCONVERSION; BIOREACTORS; CELL CULTURE; ELECTRON MICROSCOPY; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLANT SHUTDOWNS; PRODUCTION ENGINEERING; VIRUSES;

PEPTIDES;

CAPSID PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BIOREACTOR EQUIPMENT; BIOREACTOR FLUID; CELL CULTURE; CHO CELL; CONTROLLED STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VESIVIRUS; VIRAL CONTAMINATION; VIRUS GENOME; VIRUS IDENTIFICATION; VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CHO CELLS; CHROMATOGRAPHY, ION EXCHANGE; CRICETINAE; CRICETULUS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; RNA, VIRAL; TANDEM MASS SPECTROMETRY; VESIVIRUS; VIRAL PROTEINS; VIRION;

CRICETULUS GRISEUS; MIRIDAE; VESIVIRUS;

EID: 84875539003     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24791     Document Type: Article

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