Robust and precise morphogen-mediated patterning: Trade-offs, constraints and mechanisms

Journal of the Royal Society Interface

Volumn 12, Issue 102, 2015, Pages

  Lo, Wing Cheong ^a,b   Zhou, Shaohua ^c   Wan, Frederic Y M ^c   Lander, Arthur D ^c   Nie, Qing ^c  

^a OHIO STATE UNIVERSITY   (United States)

^b CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Morphogen; Robustness; Tissue patterning

Indexed keywords

BIOSYNTHESIS; CELL MEMBRANES; CELL SIGNALING; CHELATION; COMMERCE; GENE EXPRESSION; ROBUSTNESS (CONTROL SYSTEMS); TISSUE;

ACCURACY AND PRECISION; BINDING MOLECULES; CELL-TO-CELL VARIABILITY; ENVIRONMENTAL PERTURBATIONS; MORPHOGEN; MORPHOGEN GRADIENTS; PERFORMANCE OBJECTIVE; POTENTIAL MECHANISM;

ECONOMIC AND SOCIAL EFFECTS;

GLYPICAN; MORPHOGEN; SYNDECAN;

ACCURACY; ARTICLE; BINDING SITE; CELL SURFACE; DIFFUSION; DROSOPHILA; FORELIMB; GENE CONTROL; GENE EXPRESSION; IMAGINAL DISC; LIGAND BINDING; NONHUMAN; PROTEIN SYNTHESIS; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; STEADY STATE; ALGORITHM; ANIMAL; BIOLOGICAL MODEL; CALIBRATION; GENE EXPRESSION REGULATION; MORPHOGENESIS; PHYSIOLOGY; THEORETICAL MODEL; WING;

ALGORITHMS; ANIMALS; BODY PATTERNING; CALIBRATION; DROSOPHILA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MODELS, BIOLOGICAL; MODELS, THEORETICAL; MORPHOGENESIS; SIGNAL TRANSDUCTION; WINGS, ANIMAL;

EID: 84915748173     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.1041     Document Type: Article

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