2, 3-dimercaptosuccinic acid-modified iron oxide clusters for magnetic resonance imaging

Journal of Pharmaceutical Sciences

Volumn 103, Issue 12, 2014, Pages 4030-4037

  Xiong, Fei ^a   Yan, Caiyun ^a   Tian, Jilai ^a   Geng, Kunkun ^a   Zhu, Ziyi ^a   Song, Lina ^a   Zhang, Y U ^a   Mulvale, Matthew ^b   Gu, Ning ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Biodistribution; Formulation; Liver targeting; Lyophilization; MRI; Nanotechnology; Pharmacokinetics; Stability; Superparamagnetic iron oxide nanoparticles (SPION)

Indexed keywords

2,3 DIMERCAPTOSUCCINIC ACID MODIFIED MAGHEMITE NANOPARTICLE; GADOLINIUM PENTETATE MEGLUMINE; MAGNETITE NANOPARTICLE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; SUCCIMER; SUPERPARAMAGNETIC IRON OXIDE; UNCLASSIFIED DRUG; CONTRAST MEDIUM; FERRIC ION; FERRIC OXIDE; NANOPARTICLE; POWDER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BIOCOMPATIBILITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; DRUG UPTAKE; ELIMINATION HALF-LIFE; ELIMINATION RATE CONSTANT; EXPERIMENTAL RABBIT; FREEZE DRYING; IN VIVO STUDY; LIVER; MACROPHAGE; MALE; MEAN RESIDENCE TIME; MOLECULAR STABILITY; MOUSE; NANOTOXICOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; POWDER; RETICULOENDOTHELIAL SYSTEM; TARGET ORGAN; ANIMAL; CELL LINE; CHEMISTRY; DRUG STABILITY; METABOLISM; PROCEDURES; TISSUE DISTRIBUTION;

ANIMALS; CELL LINE; CONTRAST MEDIA; DRUG STABILITY; FERRIC COMPOUNDS; FREEZE DRYING; LIVER; MAGNETIC RESONANCE IMAGING; MICE; NANOPARTICLES; PARTICLE SIZE; POWDERS; SUCCIMER; TISSUE DISTRIBUTION;

EID: 84914810814     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24209     Document Type: Article

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