Coxsackievirus B detection in cases of myocarditis, myopericarditis, pericarditis and dilated cardiomyopathy in hospitalized patients

Molecular Medicine Reports

Volumn 10, Issue 6, 2014, Pages 2811-2818

  Gaaloul, Imed ^a,b   Riabi, Samira ^a   Harrath, Rafik ^a   Hunter, Timothy ^b   Hamda, Khaldoun B ^c   Ghzala, Assia B ^d   Huber, Sally ^b   Aouni, Mahjoub ^a  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b UNIVERSITY OF VERMONT   (United States)

^c FATTOUMA BOURGUIBA UNIVERSITY HOSPITAL   (Tunisia)

^d University Hospitals Farhat Hached and Sahloul   (Tunisia)

Author keywords

Coxsackievirus B; Epidemiology; Human heart infections; Immunohistochemical investigations; Molecular diagnosis

Indexed keywords

ENTEROVIRUS; HUMAN ENTEROVIRUS B; MIRIDAE;

CAPSID PROTEIN;

ADOLESCENT; ADULT; BIOPSY; CARDIAC MUSCLE; CASE CONTROL STUDY; CONGESTIVE CARDIOMYOPATHY; ENTEROVIRUS B; ENTEROVIRUS INFECTIONS; FEMALE; GENETICS; HEART; HUMAN; MALE; MIDDLE AGED; MYOCARDITIS; PATHOLOGY; PERICARDITIS; VIROLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; BIOPSY; CAPSID PROTEINS; CARDIOMYOPATHY, DILATED; CASE-CONTROL STUDIES; ENTEROVIRUS B, HUMAN; ENTEROVIRUS INFECTIONS; FEMALE; HEART; HUMANS; MALE; MIDDLE AGED; MYOCARDITIS; MYOCARDIUM; PERICARDITIS; YOUNG ADULT;

EID: 84914170918     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2578     Document Type: Article

References (52)

1. Ben-Haim S, Gacinovic S and Israel O: Cardiovascular infection and inflammation. Semin Nucl Med 39: 103-114, 2009.
2. Mattingly TW: Changing concepts of myocardial diseases. JAMA 191: 33-37, 1965.
3. Kaski JP and Burch M: Viral myocarditis in childhood. Paediatr Child Health 17: 11-17, 2007.
4. Dörner A, Pauschinger M, Schwimmbeck PL, Kühl U and Schultheiss HP: The shift in the myocardial adenine nucleotide translocator isoform expression pattern is associated with an enteroviral infection in the absence of an active T-cell dependent immune response in human inflammatory heart disease. J Am Coll Cardiol 35: 1778-1784, 2000.
5. Zhang H, Li Y, Peng T, et al: Localization of enteroviral antigen in myocardium and other tissues from patients with heart muscle disease by an improved immunohistochemical technique. J Histochem Cytochem 48: 579-584, 2000.
6. Peng T, Li Y, Yang Y, et al: Characterization of enterovirus isolates from patients with heart muscle disease in a selenium-deficient area of China. J Clin Microbiol 38: 3538-3543, 2000.
7. Bowles NE, Olsen EGJ, Richardson PJ and Archarda LC: Detection of Coxsackie-B-virus-specific RNA sequences in myocardial biopsy samples from patients with myocarditis and dilated cardiomyopathy. Lancet 1: 1120-1123, 1986.
8. Pauschinger M, Phan MD, Doerner A, Kuehl U, et al: Enteroviral RNA replication in the myocardium of patients with left ventricular dysfunction and clinically suspected myocarditis. Circulation 99: 889-895, 1999.
9. Andreoletti L, Hober D, Decoene C, et al: Detection of enterovirus RNA by polymerase chain reaction in endomyocardial tissue of patients with chronic diseases. J Med Virol 48: 53-59, 1996.
10. Maekawa Y, Ouzounian M, Opavsky MA and Liu PP: Connecting the missing link between dilated cardiomyopathy and viral myocarditis: Virus, cytoskeleton, and innate immunity. Circulation 115: 5-8, 2007.
11. Petitjean J, Freymuth F, Kopecka H, et al: Entérovirus et cardiomyopathies. Méd Mal Infect 24: 102-107, 1994 (In French).
12. Kaski JP and Burch M: Viral myocarditis in Childhood. Pediatr Child Health 17: 11-18, 2007.
13. Dan M and Chantler JK: A genetically engineered attenuated coxsackievirus B3 strain protects mice against lethal infection. J Virol 79: 9285-9295, 2005.
14. Mariani M, Petronio AS, Manes MT, et al: Detection of enteroviral infection in myocardial tissues by polymerase chain reaction (PCR). Clin Microbiol Infect 2: 109-114, 1996.
15. Kandolf R, Klingel K, Zell R, et al: Molecular mechanisms in the pathogenesis of enteroviral heart disease: Acute and persistent infections. Clin Immunol Immunopathol 68: 153-158, 1993.
16. Muir P: The association of enteroviruses with chronic heart disease. Med Virol 2: 9-18, 1992.
17. Li Y, Bourlet T, Andreoletti L, et al: Enteroviral capsid protein VP1 is present in myocardial tissues from some patients with myocarditis or dilated cardiomyopathy. Circulation 101: 231-234, 2000.
18. Pauschinger M, Chandrasekharan K, Noutsias M, et al: Viral heart disease: Molecular diagnosis, clinical prognosis, and treatment strategies. Med Microbiol Immunol 193: 65-69, 2004.
19. D'Ambrosio A, Patti G, Manzoli A, et al: The fate of acute myocarditis between spontaneous improvement and evolution to dilated cardiomyopathy: A review. Heart 85: 499-504, 2001.
20. Goyle KK and Walling AD: Diagnosing pericarditis. Am Fam Physician 66: 1695-1702, 2002.
21. Ferreira Júnior AG, Ferreira SM, Gomes ML and Linhares AC: Enteroviruses as a possible cause of myocarditis, pericarditis and dilated cardiomyopathy in Belém, Brazil. Braz J Med Biol Res 28: 869-874, 1995.
22. Imazio M and Trinchero R: Myopericarditis: Etiology, management, and prognosis. Int J Cardiol 127: 17-26, 2008.
23. Smith WG: Coxsackie B myopericarditis in adults. Am Heart J 80: 34-46, 1970.
24. Imazio M and Trinchero R: The spectrum of inflammatory myopericardial diseases. Int J Cardiol 144: 124-134, 2010.
25. Imazio M, Cecchi E, Demichelis B, et al: Myopericarditis versus viral or idiopathic acute pericarditis. Heart 94: 498-501, 2008.
26. Leonard EG: Viral myocarditis. Pediatr Infect Dis J 23: 665-666, 2004.
27. Feldman AM and McNamara D: Myocarditis. N Engl J Med 343: 1388-1398, 2000.
28. Kandolf R, Ameis D, Kirschner P and Canu A: In situ detection of enteroviral genomes in myocardial cells by nucleic acid hybridization: An approach to the diagnosis of viral heart disease. Proc Natl Acad Sci USA 84: 6272-6276, 1987.
29. Klingel K, Rieger P, Mall G, et al: Visualization of enteroviral replication in myocardial tissue by ultrastructural in situ hybridization: Identification of target cells and cytopathic effects. Lab Invest 78: 1227-1237, 1998.
30. Rueckert RR: Picornaviridae: The viruses and their replication. In: Fields Virology. Fields BM, Knipe DM, Howley PM (eds). 3rd edition. Lippincott-Raven Publishers, Philadelphia, pp609-654, 1996.
31. Dettmeyer R, Baasner A, Schlamann M, Haag C and Madea B: Coxsackie B3 myocarditis in 4 cases of suspected sudden infant death syndrome: Diagnosis by immunohistochemical and molecular-pathologic investigations. Pathol Res Pract 198: 689-696, 2002.
32. Esfandiarei M, Suarez A, Amaral A, et al: Novel role for integrin-linked kinase in modulation of coxsackievirus B3 replication and virus-induced cardiomyocyte injury. Circ Res 99: 354-361, 2006.
33. Ahn J, Joo CH, Seo I, et al: All CVB, serotypes and clinical isolates induce irreversible cytopathic effects in primary cardiomyocytes. J Med Virol 75: 290-294, 2005.
34. Treacy A, Carr MJ, Dunford L, et al: First report of sudden death due to myocarditis caused by adenovirus serotype. J Clin Microbiol 48: 642-645, 2010.
35. Zhang H, Soteriou B, Knowlson S, Theodoridou A and Archard LC: Characterisation of genomic RNA of Coxsackievirus B3 in murine myocarditis: Reliability of direct sequencing of reverse transcription-nested polymerase chain reaction products. J Virol Methods 69: 7-17, 1997.
36. Zoll GJ, Melchers WJ, Kopecka H, et al: General primer-mediated polymerase chain reaction for detection of enteroviruses: Application for diagnostic routine and persistent infections. J Clin Microbiol 30: 160-165, 1992.
37. Altschul SF, Gish W, Miller W, Myers EW and Lipman DJ: Basic local alignment search tool. J Mol Biol 215: 403-410, 1990.
38. Oberste MS, Maher K, Flemister MR, et al: Comparison of classic and molecular approaches for the identification of untypeable enteroviruses. J Clin Microbiol 38: 1170-1174, 2000.
39. Cioc AM and Nuovo GJ: Histologic and in situ viral findings in the myocardium in cases of sudden, unexpected death. Mod Pathol 15: 914-922, 2001.
40. Dettmeyer R, Kandolf R, Schmidt P, Schlamann M and Madea B: Lympho monocytic enteroviral myocarditis traditional, immunohistological and molecularpathological methods for diagnosis in a case of suspected sudden infant death syndrome (SIDS). Forensic Sci Int 119: 141-144, 2001.
41. Guarner J, Bhatnagar J, Shieh WJ, et al: Histopathologic, immunohistochemical, and polymerase chain reaction assays in the study of cases with fatal sporadic myocarditis. Hum Pathol 38: 1412-1419, 2007.
42. Chimenti C and Frustaci A: Histopathology of myocarditis. Diagn Histopathol 14: 401-407, 2008.
43. Shi SR, Key ME and Kalra KL: Antigen retrieval in formalinfixed paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 39: 741-748, 1991.
44. Shi SR, Cote RJ and Taylor CR: Antigen retrieval immunohistochemistry: Past, present and future. J Histochem Cytochem 45: 327-343, 1997.
45. Sabattini E, Bisgard K, Ascani SS, Poggi, et al: The EnVision++ system: A new immunohistochemical method for diagnostics and research: Critical comparison with the APAAP, ChemMate, CSA, LABC and SABC techniques. J Clin Pathol 51: 506-511, 1998.
46. Jin O, Sole MJ, Butany JW, et al: Detection of enterovirus RNA in myocardial biopsies from patients with myocarditis and cardiomyopathy using gene amplification by polymerase chain reaction. Circulation 82: 8-16, 1990.
47. Guarner J, Bhatnagar J, Shieh WJ, et al: Histopathologic, immunohistochemical, and polymerase chain reaction assays in the study of cases with fatal sporadic myocarditis. Hum Pathol 38: 1412-1419, 2007.
48. Bowles NE, Ni J, Kearney DL, et al: Detection of viruses in myocardial tissues by polymerase chain reaction. Evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol 42: 466-472, 2003.
49. Cambridge M, MacArthur C, Waterson A, Goodwin J and Oakley C: Antibodies to Coxsackie B viruses in congestive cardiomyopathy. Br Heart J 41: 692-696, 1979.
50. Abzug MJ and Rotbart HA: Enterovirus infections of neonates and infants. Semin Pediatr Infect Dis 10: 169-176, 1999.
51. Peters NS and Poole-Wilson PA: Myocarditis - continuing clinical and pathologic confusion. Am Heart J 121: 942-946, 1991.
52. Bahri O, Rezig D, Ben Nejma-Oueslati B, et al: Enteroviruses in Tunisia: Virological surveillance over 12 years (1992-2003). J Med Microbiol 54: 63-69, 2005.