Coupled synthesis and translocation restrains polyphosphate to acidocalcisome-like vacuoles and prevents its toxicity

Journal of Cell Science

Volumn 127, Issue 23, 2014, Pages 5093-5104

  Gerasimaite, Ruta ^a   Sharma, Shruti ^a,b   Desfougères, Yann ^a   Schmidt, Andrea ^a   Mayer, Andreas ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b BOSE INSTITUTE   (India)

Author keywords

Acidocalcisome; Inorganic polyphosphate; VTC complex; Yeast vacuole

Indexed keywords

CHAPERONE; POLYPHOSPHATE; UNCLASSIFIED DRUG; VACUOLAR TRANSPORTER CHAPERONE; ACID ANHYDRIDE HYDROLASE; EXOPOLYPHOSPHATASE; SACCHAROMYCES CEREVISIAE PROTEIN; VESICULAR TRANSPORT PROTEIN; VTC1 PROTEIN, S CEREVISIAE;

ACIDOCALCISOME; ARTICLE; CELL ORGANELLE; CELL VACUOLE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ELECTROCHEMISTRY; ENZYME ACTIVE SITE; ENZYME SYNTHESIS; EUKARYOTE; NONHUMAN; TONOPLAST; ENZYMOLOGY; GENETICS; MEMBRANE POTENTIAL; METABOLISM; MUTATION; PH; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE; TIME; TRANSPORT AT THE CELLULAR LEVEL;

ACID ANHYDRIDE HYDROLASES; BIOLOGICAL TRANSPORT; CATALYTIC DOMAIN; CYTOSOL; HYDROGEN-ION CONCENTRATION; MEMBRANE POTENTIALS; MOLECULAR CHAPERONES; MUTATION; POLYPHOSPHATES; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TIME FACTORS; VACUOLES; VESICULAR TRANSPORT PROTEINS;

EID: 84914165781     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.159772     Document Type: Article

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