Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts

Journal of Molecular Medicine

Volumn 92, Issue 12, 2014, Pages 1271-1281

  Ota, Daichi ^a   Kanayama, Masashi ^a   Matsui, Yutaka ^a   Ito, Koyu ^a   Maeda, Naoyoshi ^a   Kutomi, Goro ^b   Hirata, Koichi ^b   Torigoe, Toshihiko ^c   Sato, Noriyuki ^c   Takaoka, Akinori ^a   Chambers, Ann F ^d   Morimoto, Junko ^e   Uede, Toshimitsu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b SAPPORO MEDICAL UNIVERSITY HOSPITAL   (Japan)

^c SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

^e UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Breast cancer; Cancer associated fibroblasts; Osteopontin; Tumor microenvironment; 9 1 integrin

Indexed keywords

ALPHA INTEGRIN; ALPHA9BETA1 INTEGRIN; INTEGRIN; OSTEOPONTIN; UNCLASSIFIED DRUG; INTEGRIN ALPHA 9 BETA 1;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INOCULATION; LYMPH NODE METASTASIS; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR VOLUME; WILD TYPE; ANIMAL; BREAST TUMOR; CELL PROLIFERATION; FEMALE; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; FIBROBLASTS; HUMANS; INTEGRINS; LYMPHATIC METASTASIS; MICE; MICE, KNOCKOUT; NEOPLASM INVASIVENESS; OSTEOPONTIN; SIGNAL TRANSDUCTION;

EID: 84914146487     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-014-1183-9     Document Type: Article

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