Expression of the Annexin A1 gene is associated with suppression of growth, invasion and metastasis of nasopharyngeal carcinoma

Molecular Medicine Reports

Volumn 10, Issue 6, 2014, Pages 3059-3067

  Liu, Aifeng ^a,b   Huang, Weiguo ^a   Zeng, Guqing ^a   Ma, Xiaohua ^b   Zhou, Xiao ^c   Wang, Yafei ^a   Ouyang, Chenjie ^a   Cheng, Ailan ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b CHANGSHA CENTRAL HOSPITAL   (China)

^c East Hospital District of Yueyang First People's Hospital   (China)

Author keywords

Annexin A1; Invasion; Metastasis; Nasopharyngeal carcinoma

Indexed keywords

LIPOCORTIN 1; SMALL INTERFERING RNA; TUMOR MARKER;

CELL MOTION; CELL PROLIFERATION; DISEASE COURSE; DOWN REGULATION; GENETICS; HUMAN; NASOPHARYNX TUMOR; PATHOLOGY; PROGNOSIS; TUMOR CELL LINE; UPREGULATION;

ANNEXIN A1; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE PROGRESSION; DOWN-REGULATION; HUMANS; NASOPHARYNGEAL NEOPLASMS; PROGNOSIS; RNA, SMALL INTERFERING; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84914102573     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2656     Document Type: Article

References (28)

1. Huang TR, Zhang SW, Chen WQ, et al: Trends in nasopharyngeal carcinoma mortality in China, 1973-2005. Asian Pac J Cancer Prev 13: 2495-2502, 2012.
2. Chan AT: Nasopharyngeal carcinoma. Ann Oncol 21 (Suppl 7): Vii308-vii312, 2010.
3. Yu MC and Yuan JM: Epidemiology of nasopharyngeal carcinoma. Semin Cancer Biol 12: 421-429, 2002.
4. Ren JS, Chen WQ, Shin HR, et al: A comparison of two methods to estimate the cancer incidence and mortality burden in China in 2005. Asian Pac J Cancer Prev 11: 1587-1594, 2010.
5. Chang ET and Adami HO: The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 15: 1765-1777, 2006.
6. King AD, Ahuja AT, Leung SF, et al: Neck node metastases from nasopharyngeal carcinoma: MR imaging of patterns of disease. Head Neck 22: 275-281, 2000.
7. Huang CJ, Leung SW, Lian SL, Wang CJ, Fang FM and Ho YH: Patterns of distant metastases in nasopharyngeal carcinoma. Kaohsiung J Med Sci 12: 229-234, 1996.
8. Lim LH and Pervaiz S: Annexin 1: The new face of an old molecule. FASEB J 21: 968-975, 2007.
9. Patel DM, Ahmad SF, Weiss DG, Gerke V and Kuznetsov SA: Annexin A1 is a new functional linker between actin filaments and phagosomes during phagocytosis. J Cell Sci 124: 578-588, 2011.
10. Garcia Pedrero JM, Fernandez MP, Morgan RO, et al: Annexin A1 down-regulation in head and neck cancer is associated with epithelial differentiation status. Am J Pathol 164: 73-79, 2004.
11. Zhang L, Yang X, Zhong LP, et al: Decreased expression of Annexin A1 correlates with pathologic differentiation grade in oral squamous cell carcinoma. J Oral Pathol Med 38: 362-370, 2009.
12. Wang LD, Yang YH, Liu Y, Song HT, Zhang LY and Li PL: Decreased expression of annexin A1 during the progression of cervical neoplasia. J Int Med Res 36: 665-672, 2008.
13. Chiu CC, Lin CY, Lee LY, et al: Molecular chaperones as a common set of proteins that regulate the invasion phenotype of head and neck cancer. Clin Cancer Res 17: 4629-4641, 2011.
14. Cheng AL, Huang WG, Chen ZC, et al: Identificating cathepsin D as a biomarker for differentiation and prognosis of nasopharyngeal carcinoma by laser capture microdissection and proteomic analysis. J Proteome Res 7: 2415-2426, 2008.
15. Gerke V and Moss SE: Annexins: From structure to function. Physiol Rev 82: 331-371, 2002.
16. McArthur S, Cristante E, Paterno M, et al: Annexin A1: A central player in the anti-inflammatory and neuroprotective role of microglia. J Immunol 185: 6317-6328, 2010.
17. Lecona E, Barrasa JI, Olmo N, Llorente B, Turnay J and Lizarbe MA: Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: Role of p53, NF-Y, and p38 mitogen-activated protein kinase. Mol Cell Biol 28: 4665-4674, 2008.
18. Sakaguchi M, Murata H, Sonegawa H, et al: Truncation of annexin A1 is a regulatory lever for linking epidermal growth factor signaling with cytosolic phospholipase A2 in normal and malignant squamous epithelial cells. J Biol Chem 282: 35679-35686, 2007.
19. Alldridge LC and Bryant CE: Annexin 1 regulates cell proliferation by disruption of cell morphology and inhibition of cyclin D1 expression through sustained activation of the ERK1/2 MAPK signal. Exp Cell Res 290: 93-107, 2003.
20. Parente L and Solito E: Annexin 1: More than an anti-phospholipase protein. Inflamm Res 53: 125-132, 2004.
21. Hsiang CH, Tunoda T, Whang YE, Tyson DR and Ornstein DK: The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells. Prostate 66: 1413-1424, 2006.
22. Yang XY, Ren CP, Wang L, et al: Identification of differentially expressed genes in metastatic and non-metastatic nasopharyngeal carcinoma cells by suppression subtractive hybridization. Cell Oncol 27: 215-223, 2005.
23. Paweletz CP, Ornstein DK, Roth MJ, et al: Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma. Cancer Res 60: 6293-6297, 2000.
24. Deng S, Wang J, Hou L, et al: Annexin A1, A2, A4 and A5 play important roles in breast cancer, pancreatic cancer and laryngeal carcinoma, alone and/or synergistically. Oncol Lett 5: 107-112, 2013.
25. Yom CK, Han W, Kim SW, et al: Clinical significance of annexin A1 expression in breast cancer. J Breast Cancer 14: 262-268, 2011.
26. Wang LP, Bi J, Yao C, et al: Annexin A1 expression and its prognostic significance in human breast cancer. Neoplasma 57: 253-259, 2010.
27. Babbin BA, Lee WY, Parkos CA, et al: Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors. J Biol Chem 281: 19588-19599, 2006.
28. Cheng TY, Wu MS, Lin JT, et al: Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway. Cancer 118: 5757-5767, 2012.