GNAS mutation as an alternative mechanism of activation of the Wnt/β-catenin signaling pathway in gastric adenocarcinoma of the fundic gland type

Human Pathology

Volumn 45, Issue 12, 2014, Pages 2488-2496

  Nomura, Ryosuke ^a   Saito, Tsuyoshi ^a   Mitomi, Hiroyuki ^b   Hidaka, Yasuhiro ^a   Lee, Se Yong ^a   Watanabe, Sumio ^a   Yao, Takashi ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

APC; AXIN; CTNNB1; Gastric adenocarcinoma of the fundic gland type; GNAS; KRAS; Mutation

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; K RAS PROTEIN; WNT PROTEIN; GNAS PROTEIN, HUMAN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; EXON; FEMALE; GASTRIC ADENOCARCINOMA OF THE FUNDIC GLAND TYPE; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PROTEIN EXPRESSION; STOMACH ADENOCARCINOMA; TUMOR INVASION; TUMOR VOLUME; WNT SIGNALING PATHWAY; ADENOCARCINOMA; GENETICS; METABOLISM; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; STOMACH FUNDUS; STOMACH MUCOSA; STOMACH TUMOR; VERY ELDERLY;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BETA CATENIN; DNA MUTATIONAL ANALYSIS; FEMALE; GASTRIC FUNDUS; GASTRIC MUCOSA; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; STOMACH NEOPLASMS; WNT SIGNALING PATHWAY;

EID: 84913616338     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2014.08.016     Document Type: Article

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