The effects of sesquiterpenes-rich extract of Alpinia oxyphylla Miq. On amyloid- β -induced cognitive impairment and neuronal abnormalities in the cortex and hippocampus of mice

Oxidative Medicine and Cellular Longevity

Volumn 2014, Issue , 2014, Pages

  Shi, Shao Huai ^a   Zhao, Xu ^a   Liu, Bing ^a   Li, Huan ^a   Liu, Ai Jing ^a   Wu, Bo ^a   Bi, Kai Shun ^a   Jia, Ying ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; GLYCOPROTEINS; MAMMALS; OLEFINS;

ACETYLCHOLINESTERASE; ALPINIA OXYPHYLLA MIQ; COGNITIVE IMPAIRMENT; COGNITIVE PERFORMANCE; GLUTATHIONE PEROXIDASE; LEARNING AND MEMORY; NEUROPROTECTIVE ACTIVITY; POSSIBLE MECHANISMS;

NEURONS;

ACETYLCHOLINESTERASE; ALPINIA OXYPHYLLA EXTRACT; AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE; DONEPEZIL; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; NEUROPROTECTIVE AGENT; PLANT EXTRACT; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT; SECRETASE; SESQUITERPENE;

ACTIVE AVOIDANCE TEST; AGING; ALPINIA; ALPINIA OXYPHYLLA; AMNESIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN CORTEX; CELL ACTIVATION; CHEMICAL COMPOSITION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HIPPOCAMPUS; LEARNING DISORDER; LIPID PEROXIDATION; LOCOMOTION; LONG TERM CARE; MALE; MICROGLIA; MORRIS WATER MAZE TEST; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; REGULATORY MECHANISM; SHORT TERM MEMORY; Y-MAZE TEST; ANIMAL; ANIMAL BEHAVIOR; CHEMICALLY INDUCED; CHEMISTRY; COGNITION DISORDERS; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTITUTE FOR CANCER RESEARCH MOUSE; MAZE TEST; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ACETYLCHOLINESTERASE; ALPINIA; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COGNITION DISORDERS; GLUTATHIONE PEROXIDASE; HIPPOCAMPUS; MALE; MALONDIALDEHYDE; MAZE LEARNING; MICE; MICE, INBRED ICR; PEPTIDE FRAGMENTS; PLANT EXTRACTS; SESQUITERPENES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84913565588     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/451802     Document Type: Article

References (30)

1. M. Prince, "The global prevalence of dementia, " in World Alzheimer Report 2009, M. Prince and J. Jackson, Eds. , pp. 25-45, Alzheimers Disease International, 2009.
2. X. L. Li, D. S. Wang, B. Q. Zhao et al., "Effects ofChinese herbal medicine fuzhisan on aged rats, " Experimental Gerontology, vol. 43, no. 9, pp. 853-858, 2008.
3. W. J. Krall, J. J. Sramek, and N. R. Cutler, "Cholinesterase inhibitors: a therapeutic strategy for Alzheimer disease, " Annals of Pharmacotherapy, vol. 33, no. 4, pp. 441-450, 1999.
4. E. Giacobini, "Cholinesterase inhibitors: new roles and therapeutic alternatives, " Pharmacological Research, vol. 50, no. 4, pp. 433-440, 2004.
5. C. G. Ballard, N. H. Greig, A. L. Guillozet-Bongaarts, A. Enz, and S. Darvesh, "Cholinesterases: roles in the brain during health and disease, " Current Alzheimer Research, vol. 2, no. 3, pp. 307-318, 2005.
6. A. Bulbarelli, E. Lonati, E. Cazzaniga et al., "TrkA pathway activation induced by amyloid-beta (Abeta), " Molecular and Cellular Neuroscience, vol. 40, no. 3, pp. 365-373, 2009.
7. S. Lesné, T. K. Ming, L. Kotilinek et al., "A specific amyloid-β protein assembly in the brain impairs memory, " Nature, vol. 440, no. 7082, pp. 352-357, 2006.
8. K. A. Bates, G. Verdile, Q.-X. Li et al., "Clearance mechanisms of Alzheimers amyloid-B peptide: implications for therapeutic design and diagnostic tests, "Molecular Psychiatry, vol. 14, no. 5, pp. 469-486, 2009.
9. A. Itoh, A. Nitta, M. Nadai et al., "Dysfunction of cholinergic and dopaminergic neuronal systems in β-amyloid proteininfused rats, " Journal of Neurochemistry, vol. 66, no. 3, pp. 1113-1117, 1996.
10. J. G. Luo, X. Q. Lv, X. B. Wang, and L. Kong, "Sesquiterpenoids from the fruits of Alpinia oxyphylla and inhibition of nitric oxide production in lipopolysaccaride-activated macrophages," Phytochemistry Letters, vol. 5, no. 1, pp. 134-138, 2012.
11. O. Muraoka, M. Fujimoto, G. Tanabe et al., "Absolute stereostructures of novel norcadinane-and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla, " Bioorganic and Medicinal Chemistry Letters, vol. 11, no. 16, pp. 2217-2220, 2001.
12. T. Morikawa, H. Matsuda, I. Toguchida, K. Ueda, and M. Yoshikawa, "Absolute stereostructures of three new sesquiterpenes fromthe fruit of Alpinia oxyphylla with inhibitory effects on nitric oxide production and degranulation in RBL-2H3 cells, " Journal of Natural Products, vol. 65, no. 10, pp. 1468-1474, 2002.
13. J. Xu, N. Tan, G. Zeng et al., "Studies on chemical constituents in fruit of Alpinia oxyphylla, " China Journal of Chinese Materia Medica, vol. 34, no. 8, pp. 990-993, 2009.
14. G. F. Shi, L. J. An, B. Jiang, S. Guan, and Y. Bao, "Alpinia protocatechuic acid protects against oxidative damage in vitro and reduces oxidative stress in vivo, " Neuroscience Letters, vol. 403, no. 3, pp. 206-210, 2006.
15. X. Yu, L. An, Y. Wang, H. Zhao, and C. Gao, "Neuroprotective effect of Alpinia oxyphylla Miq. fruits against glutamateinduced apoptosis in cortical neurons, " Toxicology Letters, vol. 144, no. 2, pp. 205-212, 2003.
16. M. Sarter, G. Bodewitz, and D. N. Stephens, "Attenuation of scopolamine-induced impairment of spontaneous alternation behaviour by antagonist but not inverse agonist and agonist β-carbolines, " Psychopharmacology, vol. 94, no. 4, pp. 491-495, 1988.
17. L. A. León, J. Landeira-Fernandez, and F. P. Cardenas, "Effects of chronic intracerebroventricular 3, 4-methylenedioxy-Nmethamphetamine (MDMA) or fluoxetine on the active avoidance test in rats with or without exposure to mild chronic stress, " Behavioural Brain Research, vol. 205, no. 1, pp. 259-264, 2009.
18. J. Lu, Y. Zheng, D. Wu, L. Luo, D. Sun, and Q. Shan, "Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose," Biochemical Pharmacology, vol. 74, no. 7, pp. 1078-1090, 2007.
19. T. Ahmed and A. Gilani, "Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamineinduced amnesia may explain medicinal use of turmeric in Alzheimers disease, " Pharmacology Biochemistry and Behavior, vol. 91, no. 4, pp. 554-559, 2009.
20. S. Y. Kang, K. Y. Lee, Y. C. Kim, M. J. Park, G. J. Markelonis, and T. H. Oh, "Decursin fromAngelica gigas mitigates amnesia induced by scopolamine in mice, " Neurobiology of Learning and Memory, vol. 79, no. 1, pp. 11-18, 2003.
21. G. L. Ellman, K. D. Courtney, V. Andres Jr. , and R. M. Featherstone, "A new and rapid colorimetric determination of acetylcholinesterase activity, " Biochemical Pharmacology, vol. 7, no. 2, pp. 88-IN2, 1961.
22. B. T. Hyman, G. W. Van Hoesen, A. R. Damasio, and C. L. Barnes, "Alzheimers disease: cell-specific pathology isolates the hippocampal formation, " Science, vol. 225, no. 4667, pp. 1168-1170, 1984.
23. B. M. Fraga, M. G. Hernandez, T. Mestres, D. Terrero, and J. M. Arteaga, "Nor-sesquiterpenes from Teucrium heterophyllum," Phytochemistry, vol. 39, no. 3, pp. 617-619, 1995.
24. J. Xu, C. Ji, Y. Zhang, J. Su, Y. Li, and N. Tan, "Inhibitory activity of eudesmane sesquiterpenes from Alpinia oxyphylla on production of nitric oxide, " Bioorganic and Medicinal Chemistry Letters, vol. 22, no. 4, pp. 1660-1663, 2012.
25. K. K. Wong, C. C. Wan, and P. C. Shaw, "Ethanol extract of Alpinia oxyphylla fructus shows inhibition of tau protein phosphorylation in cell culture, " Neurobiology of Aging, vol. 25, no. 2, pp. 595-597, 2004.
26. S. W. Pimplikar, R. A. Nixon, N. K. Robakis, J. Shen, and L. Tsai, "Amyloid-independent mechanisms in Alzheimers disease pathogenesis, " Journal of Neuroscience, vol. 30, no. 45, pp. 14946-14954, 2010.
27. T. Lynch, R. A. Cherny, and A. I. Bush, "Oxidative processes in Alzheimer's disease: the role of Aβ-metal interactions," Experimental Gerontology, vol. 35, no. 4, pp. 445-451, 2000.
28. Z. Lan, J. Liu, L. Chen et al., "Danggui-Shaoyao-San ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in d-galactose-induced senescent mice, " Journal of Ethnopharmacology, vol. 141, no. 1, pp. 386-395, 2012.
29. P. Chen, P. Wang, G. Shao, and L. Xiang, "Acetylcholinesterase inhibitory activities of 48 traditional Chinese medicinal herbs," Journal of Chinese Pharmaceutical Sciences, vol. 22, no. 1, pp. 106-109, 2013.
30. J. A. Anderson and J. R. Coats, "Acetylcholinesterase inhibition by nootkatone and carvacrol in arthropods, " Pesticide Biochemistry and Physiology, vol. 102, no. 2, pp. 124-128, 2012.