Recommendations for the treatment of osteomyelitis

Brazilian Journal of Infectious Diseases

Volumn 18, Issue 5, 2014, Pages 526-534

  Lima, Ana Lucia L ^a   Oliveira, Priscila R ^a   Carvalho, Vladimir C ^a   Cimerman, Sergio ^b   Savio, Eduardo ^c   Sosa, Anibal ^d   López, Alejandro ^e   Rodriguez Taveras, Carlos Julio ^f   Ferreira Starling, Carlos Ernesto ^g   Kiffer, Carlos ^h   Dos Santos, Eliana Lima Bicudo ⁱ   Molinedo Pérez, Luis Elvin ^j   Coura Filho, George Barberio ^a   Del Sel, Hernan ^k   Pezzarossi Zelaya, Hugo Eduardo ^l   Marinho, Ivan ^m   Lopes Rocha, Jaime Luís ⁿ   Matheus Guimarães, João Antonio ^o   Mello Sampaio, Jorge Luiz ^a   Amim Zabeu, José Luiz ^p   Melo, Luiz Henrique ^q   Abagge, Marcelo ⁿ   Costa Salles, Mauro José ^r   Ferreira, Marcelo Simão ^s   De Rezende, Marcelo Rosa ^a   Rodrigues, Marcelo Bordalo ^a   Lech, Osvandré ^t   Dos Reis, Paulo Roberto ^a   Ramon Pardo, Pilar ^u   Guarniero, Roberto ^a   Junior, Walter Ricioli ^r   more..

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO DE INFECTOLOGIA EMÍLIO RIBAS   (Brazil)

^c UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^d International Independent Consultant Ser vices Infectious Diseases and Clinical Microbiology   (United States)

^e Sanatorio Allende   (Argentina)

^f Hospital Central de Las Fuerzas Armadas   (Dominican Republic)

^g HOSPITAL VERA CRUZ   (Brazil)

^h FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

ⁱ UNIVERSITY OF BRASILIA   (Brazil)

^j UNIVERSIDAD MAYOR DE SAN ANDRÉS   (Bolivia)

^k HOSPITAL BRITÁNICO DE BUENOS AIRES   (Argentina)

^l Infectocentro   (Guatemala)

^m Intensimed Research Group Intensive Care Unit Hospital São Camilo Pompéia   (Brazil)

ⁿ FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^o Instituto Nacional de Traumatologia e Ortopedia   (Brazil)

^p PONTIFÍCIA UNIVERSIDADE CATÓLICA DE CAMPINAS   (Brazil)

^q Univille   (Brazil)

^r FACULDADE DE CIÊNCIAS MÉDICAS DA SANTA CASA DE SÃO PAULO   (Brazil)

^s FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

^t Hospital Escola São Vicente de Paulo   (Brazil)

^u WORLD HEALTH ORGANIZATION   (Switzerland)

more..

Author keywords

Bone and joint infection; Infectious diseases; Osteomyelitis; Soft tissue infection

Indexed keywords

AMOXICILLIN; AMPICILLIN; AZITHROMYCIN; BONE CEMENT; C REACTIVE PROTEIN; CEFAZOLIN; CEFEPIME; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; CLAVULANIC ACID; CLINDAMYCIN; DAPTOMYCIN; ERTAPENEM; ERYTHROMYCIN; GALLIUM 67; INDIUM 111; INTERLEUKIN 6; LEVOFLOXACIN; LINEZOLID; OXACILLIN; PIPERACILLIN; PROCALCITONIN; RIFAMPICIN; SULBACTAM; TAZOBACTAM; TEICOPLANIN; TIGECYCLINE; VANCOMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; BONE SCINTISCANNING; COLOR ULTRASOUND FLOWMETRY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; DEBRIDEMENT; DISEASE CLASSIFICATION; DISEASE MARKER; HISTOLOGY; HUMAN; HYPERBARIC OXYGEN; LABORATORY DIAGNOSIS; MICROBIOLOGICAL EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOMYELITIS; PALLIATIVE THERAPY; PROPIONIBACTERIUM ACNES; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; SHORT SURVEY; SURGICAL DRAINAGE; TREATMENT DURATION; TREATMENT RESPONSE; ULTRASOUND; VACUUM ASSISTED CLOSURE; ACUTE DISEASE; CHRONIC DISEASE; MULTIMODALITY CANCER THERAPY; PRACTICE GUIDELINE;

ACUTE DISEASE; ANTI-BACTERIAL AGENTS; CHRONIC DISEASE; COMBINED MODALITY THERAPY; HUMANS; HYPERBARIC OXYGENATION; OSTEOMYELITIS;

EID: 84912576216     PISSN: 14138670     EISSN: 16784391     Source Type: Journal    
DOI: 10.1016/j.bjid.2013.12.005     Document Type: Short Survey

References (73)

1. Lima A.L.L.M., Lopez A., Sosa A., et al. Directrices Panamericanas para el tratamiento de las osteomielitis e infecciones de tejidos blandos. Rev Panam de Infectol 2013, 15(1 Suppl. 1):S4. Asociación Panamericana de Infectología. http://www.revista-api.com/.
2. Waldvogel F.A., Medoff G., Swartz M.N. Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects. N Engl J Med 1970, 282:198-206.
3. Cierny G., Mader J.T., Penninck J.J. A clinical stage system for adult osteomyelitis. Contemp Orthop 1985, 10:17-37.
4. Esterhai J.L., Rao N. The epidemiology of musculoskeletal infections. Orthopaedic knowledge update musculoskeletal infection 2009, American Academy of Orthopaedic Surgeons, Rosemont. G. Cierny, A.C. McLaren, M.D. Wongworawat (Eds.).
5. Lima A.L.L.M., Zumiotti A.V. Aspectos atuais do diagnóstico e tratamento das osteomielites. Acta Ortop Bras 1999, 7:135-142.
6. Norden C, Gillespie WJ, Nade S. Clinical syndromes. In: Norden C, editor. Infections in bone and joints, vol. 3; 1994. USA, Pennsylvania, Blackwell. p. 137-387.
7. Trueta J. The three types of acute haematogenous osteomyelitis: a clinical and vascular study. J Bone Joint Surg 1959, 41:671-680.
8. Cierny G., Mader J.T. Adult chronic osteomyelitis. Orthopedics 1984, 7:1557-1564.
9. Wiesseman G.J., Wood V.E., Kroll L.L., Linda L. Pseudomonas vertebral osteomyelitis in heroin addicts. Report of five cases. J Bone Joint Surg Am 1973, 55:1416-1424.
10. Cierny G., Mader J.T. Adult chronic osteomyelitis. An review. Orthopaedic infections 1989, 31-48. Slack, Thorofare, NJ. R.D. D'Ambrosia, R.L. Marier (Eds.).
11. Berbari EF, Steckelberg JM, Osmon DR. Osteomyelitis. Principles and practice of infectious diseases, vol. 2. Philadelphia, Churchill Livingstone; 2005. p. 1322.
12. Romanò C.L., Romanò D., Logoluso N., Drago L. Bone and joint infections in adults: a comprehensive classification proposal. Eur Orthop Traumatol 2011, 1:207-217.
13. Calhoun J.H., Manring M.M. Adult osteomyelitis. Infect Dis Clin North Am 2005, 19:765-786.
14. Lew D.P., Waldvogel F.A. Osteomyelitis. Lancet 2004, 364:369-379.
15. Unkila-Kallio L., Kallio M.J., Eskola J., Peltola H. Serum C-reactive protein, erythrocyte sedimentation rate, and white blood cell count in acute hematogenous osteomyelitis of children. Pediatrics 1994, 93:59-62.
16. Roine I., Faingezicht I., Arguedas A., Herrera J.F., Rodríguez F. Serial serum C-reactive protein to monitor recovery from acute hematogenous osteomyelitis in children. Pediatr Infect Dis J 1995, 14:40-44.
17. Mutluoğlu M., Uzun G., Ipcioğlu O.M., et al. Can procalcitonin predict bone infection in people with diabetes with infected foot ulcers? A pilot study. Diabetes Res Clin Pract 2011, 94:53-56.
18. Faesch S., Cojocaru B., Hennequin C., et al. Can procalcitonin measurement help the diagnosis of osteomyelitis and septic arthritis? A prospective trial. Ital J Pediatr 2009, 35:33.
19. Butbul-Aviel Y., Koren A., Halevy R., Sakran W. Procalcitonin as a diagnostic aid in osteomyelitis and septic arthritis. Pediatr Emerg Care 2005, 21:828-832.
20. Berbari E., Mabry T., Tsaras G., et al. Inflammatory blood laboratory levels as markers of prosthetic joint infection: a systematic review and meta-analysis. J Bone Joint Surg Am 2010, 92:2102-2109.
21. Ochsner P.E., Hailemariam S. Histology of osteosynthesis associated bone infection. Int J Care Injury 2006, 37(Suppl. 2):S49-S58.
22. Zuluaga A.F., Galvis W., Saldarriaga J.G., Agudelo M., Salazar B.E., Vesga O. Etiologic diagnosis of chronic osteomyelitis: a prospective study. Arch Intern Med 2006, 166:95-100.
23. Wu J.S., Gorbachova T., Morrison W.B., Haims A.H. Imaging guided bone biopsy for osteomyelitis: are there factors associated with positive or negative cultures. AJR Am J Roentgenol 2007, 188:1529-1534.
24. Tohtz S.W., Müller M., Morawietz L., Winkler T., Perka C. Validity of frozen sections for analysis of periprosthetic loosening membranes. Clin Orthop Relat Res 2010, 468:762-768.
25. Schäfer P., Fink B., Sandow D., Margull A., Berger I., Frommelt L. Prolonged bacterial culture to identify late periprosthetic joint infection: a promising strategy. Clin Infect Dis 2008, 47:1403-1409.
26. Cataldo M.A., Petrosillo N., Cipriani M., Cauda R., Tacconelli E. Prosthetic joint infection: recent developments in diagnosis and management. J Infect 2010, 61:443-448.
27. Pitt W.G., Ross S.A. Ultrasound increases the rate of bacterial cell growth. Biotechnol Prog 2003, 19:1038-1044.
28. Termaat M.F., Raijmakers P.G., Scholten H.J., Bakker F.C., Patka P., Haarman H.J. The accuracy of diagnostic imaging for the assessment of chronic osteomyelitis: a systematic review and meta-analysis. J Bone Joint Surg Am 2005, 87:2464-2471.
29. Dormans J.P., Drummond D.S. Pediatric hematogenous osteomyelitis: new trends in presentation, diagnosis and treatment. J Am Acad Orthop Surg 1994, 2:333-341.
30. Hatzenbuehler J., Pulling T.J. Diagnosis and management of osteomyelitis. Am Fam Physician 2011, 84:1027-1033.
31. Kapoor A., Page S., Lavalley M., Gale D.R., Felson D.T. Magnetic resonance imaging for diagnosing foot osteomyelitis: a meta-analysis. Arch Intern Med 2007, 167:125-132.
32. Pineda C., Vargas A., Rodríguez A.V. Imaging of osteomyelitis: current concepts. Infect Dis Clin North Am 2006, 20:789-825.
33. Saigal G., Azouz E.M., Abdenour G. Imaging of osteomyelitis with special reference to children. Semin Musculoskelet Radiol 2004, 8:255-265.
34. Tehranzadeh J., Wong E., Wang F., Sadighpour M. Imaging of osteomyelitis in the mature skeleton. Radiol Clin North Am 2001, 39:223-250.
35. Dinh M.T., Abad C.L., Safdar N. Diagnostic accuracy of the physical examination and imaging tests for osteomyelitis underlying diabetic foot ulcers: meta-analysis. Clin Infect Dis 2008, 47:519-527.
36. Strobel K., Stumpe D. PET/CT in musculoskeletal infection. Semin Musculoskelet Radiol 2007, 11:353-364.
37. Abdullah Z.S., Khan M.U., Kodali S.K., Javaid A. Pyomiositis mimicking osteomyelitis detected by SPECT/CT. Hell J Nucl Med 2010, 13:277-279.
38. Chen W.C., Tsai K.D., Chen C.H., et al. Role of gallium 67 scintigraphy in the evaluation of occult sepsis in the medical ICU. Intern Emerg Med 2012, 7:53-58.
39. Sandler M.P., Coleman R.E., Patton J.A., Wackers F.J.T., Gottschalk A. Diagnostic nuclear medicine 2003, Lippincott Williams & Wilkins, Philadelphia. 4th ed.
40. Landersdorfer C.B., Bulitta J.B., Kinzig M., Holzgrabe U., Sörgel F. Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations. Clin Pharmacokinet 2009, 48:89-124.
41. Stengel D., Bauwens K., Sehouli J., Ekkernkamp A., Porzsolt F. Systematic review and meta-analysis of antibiotic therapy for bone and joint infections. Lancet Infect Dis 2001, 1:175-188.
42. Traunmüller F., Schintler M.V., Metzler J., et al. Soft tissue and bone penetration abilities of daptomycin in diabetic patients with bacterial foot infections. J Antimicrob Chemother 2010, 65:1252-1257.
43. Trampuz A., Zimmerli W. Diagnosis and treatment of infections associated with fracture-fixation devices. Injury 2006, 37:S59-S66.
44. Trampuz A., Widmer A.F. Infections associated with orthopedic implants. Curr Opin Infect Dis 2006, 19:349-356.
45. Miclau T., Schmidt A.H., Wenke J.C., et al. Infection. Orthop Trauma 2010, 24:583-586.
46. Frommelt L. Principles of systemic antimicrobial therapy in foreign material associated infection in bone tissue, with special focus on periprosthetic infection. Injury 2006, 37:S87-S94.
47. Lima A.L.L.M., Oliveira P.R.D. Uso de antimicrobianos em pacientes ortopédicos. Melhorando o uso de antimicrobianos em hospitais 2007, Associação Paulista de Estudos e Controle de Infecção Hospitalar, São Paulo.
48. Zimmerli W., Widmer A.F., Blatter M., Frei R., Ochsner P.E. Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. JAMA 1998, 279:1537-1541. Foreign-Body Infection (FBI) Study Group.
49. Baumbach S.F., Hobohm L., Wozasek G.E. A treatment strategy for complex cases of osteomyelitis in children and its applicability on three exemplary cases. J Pediatr Orthop B 2011, 20:432-435.
50. Lazzarini L., Mader J.T., Calhoun J.H. Osteomyelitis in long bonés. J Bone Joint Surg Am 2004, 86-A:2305-2318.
51. Rao N., Ziran B.H., Lipsky B.A. Treating osteomyelitis: antibiotics and surgery. Plast Reconstr Surg 2011, 127(Suppl. 1):177S-187S.
52. Copley L.A.B. Pediatric musculoskeletal infections. Orthopaedic knowledge update pediatrics 2011, American Academy of Orthopaedic Surgeons, Rosemont. K.M. Song (Ed.).
53. Dimeglio A. Ortopedia pediátrica 1990, São Paulo, Santos.
54. Dormans J., Drummond D.S. Pediatric hematogenous osteomyelitis: new trends in presentation, diagnosis, and treatment. J Am Acad Orthop Surg 1994, 2:333-341.
55. Trebse R., Milosev I., Kovac S., Mikek M., Pisot V. Poor results from the isoelastic total hip replacement: 14-17-year follow-up of 149 cementless prostheses. Acta Orthop 2005, 76:169-176.
56. Simpson A.H., Deakin M., Latham J.M. Chronic osteomyelitis: the effect of the extent of surgical resection on infection-free survival. J Bone Joint Surg Br 2001, 83:403-407.
57. Tetsworth K., Cierny G. Osteomyelitis debridement techniques. Clin Orthop Relat Res 1999, 87-96.
58. Svoboda S.J., Bice T.G., Gooden M.A., Brooks D.E., Thomas D.B., Wenke J.C. Comparison of bulb syringe and pulsed lavage irrigation with use of a bioluminescent musculoskeletal wound model. J Bone Joint Surg 2006, 88:2167-2174.
59. Springer B.D., Lee G.C., Osmon D., Haidukewych G.J., Hanssen A.D., Jacofsky D.J. Sisteic safety of high-dose antibiotic-loaded cement spacers after resection of an infected total knee arthroplasty. Clin Orthop Relat Res 2004, 47-51.
60. Zalavras C.G., Patzakis M.J., Holtom P. Local antibiotic therapy in the treatment of open fractures and osteomyelitis. Clin Orthop Relat Res 2004, 86-93.
61. Hungria Filho J.S. Infecções osteoarticulares: tratamento racional baseado na patologia: Sarvier 1992.
62. Forsberg J.A., Potter B.K., Cierny G, Webb L. Diagnosis and management of chronic infection. J Am Acad Orthop Surg 2011, 19(Suppl. 1):S8-S19.
63. Schmidt H.G., Tiemann A.H., Braunschweig R., et al. Arbeitsgemeinschaft septische Chirugie der DGOUC10. Z Orthop Unfall 2011, 149:449-460.
64. Darouiche R.O. Treatment of infections associated with surgical implants. N Engl J Med 2004, 350:1422-1429.
65. Conterno L.O., da Silva Filho C.R. Antibiotics for treating chronic osteomyelitis in adults. Cochrane Database Syst Rev 2009, CD004439.
66. Berendt A.R., Peters E.J., Bakker K., et al. Diabetic foot osteomyelitis: a progress report on diagnosis and a systematic review of treatment. Diabetes Metab Res Rev 2008, 24(Suppl. 1):S145-S161.
67. Gosselin R.A., Roberts I., Gillespie W.J. Antibiotics for preventing infection in open limb fractures. Cochrane Database Syst Rev 2004, CD003764.
68. Walter G., Kemmerer M., Kappler C., Hoffmann R. Treatment algorithms for chronic osteomyelitis. Dtsch Arztebl Int 2012, 109:257-264.
69. Parsons B., Strauss E. Surgical management of chronic osteomyelitis. Am J Surg 2004, 188(1A Suppl.):57-66.
70. Petersen K., Riddle M.S., Danko J.R., et al. Trauma-related infections in battlefield casualties from Iraq. Ann Surg 2007, 245:803-811.
71. Marx R.E., Ehler W.J., Tayapongsak P., Pierce L.W. Relationship of oxygen dose to angiogenesis induction in irradiated tissue. Am J Surg 1990, 160:519-524.
72. Calzia E., Oter S., Muth C.M., Radermacher P. Evolving career of hyperbaric oxygen in sepsis: from augmentation of oxygen delivery to the modulation of the immune response. Crit Care Med 2006, 34:2693-2695.
73. Buras J. Basic mechanisms of hyperbaric oxygen in the treatment of ischemia-reperfusion injury. HBO symposium 1999.