Photodegradation of the antineoplastic cyclophosphamide: A comparative study of the efficiencies of UV/H2O2, UV/Fe2+/H2O2 and UV/TiO2 processes

Chemosphere

Volumn 120, Issue , 2015, Pages 538-546

  Lutterbeck, Carlos Alexandre ^a,b   Machado, Ênio Leandro ^b   Kümmerer, Klaus ^a  

^a LEUPHANA UNIVERSITY OF LÜNEBURG   (Germany)

^b UNIVERSITY OF SANTA CRUZ DO SUL   (Brazil)

Author keywords

Advanced oxidation; Cyclophosphamide; Degradation; Ecotoxicity; Mineralization; Transformation products

Indexed keywords

DEGRADATION; LIGHT SOURCES; MINERALOGY; ORGANIC CARBON; WASTEWATER TREATMENT; WATER TREATMENT;

ADVANCED OXIDATION; CYCLOPHOSPHAMIDE; ECOTOXICITY; MINERALIZATION; TRANSFORMATION PRODUCTS;

IRON COMPOUNDS;

CYCLOPHOSPHAMIDE; HYDROGEN PEROXIDE; IRON; ORGANIC CARBON; TITANIUM DIOXIDE; ALKYLATING AGENT; TITANIUM; WASTE WATER; WATER POLLUTANT;

AQUATIC ENVIRONMENT; CONCENTRATION (COMPOSITION); DEGRADATION; DRUG; ECOTOXICOLOGY; MICROBIAL ECOLOGY; OPTIMIZATION; PHOTODEGRADATION; REACTION KINETICS; WATER QUALITY; WATER TREATMENT;

ALIIVIBRIO FISCHERI; AQUATIC ENVIRONMENT; ARTICLE; ASSAY; BACTERIUM; COMPARATIVE STUDY; DEGRADATION; ECOTOXICITY; LIGHT; LIQUID CHROMATOGRAPHY; MINERALIZATION; NONHUMAN; OXIDATION; PHOTODEGRADATION; SCREENING; TANDEM MASS SPECTROMETRY; ULTRAVIOLET RADIATION; WASTE WATER MANAGEMENT; CHEMISTRY; DRUG EFFECTS; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION; PHOTOLYSIS; RADIATION RESPONSE; TOXICITY; WASTE WATER; WATER POLLUTANT;

ALIIVIBRIO FISCHERI; ANTINEOPLASTIC AGENTS, ALKYLATING; CYCLOPHOSPHAMIDE; HYDROGEN PEROXIDE; IRON; KINETICS; OXIDATION-REDUCTION; PHOTOLYSIS; TANDEM MASS SPECTROMETRY; TITANIUM; ULTRAVIOLET RAYS; WASTE WATER; WATER POLLUTANTS, CHEMICAL;

EID: 84912082240     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2014.08.076     Document Type: Article

References (45)

1. Allwood M., Stanley A., Wright P. The Cytotoxics Handbook 2002, Radcliffe Medical Press, England, 512p.
2. APHA/AWWA/WPCF, 2012. Standard Methods for the Examination of Water and Wastewater, v. 22nd, American Water Works Assn, Washington, DC, 1496 p.
3. Arslan-Alaton I., Dogruel S. Pre-treatment of penicillin formulation effluent by advanced oxidation processes. J. Hazard. Mater. 2004, 112:105-113.
4. Arslan-Alaton I., Gurses F. Photo-fenton-like and photo-fenton-like oxidation of Procaine Penicillin G formulation effluent. J. Photochem. Photobiol. A: Chem. 2004, 165:165-175.
5. Augugliaro V., Litter M., Palmisano L., Soria J. The combination of heterogeneous photocatalysis with chemical and physical operations: a tool for improving the photoprocess performance. J. Photochem. Photobiol. C: Photochem. Rev. 2006, 7:127-144.
6. Baumann F., Preiss R. Cyclophosphamide and related anticancer drugs. J. Chromatogr. B: Biomed. Sci. Appl. 2001, 764:173-192.
7. Behnajady M.A., Modirshahla N., Hamzavi R. Kinetic study on photocatalytic degradation of C.I. Acid Yellow 23 by ZnO photocatalyst. J. Hazard. Mater. 2006, 133:226-232.
8. Buerge I.J., Buser H.R., Poiger T., Muller M.D. Occurrence and fate of the cytostatic drugs cyclophosphamide and ifosfamide in wastewater and surface waters. Environ. Sci. Technol. 2006, 40:7242-7250.
9. DeJonge M.E., Huitema A.D., van Dam S.M., Rodenhuis S., Beijnen J.H. Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin. Ther. Drug Monit. 2005, 27:756-765.
10. De la Cruz N., Giménez J., Esplugas S., Grandjean D., de Alencastro L.F., Pulgarín C. Degradation of 32 emergent contaminants by UV and neutral photo-fenton in domestic wastewater effluent previously treated by activated sludge. Water Res. 2012, 46:1947-1957.
11. Eitel A., Scherrer M., Kümmerer K. Handling Cytostatic Drugs: Freiburg 1999, Kehrer Digital & Print, Germany, 42 p.
12. 2 photocatalysis. Desalination 2010, 252:46-52.
13. Fernández L.A., Hernández C., Bataller M., Véliz E., López A., Ledea O., Padrón S. Cyclophosphamide degradation by advanced oxidation processes. Water Environ. J. 2010, 24:174-180.
14. 2 in suspension. Water Res. 2010, 44:5158-5167.
15. Halling-Sørensen B., Nielsen S.N., Lanzky P.F., Ingerslev F., Lützhoft H.C.H., Jorgensen S.E. Occurrence fate and effects of pharmaceutical substances in the environment - a review. Chemosphere 1998, 36:357-393.
16. Hapeshi E., Achilleos A., Vasquez M.I., Michael C., Xekoukoulotakis N.P., Mantzavinos D., Kassinos D. Drugs degrading photocatalytically: kinetics and mechanisms of ofloxacin and atenolol removal on titania suspensions. Water Res. 2010, 44:1737-1746.
17. Heberer T., Ternes T. Residues of pharmaceuticals from human use. Organic Pollutants in Water Cycle 2006, 41-63. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. T. Reemtsma, M. Jekel (Eds.).
18. Hemminki K., Alhonen A., Linkola E., Hesso A. Kinetics of hydrolysis in vitro of nornitrogen mustard, a metabolite of phosphoramide mustard and cyclophosphamide. Arch. Toxicol. 1987, 61:126-130.
19. Hoppe-Tichy T. Current challenges in European oncology pharmacy practice. J. Oncol. Pharm. Pract. 2010, 16:9-18.
20. Kim I., Tanaka H. Photodegradation characteristics of PPCPs in water with UV treatment. Environ. Int. 2009, 35:793-802.
21. Kosjek T., Heath E. Occurrence, fate and determination of cytostatic pharmaceuticals in the environment. TrAC Trends Anal. Chem. 2011, 30:1065-1087.
22. Kümmerer K. Pharmaceuticals in the environment - sources, fate, effects and risks 2008, Springer, Heidelberg, Germany.
23. Kümmerer K. 3.04 - Emerging contaminants. Treatise on Water Science 2011, 69-87. Elsevier, Oxford. W. Peter (Ed.).
24. Kummerer K., Steger-Hartmann T., Baranyai A., Burhaus I. Tests of biodegradation of cytostatics cyclophosphamide and ifosfamide using the Closed Bottle Test (OECD 301 D). Zentralbl Hyg Umweltmed 1996, 198:215-225.
25. Kummerer K., Al-Ahmad A., Bertram B., Wiessler M. Biodegradability of antineoplastic compounds in screening tests: influence of glucosidation and of stereochemistry. Chemosphere 2000, 40:767-773.
26. Lin A.Y.-C., Wang X.-H., Lee W.-N. Phototransformation determines the fate of 5-fluorouracil and cyclophosphamide in natural surface waters. Environ. Sci. Technol. 2013, 47:4104-4112.
27. Litter M.I. Introduction to Photochemical Advanced Oxidation Processes for Water Treatment 2005, Springer, Berlin, Heidelberg, p. 325-366.
28. Llewellyn N., Lloyd P., Jurgens M.D., Johnson A.C. Determination of cyclophosphamide and ifosfamide in sewage effluent by stable isotope-dilution liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2011, 1218:8519-8528.
29. Magdeburg A., Stalter D., Schlüsener M., Ternes T., Oehlmann J. Evaluating the efficiency of advanced wastewater treatment: target analysis of organic contaminants and (geno-)toxicity assessment tell a different story. Water Res. 2014, 50:35-47.
30. Maroga Mboula V., Héquet V., Gru Y., Colin R., Andrès Y. Assessment of the efficiency of photocatalysis on tetracycline biodegradation. J. Hazard. Mater. 2012, 209-210:355-364.
31. Martins R.C., Lopes R.J.G., Quinta-Ferreira R.M. Lumped kinetic models for single ozonation of phenolic effluents. Chem. Eng. J. 2010, 165:678-685.
32. Medana, C., Calza, P., Bello, F.D., Baiocchi, C., Medana, C., Calza, P., Bello, F.D., Baiocchi, C., 2013. LC-HRMS determination of anticancer drugs as occupational contaminants applied to photocatalytic degradation of molecules of different stability. Special Issues.
33. Menz J., Schneider M., Kümmerer K. Toxicity testing with luminescent bacteria - characterization of an automated method for the combined assessment of acute and chronic effects. Chemosphere 2013, 93:990-996.
34. 2 in photo-Fenton reactions using metavanadate. Talanta 2005, 66:86-91.
35. Nussbaumer S., Bonnabry P., Veuthey J.-L., Fleury-Souverain S. Analysis of anticancer drugs: a review. Talanta 2011, 85:2265-2289.
36. Rowney N.C., Johnson A.C., Williams R.J. Cytotoxic drugs in drinking water: a prediction and risk assessment exercise for the thames catchment in the United Kingdom. Environ. Toxicol. Chem. 2009, 28:2733-2743.
37. Sleman F., Mahmoud W.M.M., Schubert R., Kümmerer K. Photodegradation, photocatalytic, and aerobic biodegradation of sulfisomidine and identification of transformation products by LC-UV-MS/MS. CLEAN - Soil, Air, Water 2012, 40:1244-1249.
38. Steger-Hartmann T., Kümmerer K., Hartmann A. Biological degradation of cyclophosphamide and its occurrence in sewage water. Ecotoxicol. Environ. Safety 1997, 36:174-179.
39. 2 molar concentration ratio at different pH values on cyclophosphamide degradation. J. Water Supply: Res. Technol. - AQUA 2005, 403-410.
40. Wang X.-H., Lin A.Y.-C. Is the phototransformation of pharmaceuticals a natural purification process that decreases ecological and human health risks?. Environ. Pollut. 2014, 186:203-215.
41. Wang L., Albasi C., Faucet-Marquis V., Pfohl-Leszkowicz A., Dorandeu C., Marion B., Causserand C. Cyclophosphamide removal from water by nanofiltration and reverse osmosis membrane. Water Res. 2009, 43:4115-4122.
42. 2. Water Res. 2013, 47:5876-5888.
43. 2 photocatalysis. Water Res. 2008, 42:3480-3488.
44. Zhang J., Chang V.W.C., Giannis A., Wang J.-Y. Removal of cytostatic drugs from aquatic environment: a review. Sci. Total Environ. 2013, 445-446:281-298.
45. Zounkova R., Kovalova L., Blaha L., Dott W. Ecotoxicity and genotoxicity assessment of cytotoxic antineoplastic drugs and their metabolites. Chemosphere 2010, 81:253-260.