Design, synthesis, fabrication and in vitro evalution of mucoadhesive 5-amino-2-mercaptobenzimidazole chitosan as low water soluble drug carriers

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 3, 2014, Pages 986-997

  Kongsong, Mullika ^a   Songsurang, Kultida ^a   Sangvanich, Polkit ^a   Siralertmukul, Krisana ^a   Muangsin, Nongnuj ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Drug carrier; Electrospray; Low water soluble drug; Microspheres; Mucoadhesive chitosan; Thiolated chitosan

Indexed keywords

5 AMINO 2 MERCAPTOBENZIMIDAZOLE; ACRYLIC ACID METHYL ESTER; BENZIMIDAZOLE DERIVATIVE; CHITOSAN; DRUG CARRIER; MICROSPHERE; MUCIN; POLYMER; SIALIC ACID; SIMVASTATIN; THIOL GROUP; UNCLASSIFIED DRUG; 2-MERCAPTOBENZIMIDAZOLE; WATER;

ANALYTIC METHOD; ARTICLE; CHEMICAL STRUCTURE; COLORIMETRY; CROSS LINKING; DISULFIDE BOND; DRUG DESIGN; DRUG SOLUBILITY; DRUG SYNTHESIS; ELECTROSPRAY; ELLMAN METHOD; ENCAPSULATION; HYDROGEN BOND; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; MICHAEL ADDITION; MUCOADHESION; PARTICLE SIZE; PH; PROTON NUCLEAR MAGNETIC RESONANCE; STATIC ELECTRICITY; SUSTAINED DRUG RELEASE; THERMOSTABILITY; WATER LOSS; WATER SWELLING; WATER TRANSPORT; ZETA POTENTIAL; ADHESION; CHEMISTRY; DRUG SCREENING; METABOLISM; PROCEDURES; SYNTHESIS;

ADHESIVENESS; BENZIMIDAZOLES; CHITOSAN; DRUG CARRIERS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; MUCINS; WATER;

EID: 84912064651     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.08.016     Document Type: Article

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