Sex steroid blockade enhances thymopoiesis by modulating Notch signaling

Journal of Experimental Medicine

Volumn 211, Issue 12, 2014, Pages 2341-2349

  Velardi, Enrico ^a,b   Tsai, Jennifer J ^a,c   Holland, Amanda M ^a,c,d   Wertheimer, Tobias ^a,e   Yu, Vionnie W C ^f,g,h   Zakrzewski, Johannes L ^a   Tuckett, Andrea Z ^a   Singer, Natalie V ^a   West, Mallory L ^a   Smith, Odette M ^a   Young, Lauren F ^a   Kreines, Fabiana M ^a   Levy, Emily R ^a   Boyd, Richard L ⁱ   Scadden, David T ^f,g,h   Dudakov, Jarrod A ^a,i   van den Brink, Marcel R M ^a,c  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF PERUGIA   (Italy)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e UNIVERSITY OF FREIBURG   (Germany)

^f MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^g HARVARD STEM CELL INSTITUTE   (United States)

^h Harvard University   (United States)

ⁱ MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN AGONIST; GONADORELIN RECEPTOR; NOTCH RECEPTOR; SEX HORMONE; ANDROGEN RECEPTOR; ANDROSTANOLONE; DLL4 PROTEIN, MOUSE; ENZALUTAMIDE; HORMONE ANTAGONIST; MEMBRANE PROTEIN; PHENYLTHIOHYDANTOIN; SIGNAL PEPTIDE; TESTOSTERONE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL REGENERATION; CONTROLLED STUDY; CORTICAL THYMIC EPITHELIAL CELL; DLL4 GENE; FEMALE; GENE; GENE EXPRESSION; GOLD STANDARD; IMMUNE INJURY; LYMPHOPOIESIS; MALE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; STEM CELL; T LYMPHOCYTE; THYMOCYTE; THYMOPOIESIS; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; C57BL MOUSE; CELL LINE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; EPITHELIUM CELL; FLOW CYTOMETRY; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; THYMUS;

ANIMALS; CELL LINE; DIHYDROTESTOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FEMALE; FLOW CYTOMETRY; GONADAL STEROID HORMONES; HEK293 CELLS; HORMONE ANTAGONISTS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOPOIESIS; MALE; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENYLTHIOHYDANTOIN; RECEPTORS, ANDROGEN; RECEPTORS, LHRH; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TESTOSTERONE; THYMOCYTES; THYMUS GLAND;

EID: 84911946540     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131289     Document Type: Article

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