The CpxR/CpxA Two-component regulatory system up-regulates the multidrug resistance cascade to facilitate Escherichia coli resistance to a model antimicrobial peptide

Journal of Biological Chemistry

Volumn 289, Issue 47, 2014, Pages 32571-32582

  Weatherspoon Griffin, Natasha ^a,e   Yang, Dezhi ^a,b,c   Kong, Wei ^b   Hua, Zichun ^d   Shi, Yixin ^a,b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b Arizona State University   (United States)

^c INNER MONGOLIA UNIVERSITY   (China)

^d NANJING UNIVERSITY   (China)

^e UNIVERSITY OF NEVADA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASCADE CONTROL SYSTEMS; MICROORGANISMS; PEPTIDES; POLYPEPTIDES;

ANTIMICROBIAL PEPTIDE; BACTERIAL RESISTANCE; CASCADE CONTROL; E. COLI; MULTIDRUG RESISTANCE; MULTIDRUG TRANSPORTERS; REGULATORY MECHANISM; TWO-COMPONENT REGULATORY SYSTEMS;

ESCHERICHIA COLI;

DEOXYRIBONUCLEASE I; MULTIDRUG RESISTANCE PROTEIN; PROTAMINE; PROTEIN ACRAB; PROTEIN CPXA; PROTEIN CPXR; PROTEIN EMRAB; REGULATOR PROTEIN; TOLC PROTEIN; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL PROTEIN; CARRIER PROTEIN; CPXA PROTEIN, E COLI; CPXR PROTEIN, BACTERIA; DNA BINDING PROTEIN; ESCHERICHIA COLI PROTEIN; MARA PROTEIN, E COLI; MARR PROTEIN, E COLI; OUTER MEMBRANE PROTEIN; PHOSPHOTRANSFERASE; PROTEIN BINDING; PROTEIN KINASE; REPRESSOR PROTEIN; SHIKIMATE KINASE; TOLC PROTEIN, E COLI;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; AROK GENE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BINDING SITE; CONTROLLED STUDY; CPXP GENE; DEGP GENE; ESCHERICHIA COLI; GENE EXPRESSION; MAR GENE; MULTIDRUG RESISTANCE; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; TOLC GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; BIOLOGICAL MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROBIAL VIABILITY; MUTATION; SIGNAL TRANSDUCTION;

ESCHERICHIA COLI;

ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; DNA-BINDING PROTEINS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; MEMBRANE TRANSPORT PROTEINS; MICROBIAL VIABILITY; MODELS, GENETIC; MUTATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROMOTER REGIONS, GENETIC; PROTAMINES; PROTEIN BINDING; PROTEIN KINASES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84911919911     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.565762     Document Type: Article

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