Antibacterial dental composites with chlorhexidine and mesoporous silica

Journal of Dental Research

Volumn 93, Issue 12, 2014, Pages 1283-1289

  Zhang, J F ^a   Wu, R ^a   Fan, Y ^a   Liao, S ^a   Wang, Y ^a   Wen, Z T ^a   Xu, X ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

bacteria; biofilm; controlled release; mechanical properties; Streptococcus mutans; surface roughness

Indexed keywords

ANTIINFECTIVE AGENT; BISPHENOL A BIS(2 HYDROXYPROPYL) ETHER DIMETHACRYLATE; CHLORHEXIDINE; DELAYED RELEASE FORMULATION; DENTAL MATERIAL; ETHOXYLATED BIS-PHENOL A DIMETHACRYLATE; GLASS; METHACRYLIC ACID DERIVATIVE; NANOPARTICLE; POLYURETHAN; RESIN; SBA-15; SILANE DERIVATIVE; SILICON DIOXIDE; URETHANE DIMETHACRYLATE LUTING RESIN;

BIOFILM; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; HUMAN; LACTOBACILLUS CASEI; MATERIALS TESTING; MECHANICAL STRESS; PLIABILITY; POROSITY; STREPTOCOCCUS MUTANS; SURFACE PROPERTY; SYNTHESIS; YOUNG MODULUS;

ANTI-BACTERIAL AGENTS; BIOFILMS; BISPHENOL A-GLYCIDYL METHACRYLATE; CHLORHEXIDINE; COMPOSITE RESINS; DELAYED-ACTION PREPARATIONS; DENTAL MATERIALS; ELASTIC MODULUS; GLASS; HUMANS; LACTOBACILLUS CASEI; MATERIALS TESTING; METHACRYLATES; NANOPARTICLES; PLIABILITY; POLYURETHANES; POROSITY; SILANES; SILICON DIOXIDE; STREPTOCOCCUS MUTANS; STRESS, MECHANICAL; SURFACE PROPERTIES;

EID: 84911914059     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034514555143     Document Type: Article

References (31)

1. Achong RA, Briskie DM, Hildebrandt GH, Feigal RJ, Loesche WJ. Effect of chlorhexidine varnish mouthguards on the levels of selected oral microorganisms in pediatric patients. Pediatr Dent. 1999 ; 21: 169-175
2. Anusavice KJ, Zhang NZ, Shen C. Controlled release of chlorhexidine from UDMA-TEGDMA resin. J Dent Res. 2006 ; 85: 950-954
3. Bekhuis T. Chlorhexidine varnish prevent dental caries in children and adolescents. J Evid Based Dent Pract. 2011 ; 11: 84-86
4. Bitoun JP, Nguyen AH, Fan Y, Burne RA, Wen ZT. Transcriptional repressor Rex is involved in regulation of oxidative stress response and biofilm formation by Streptococcus mutans. FEMS Microbiol Lett. 2011 ; 320: 110-117
5. Bowen RL, Reed LE. Semiporous reinforcing fillers for composite resins: I. Preparation of provisional glass formulations. J Dent Res. 1976 ; 55: 738-747
6. Carpenter AW, Reighard KP, Saavedra JE, Schoenfisch MH. O2-Protected diazeniumdiolate-modified silica nanoparticles for extended nitric oxide release from dental composites. Biomater Sci. 2013 ; 1: 456-459
7. Carriazo D, Arco MD, Fernandez A, Martin C, Rives V. Inclusion and release of fenbufen in mesoporous silica. J Pharm Sci. 2010 ; 99: 3372-3380
8. Chen F, Rice KC, Liu XM, Reinhardt RA, Bayles KW, Wang D. Triclosan-loaded tooth-binding micelles for prevention and treatment of dental biofilm. Pharm Res. 2010 ; 27: 2356-2364
9. Cheng L, Weir MD, Xu HH, Kraigsley AM, Lin NJ, Lin-Gibson S, et al. Antibacterial and physical properties of calcium-phosphate and calcium-fluoride nanocomposites with chlorhexidine. Dent Mater. 2012 ; 28: 573-583
10. Deligeorgi V, Mjör IA, Wilson NH. An overview of reasons for the placement and replacement of restorations. Prim Dent Care. 2001 ; 8: 5-11
11. Imazato S. Bio-active restorative materials with antibacterial effects: new dimension of innovation in restorative dentistry. Dent Mater J. 2009 ; 28: 11-19
12. Izquierdo-Barba I, Vallet-Regi M, Kupferschmidt N, Terasaki O, Schmidtchen A, Malmsten M. Incorporation of antimicrobial compounds in mesoporous silica film monolith. Biomaterials. 2009 ; 30: 5729-5736
13. Järvinen H, Tenovuo J, Huovinen P. In vitro susceptibility of Streptococcus mutans to chlorhexidine and six other antimicrobial agents. Antimicrob Agents Chemother. 1993 ; 37: 1158-1159
14. Jedrychowski JR, Caputo AA, Kerper A. Antibacterial and mechanical properties of restorative materials combined with chlorhexidines. J Oral Rehabil. 1983 ; 10: 373-381
15. Jokstad A, Bayne S, Blunck U, Tyas M, Wilson N. Quality of dental restorations - FDI Commission Project 2-95. Int Dent J. 2001 ; 51: 117-158
16. Leung D, Spratt DA, Pratten J, Gulabivala K, Mordan NJ, Young AM. Chlorhexidine-releasing methacrylate dental composite materials. Biomaterials. 2005 ; 26: 7145-7153
17. Liong M, France B, Bradley KA, Zink JI. Antimicrobial activity of silver nanocrystals encapsulated in mesoporous silica nanoparticles. Adv Mater. 2009 ; 21: 1684-1689
18. Luo JH, Lannutti JJ, Seghi RR. Effect of filler porosity on the abrasion resistance of nanoporous silica gel/polymer composites. Dent Mater. 1998 ; 14: 29-36
19. Mjör IA, Moorhead JE, Dahl JE. Reasons for replacement of restorations in permanent teeth in general dental practice. Int Dent J. 2000 ; 50: 361-366
20. Petkar KC, Chavhan SS, Agatonovik-Kustrin S, Sawant KK. Nanostructured materials in drug and gene delivery: a review of the state of the art. Crit Rev Ther Drug Carrier Syst. 2011 ; 28: 101-164
21. Praveen S, Sun Z, Xu J, Patel A, Wei Y, Ranade R, et al. Compression and aging properties of experimental dental composites containing mesoporous silica as fillers. Mol Cryst Liq Cryst. 2006 ; 448: 223-231
22. Raso EM, Cortes ME, Teixeira KL, Franco MB, Mohallem ND, Sinisterra RD. A new controlled release system of chlorhexidine and chlorhexidine:βcd inclusion compounds based on porous silica. J Incl Phenom Macro. 2010 ; 67: 159-168
23. Riggs PD, Braden M, Patel M. Chlorhexidine release from room temperature polymerising methacrylate systems. Biomaterials. 2000 ; 21: 345-351
24. Samuel SP, Li S, Mukherjee I, Guo Y, Patel AC, Baran G, et al. Mechanical properties of experimental dental composites containing a combination of mesoporous and nonporous spherical silica as fillers. Dent Mater. 2009 ; 25: 296-301
25. Slot DE, Vaandrager NC, Van Loveren C, Van Palenstein Helderman WH, Van der Weijden GA. The effect of chlorhexidine varnish on root caries: a systematic review. Caries Res. 2011 ; 45: 162-173
26. Wen ZT, Burne RA. Functional genomics approach to identifying genes required for biofilm development by Streptococcus mutans. Appl Environ Microbiol. 2002 ; 68: 1196-1203
27. Wen ZT, Burne RA. LuxS-mediated signaling in Streptococcus mutans is involved in regulation of acid and oxidative stress tolerance and biofilm formation. J Bacteriol. 2004 ; 186: 2682-2691
28. Wen ZT, Yates D, Ahn SJ, Burne RA. Biofilm formation and virulence expression by Streptococcus mutans are altered when grown in dual-species model. BMC Microbiol. 2010 ; 10: 111
29. Xu X, Ling L, Wang R, Burgess JO. Formulation and characterization of a novel fluoride-releasing dental composite. Dent Mater. 2006 ; 22: 1014-1023
30. Xu X, Wang Y, Liao S, Wen Z, Fan Y. Synthesis and characterization of antibacterial dental monomers and composites. J Biomed Mater Res B Appl Biomater. 2012 ; 100: 1151-1162
31. Zhao D, Feng J, Huo Q, Melosh N, Fredrickson GH, Chmelka BF, et al. Triblock copolymer syntheses of mesoporous silica with periodic 50 to 300 Ångström pores. Science. 1998 ; 279: 548-552