Concurrent middle cerebral artery occlusion and intra-arterial drug infusion via ipsilateral common carotid artery catheter in the rat

Journal of Neuroscience Methods

Volumn 213, Issue 1, 2013, Pages 63-69

  Van Winkle, Jessica A ^a   Chen, Bo ^a   Lei, I Farn ^a   Pereira, Benedict ^a   Rajput, Padmesh S ^a   Lyden, Patrick D ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Cerebral ischemia; Drug delivery; Intraluminal filament; Middle cerebral artery occlusion; Stroke

Indexed keywords

EVANS BLUE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CATHETER; ARTERY CATHETERIZATION; ARTICLE; COMMON CAROTID ARTERY; CONTROLLED STUDY; DRUG INFUSION; HEMISPHERE; INDWELLING CATHETER; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTROPHOTOMETER;

ANESTHESIA; ANIMALS; BRAIN ISCHEMIA; CAROTID ARTERY, COMMON; CATHETERIZATION, PERIPHERAL; COLORING AGENTS; EVANS BLUE; FUNCTIONAL LATERALITY; INFARCTION, MIDDLE CEREBRAL ARTERY; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRA-ARTERIAL; JUGULAR VEINS; MALE; NEUROLOGIC EXAMINATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION; STROKE; SUTURES;

EID: 84871976420     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2012.12.004     Document Type: Article

References (13)

1. Alavijeh M.S., Chishty M., Qaiser M.Z., Palmer A.M. Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery. NeuroRx 2005, 2:554-571.
2. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 1986, 17:472-476.
3. Belayev L., Alonso O.F., Busto R., Zhao W., Ginsberg M.D. Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 1996, 27:1616-1622. discussion 23.
4. Chen B., Cheng Q., Yang K., Lyden P.D. Thrombin mediates severe neurovascular injury during ischemia. Stroke 2010, 41:2348-2352.
5. Chen B., Friedman B., Whitney M.A., Winkle J.A., Lei I.F., Olson E.S., et al. Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci 2012, 32:7622-7631.
6. Fisher M., Tatlisumak T. Use of animal models has not contributed to development of acute stroke therapies: con. Stroke 2005, 36:2324-2325.
7. Heiser A. Rat Jugular Vein and Carotid Artery Catheterization for Acute Survival Studies 2007, vol. 33. Spring Science+Business Media, New York, pp. 7-48.
8. Joshi S., Meyers P.M., Ornstein E. Intracarotid delivery of drugs: the potential and the pitfalls. Anesthesiology 2008, 109:543-564.
9. Kawaguchi M., Furuya H., Patel P.M. Neuroprotective effects of anesthetic agents. J Anesth 2005, 19:150-156.
10. Kaya M., Ahishali B. Assessment of permeability in barrier type of endothelium in brain using tracers: Evans blue, sodium fluorescein, and horseradish peroxidase. Methods Mol Biol 2011, 763:369-382.
11. Macrae I.M. Preclinical stroke research-advantages and disadvantages of the most common rodent models of focal ischaemia. Br J Pharmacol 2011, 164:1062-1078.
12. Tymianski M. Can molecular and cellular neuroprotection be translated into therapies for patients?: yes, but not the way we tried it before. Stroke 2010, 41:S87-S90.
13. Yang G.Y., Betz A.L. Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats. Stroke 1994, 25:1658-1664. discussion 64-5.