Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling

Biochemical Journal

Volumn 464, Issue 2, 2014, Pages 179-192

  Yang, Wulin ^a   Thein, Shermaine ^a   Lim, Chun Yan ^a,b   Ericksen, Russell E ^a   Sugii, Shigeki ^a   Xu, Feng ^c   Robinson, Robert C ^b,d   Kim, Jae Bum ^e   Han, Weiping ^a,b,d,e  

^a Laboratory of Metabolic Medicine   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c AGENCY FOR SCIENCE   (Singapore)

^d INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^e Seoul National University   (South Korea)

Author keywords

Actin remodelling; Actin related protein 2 3 (Arp2 3); Adipogenesis; Insulin signalling; Nucleation

Indexed keywords

ACTIN; ACTIN RELATED PROTEIN 2-3 COMPLEX; CORTICAL ACTIN; F ACTIN; GLUCOSE TRANSPORTER 4; INSULIN; UNCLASSIFIED DRUG; ACTIN RELATED PROTEIN 2; ACTIN RELATED PROTEIN 3;

ACTIN FILAMENT; ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL MEMBRANE; CELL STRUCTURE; CONTROLLED STUDY; EXOCYTOSIS; MOUSE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; GENETICS; METABOLISM;

ACTIN CYTOSKELETON; ACTIN-RELATED PROTEIN 2; ACTIN-RELATED PROTEIN 2-3 COMPLEX; ACTIN-RELATED PROTEIN 3; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CELL DIFFERENTIATION; GLUCOSE TRANSPORTER TYPE 4; INSULIN; MICE; SIGNAL TRANSDUCTION;

EID: 84911873017     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140805     Document Type: Article

References (35)

1. Cristancho, A. G. and Lazar, M. A. (2011) Forming functional fat: a growing understanding of adipocyte differentiation. Nat. Rev. Mol. Cell Biol. 12, 722-734 CrossRef PubMed
2. Coppari, R. and Bjorbaek, C. (2012) Leptin revisited: its mechanism of action and potential for treating diabetes. Nat. Rev. Drug Discov. 11, 692-708 CrossRef PubMed
3. Yamauchi, T. and Kadowaki, T. (2013) Adiponectin receptor as a key player in healthy longevity and obesity-related diseases. Cell Metab. 17, 185-196 CrossRef PubMed
4. Zeve, D., Tang, W. and Graff, J. (2009) Fighting fat with fat: the expanding field of adipose stem cells. Cell Stem Cell 5, 472-481 CrossRef PubMed
5. Rosen, E. D. and MacDougald, O. A. (2006) Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol. 7, 885-896 CrossRef PubMed
6. Yang, W., Guo, X., Thein, S., Xu, F., Sugii, S., Baas, P. W., Radda, G. K. and Han, W. (2013) Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of alpha-tubulin. Biochem. J. 449, 605-612 CrossRef PubMed
7. Yang, W., Thein, S., Wang, X., Bi, X., Ericksen, R. E., Xu, F. and Han, W. (2014) BSCL2/seipin regulates adipogenesis through actin cytoskeleton remodelling. Hum. Mol. Genet. 23, 502-513 CrossRef PubMed
8. Kanzaki, M. (2006) Insulin receptor signals regulating GLUT4 translocation and actin dynamics. Endocr. J. 53, 267-293 CrossRef PubMed
9. Yang, W., Thein, S., Guo, X., Xu, F., Venkatesh, B., Sugii, S., Radda, G. K. and Han, W. (2013) Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus. Biochem. J. 452, 37-44 PubMed
10. Pang, Z. P., Cao, P., Xu, W. and Sudhof, T. C. (2010) Calmodulin controls synaptic strength via presynaptic activation of calmodulin kinase II. J. Neurosci. 30, 4132-4142 CrossRef PubMed
11. Steffen, A., Faix, J., Resch, G. P., Linkner, J., Wehland, J., Small, J. V., Rottner, K. and Stradal, T. E. (2006) Filopodia formation in the absence of functional WAVE-and Arp2/3-complexes. Mol. Biol. Cell 17, 2581-2591 CrossRef PubMed
12. Korobova, F. and Svitkina, T. (2008) Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cells. Mol. Biol. Cell 19, 1561-1574 CrossRef PubMed
13. Sugii, S., Kida, Y., Berggren, W. T. and Evans, R. M. (2011) Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells. Nat. Protoc. 6, 346-358 CrossRef PubMed
14. Gregoire, F. M., Smas, C. M. and Sul, H. S. (1998) Understanding adipocyte differentiation. Physiol. Rev. 78, 783-809 PubMed
15. Rotty, J. D., Wu, C. and Bear, J. E. (2013) New insights into the regulation and cellular functions of the ARP2/3 complex. Nat. Rev. Mol. Cell Biol. 14, 7-12 CrossRef PubMed
16. Robinson, R. C., Turbedsky, K., Kaiser, D. A., Marchand, J. B., Higgs, H. N., Choe, S. and Pollard, T. D. (2001) Crystal structure of Arp2/3 complex. Science 294, 1679-1684 CrossRef PubMed
17. Lopez, J. A., Burchfield, J. G., Blair, D. H., Mele, K., Ng, Y., Vallotton, P., James, D. E. and Hughes, W. E. (2009) Identification of a distal GLUT4 trafficking event controlled by actin polymerization. Mol. Biol. Cell 20, 3918-3929 CrossRef PubMed
18. Bose, A., Guilherme, A., Robida, S. I., Nicoloro, S. M., Zhou, Q. L., Jiang, Z. Y., Pomerleau, D. P. and Czech, M. P. (2002) Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c. Nature 420, 821-824 CrossRef PubMed
19. Kanzaki, M. and Pessin, J. E. (2001) Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling. J. Biol. Chem. 276, 42436-42444 CrossRef PubMed
20. Kanzaki, M., Furukawa, M., Raab, W. and Pessin, J. E. (2004) Phosphatidylinositol 4, 5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling. J. Biol. Chem. 279, 30622-30633 CrossRef PubMed
21. Kubota, T., Kubota, N. and Kadowaki, T. (2013) The role of endothelial insulin signaling in the regulation of glucose metabolism. Rev. Endocr. Metab. Disord. 14, 207-216 CrossRef PubMed
22. Zhang, B., Berger, J., Zhou, G., Elbrecht, A., Biswas, S., White-Carrington, S., Szalkowski, D. and Moller, D. E. (1996) Insulin-and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ. J. Biol. Chem. 271, 31771-31774 CrossRef PubMed
23. Prusty, D., Park, B. H., Davis, K. E. and Farmer, S. R. (2002) Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator-activated receptor γ (PPARγ) and C/EBPα gene expression during the differentiation of 3T3-L1 preadipocytes. J. Biol. Chem. 277, 46226-46232 CrossRef PubMed
24. Omata, W., Shibata, H., Li, L., Takata, K. and Kojima, I. (2000) Actin filaments play a critical role in insulin-induced exocytotic recruitment but not in endocytosis of GLUT4 in isolated rat adipocytes. Biochem. J. 346, 321-328 CrossRef PubMed
25. Clark, S. F., Martin, S., Carozzi, A. J., Hill, M. M. and James, D. E. (1998) Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton. J. Cell Biol. 140, 1211-1225 CrossRef PubMed
26. Bisi, S., Disanza, A., Malinverno, C., Frittoli, E., Palamidessi, A. and Scita, G. (2013) Membrane and actin dynamics interplay at lamellipodia leading edge. Curr. Opin. Cell Biol. 25, 565-573 CrossRef PubMed
27. Murphy, D. A. and Courtneidge, S. A. (2011) The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function. Nat. Rev. Mol. Cell Biol. 12, 413-426 CrossRef PubMed
28. Fehrenbacher, K., Huckaba, T., Yang, H. C., Boldogh, I. and Pon, L. (2003) Actin comet tails, endosomes and endosymbionts. J. Exp. Biol. 206, 1977-1984 CrossRef PubMed
29. Yi, K., Unruh, J. R., Deng, M., Slaughter, B. D., Rubinstein, B. and Li, R. (2011) Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes. Nat. Cell Biol. 13, 1252-1258 CrossRef PubMed
30. Yang, Q., Zhang, X. F., Pollard, T. D. and Forscher, P. (2012) Arp2/3 complex-dependent actin networks constrain myosin II function in driving retrograde actin flow. J. Cell Biol. 197, 939-956 CrossRef PubMed
31. Rajan, A., Tien, A. C., Haueter, C. M., Schulze, K. L. and Bellen, H. J. (2009) The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors. Nat. Cell Biol. 11, 815-824 CrossRef PubMed
32. Zhou, K., Muroyama, A., Underwood, J., Leylek, R., Ray, S., Soderling, S. H. and Lechler, T. (2013) Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation. Proc. Natl Acad. Sci. U. S. A. 110, E3820-E3829 CrossRef PubMed
33. Gowrishankar, K., Ghosh, S., Saha, S. C. R., Mayor, S. and Rao, M. (2012) Active remodeling of cortical actin regulates spatiotemporal organization of cell surface molecules. Cell 149, 1353-1367 CrossRef PubMed
34. Chen, G., Raman, P., Bhonagiri, P., Strawbridge, A. B., Pattar, G. R. and Elmendorf, J. S. (2004) Protective effect of phosphatidylinositol 4, 5-bisphosphate against cortical filamentous actin loss and insulin resistance induced by sustained exposure of 3T3-L1 adipocytes to insulin. J. Biol. Chem. 279, 39705-39709 CrossRef PubMed
35. Brozinick, Jr, J. T., Hawkins, E. D., Strawbridge, A. B. and Elmendorf, J. S. (2004) Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues. J. Biol. Chem. 279, 40699-40706 CrossRef PubMed