Human adipose tissue-derived mesenchymal stromal cells promote B-cell motility and chemoattraction

Cytotherapy

Volumn 16, Issue 12, 2014, Pages 1692-1699

  Barrio, Laura ^a   Cuevas, Victor Delgado ^a   Menta, Ramón ^b   Mancheño Corvo, Pablo ^b   delaRosa, Olga ^b   Dalemans, Wilfried ^c   Lombardo, Eleuterio ^b   Carrasco, Yolanda R ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b Parque Tecnologico de Madrid   (Spain)

^c TiGenix   (Belgium)

Author keywords

B cells; Chemotaxis; Mesenchymal stromal cells; Migration

Indexed keywords

CHEMOKINE; CHEMOTACTIC FACTOR; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN E2; RANTES; STROMAL CELL DERIVED FACTOR 1; IL8 PROTEIN, HUMAN;

ADIPOSE DERIVED STEM CELL; ADULT; ARTICLE; B LYMPHOCYTE; CELL CONTACT; CELL MIGRATION; CELL MOTILITY; CELL STIMULATION; CELL SURVIVAL; CHEMOTAXIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; LONG TERM EXPOSURE; MESENCHYMAL STROMA CELL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; ADIPOSE TISSUE; CELL CULTURE; COCULTURE; CYTOLOGY; FEMALE; MALE; METABOLISM; SECRETION (PROCESS);

ADIPOSE TISSUE; B-LYMPHOCYTES; CELLS, CULTURED; CHEMOTAXIS; COCULTURE TECHNIQUES; DINOPROSTONE; FEMALE; HUMANS; INTERLEUKIN-8; MALE; MESENCHYMAL STROMAL CELLS;

EID: 84911868848     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2014.07.012     Document Type: Article

References (36)

1. Uccelli A., Moretta L., Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol 2008, 8:726-736.
2. Shi Y., Su J., Roberts A.I., Shou P., Rabson A.B., Ren G. How mesenchymal stem cells interact with tissue immune responses. Trends Immunol 2012, 33:136-143.
3. Ren G., Su J., Zhang L., Zhao X., Ling W., L'Huillie A., et al. Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression. Stem Cells 2009, 27:1954-1962.
4. Duffy M.M., Ritter T., Ceredig R., Griffin M.D. Mesenchymal stem cell effects on T-cell effector pathways. Stem Cell Res Ther 2011, 2:34.
5. Spaggiari G.M., Capobianco A., Abdelrazik H., Becchetti F., Mingari M.C., Moretta L. Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2. Blood 2008, 111:1327-1333.
6. Spaggiari G.M., Abdelrazik H., Becchetti F., Moretta L. MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2. Blood 2009, 113:6576-6583.
7. Chiesa S., Morbelli S., Morando S., Massollo M., Marini C., Bertoni A., et al. Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells. Proc Natl Acad Sci U S A 2011, 108:17384-17389.
8. Francois M., Romieu-Mourez R., Li M., Galipeau J. Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation. Mol Ther 2012, 20:187-195.
9. Edwards J.C., Cambridge G. B-cell targeting in rheumatoid arthritis and other autoimmune diseases. Nat Rev Immunol 2006, 6:394-403.
10. Shlomchik M.J. Activating systemic autoimmunity: B's, T's, and tolls. Curr Opin Immunol 2009, 21:626-633.
11. Green N.M., Marshak-Rothstein A. Toll-like receptor driven B cell activation in the induction of systemic autoimmunity. Semin Immunol 2011, 23:106-112.
12. Franquesa M., Hoogduijn M.J., Bestard O., Grinyo J.M. Immunomodulatory effect of mesenchymal stem cells on B cells. Front Immunol 2012, 3:212.
13. Corcione A., Benvenuto F., Ferretti E., Giunti D., Cappiello V., Cazzanti F., et al. Human mesenchymal stem cells modulate B-cell functions. Blood 2006, 107:367-372.
14. Rasmusson I., Uhlin M., Le Blanc K., Levitsky V. Mesenchymal stem cells fail to trigger effector functions of cytotoxic T lymphocytes. JLeukoc Biol 2007, 82:887-893.
15. Bochev I., Elmadjian G., Kyurkchiev D., Tzvetanov L., Altankova I., Tivchev P., et al. Mesenchymal stem cells from human bone marrow or adipose tissue differently modulate mitogen-stimulated B-cell immunoglobulin production in vitro. Cell Biol Int 2008, 32:384-393.
16. Tabera S., Perez-Simon J.A., Diez-Campelo M., Sanchez-Abarca L.I., Blanco B., Lopez A., et al. The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes. Haematologica 2008, 93:1301-1309.
17. Asari S., Itakura S., Ferreri K., Liu C.P., Kuroda Y., Kandeel F., et al. Mesenchymal stem cells suppress B-cell terminal differentiation. Exp Hematol 2009, 37:604-615.
18. Schena F., Gambini C., Gregorio A., Mosconi M., Reverberi D., Gattorno M., et al. Interferon-gamma-dependent inhibition of B cell activation by bone marrow-derived mesenchymal stem cells in a murine model of systemic lupus erythematosus. Arthritis Rheum 2010, 62:2776-2786.
19. Lombardo E., DelaRosa O., Mancheno-Corvo P., Menta R., Ramirez C., Buscher D. Toll-like receptor-mediated signaling in human adipose-derived stem cells: implications for immunogenicity and immunosuppressive potential. Tissue Eng Part A 2009, 15:1579-1589.
20. Allen C.D., Cyster J.G. Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function. Semin Immunol 2008, 20:14-25.
21. Perez-Andres M., Paiva B., Nieto W.G., Caraux A., Schmitz A., Almeida J., et al. Human peripheral blood B-cell compartments: a crossroad in B-cell traffic. Cytometry Part B Clin Cytometry 2010, 78(Suppl 1):S47-60.
22. Frade J.M., Mellado M., del Real G., Gutierrez-Ramos J.C., Lind P., Martinez A.C. Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells. JImmunol 1997, 159:5576-5584.
23. Zlotnik A., Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000, 12:121-127.
24. Zonca M., Mancheno-Corvo P., DelaRosa O., Manes S., Buscher D., Lombardo E., et al. APRIL and BAFF proteins increase proliferation of human adipose-derived stem cells through activation of Erk1/2 MAP kinase. Tissue Eng Part A 2012, 18:852-859.
25. Badr G., Borhis G., Lefevre E.A., Chaoul N., Deshayes F., Dessirier V., et al. BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells. Blood 2008, 111:2744-2754.
26. Yanez R., Oviedo A., Aldea M., Bueren J.A., Lamana M.L. Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells. Exp Cell Res 2010, 316:3109-3123.
27. Kobayashi Y. The role of chemokines in neutrophil biology. Front Biosci 2008, 13:2400-2407.
28. Tilley S.L., Coffman T.M., Koller B.H. Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. JClin Invest 2001, 108:15-23.
29. Luft T., Jefford M., Luetjens P., Toy T., Hochrein H., Masterman K.A., et al. Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets. Blood 2002, 100:1362-1372.
30. Diaz-Munoz M.D., Osma-Garcia I.C., Iniguez M.A., Fresno M. Cyclooxygenase-2 deficiency in macrophages leads to defective p110gamma PI3K signaling and impairs cell adhesion and migration. JImmunol 2013, 191:395-406.
31. Hoggatt J., Mohammad K.S., Singh P., Hoggatt A.F., Chitteti B.R., Speth J.M., et al. Differential stem- and progenitor-cell trafficking by prostaglandin E2. Nature 2013, 495:365-369.
32. Ren G., Zhang L., Zhao X., Xu G., Zhang Y., Roberts A.I., et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008, 2:141-150.
33. Rasmusson I., Le Blanc K., Sundberg B., Ringden O. Mesenchymal stem cells stimulate antibody secretion in human B cells. Scand J Immunol 2007, 65:336-343.
34. Nielsen L.S., Frydenberg J., Lind M., Deleuran M., Stengaard-Pedersen K., Deleuran B. CD19-selected B lymphocytes synthesize, secrete and migrate in the presence of IL-8. TNF-alpha and gammaIP-10 are also B lymphocyte migratory factors. Cytokine 1997, 9:747-753.
35. Jinquan T., Moller B., Storgaard M., Mukaida N., Bonde J., Grunnet N., et al. Chemotaxis and IL-8 receptor expression in B cells from normal and HIV-infected subjects. JImmunol 1997, 158:475-484.
36. Magari M., Nishikawa Y., Fujii Y., Nishio Y., Watanabe K., Fujiwara M., et al. IL-21-dependent B cell death driven by prostaglandin E2, a product secreted from follicular dendritic cells. JImmunol 2011, 187:4210-4218.