Efficacy and safety of alirocumab as add-on therapy in high-cardiovascular-risk patients with hypercholesterolemia not adequately controlled with atorvastatin (20 or 40 mg) or rosuvastatin (10 or 20mg): Design and rationale of the odyssey options studies

Clinical Cardiology

Volumn 37, Issue 10, 2014, Pages 597-604

  Robinson, Jennifer G ^a   Colhoun, Helen M ^a   Bays, Harold E ^b   Jones, Peter H ^c   Du, Yunling ^d   Hanotin, Corinne ^e   Donahue, Stephen ^f  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c LOUISVILLE METABOLIC AND ATHEROSCLEROSIS RESEARCH CENTER   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e REGENERON PHARMACEUTICALS INC   (United States)

^f SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALIROCUMAB; APOLIPOPROTEIN B; ATORVASTATIN; EZETIMIBE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ROSUVASTATIN; FLUOROBENZENE; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; MONOCLONAL ANTIBODY; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; SULFONAMIDE;

ADD ON THERAPY; ADULT; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL DECISION MAKING; DIABETES MELLITUS; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); RANDOMIZED CONTROLLED TRIAL (TOPIC); STUDY DESIGN; BLOOD; CARDIOVASCULAR DISEASES; CLINICAL TRIAL; COMBINATION DRUG THERAPY; COMPLICATION; CONTROLLED STUDY; DOSE RESPONSE; MULTICENTER STUDY; PHASE 3 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ANTIBODIES, MONOCLONAL; ANTICHOLESTEREMIC AGENTS; ATORVASTATIN CALCIUM; CARDIOVASCULAR DISEASES; CHOLESTEROL, LDL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; FLUOROBENZENES; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; MALE; PYRIMIDINES; PYRROLES; ROSUVASTATIN CALCIUM; SULFONAMIDES; TREATMENT OUTCOME;

EID: 84911807189     PISSN: 01609289     EISSN: 19328737     Source Type: Journal    
DOI: 10.1002/clc.22327     Document Type: Article

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