Effects of functionalization of PLGA-[Asp-PEG]n copolymer surfaces with Arg-Gly-Asp peptides, hydroxyapatite nanoparticles, and BMP-2-derived peptides on cell behavior in vitro

Journal of Biomedical Materials Research - Part A

Volumn 102, Issue 12, 2014, Pages 4526-4535

  Pan, Haitao ^a   Zheng, Qixin ^a   Yang, Shuhua ^a   Guo, Xiaodong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

BMP 2 derived peptide; Cell behavior; Functionalization of polymer surfaces; Osteoinduction; Polydopamine

Indexed keywords

BIOMOLECULES; BONE; CELL ADHESION; CELL ENGINEERING; CELLS; CHEMICAL MODIFICATION; COPOLYMERS; CYTOLOGY; HYDROXYAPATITE; MOLECULAR BIOLOGY; NANOPARTICLES; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; PROTEINS; REPAIR; STEM CELLS; TISSUE ENGINEERING;

BONE MARROW STROMAL CELLS; BONE MORPHOGENETIC PROTEIN-2; CELL BEHAVIORS; FUNCTIONALIZATION OF POLYMERS; HYDROXYAPATITE NANOPARTICLES; OSTEOINDUCTION; POLYDOPAMINE; SURFACE MODIFICATION TECHNIQUES;

SCAFFOLDS (BIOLOGY);

ARGINYLGLYCYLASPARTIC ACID; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; HYDROXYAPATITE; OSTEOCALCIN; POLYGLACTIN; ANTINEOPLASTIC AGENT; ARGINYL-GLYCYL-ASPARTIC ACID; BMP2 PROTEIN, HUMAN; LACTIC ACID; MACROGOL DERIVATIVE; NANOPARTICLE; OLIGOPEPTIDE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL CELL; ARTICLE; BONE MARROW STROMA CELL; BONE MINERALIZATION; BONE REMODELING; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; EXTRACELLULAR MATRIX; NONHUMAN; POLYMERIZATION; RABBIT; SURFACE PROPERTY; TISSUE ENGINEERING; ANIMAL; BONE MARROW CELL; BONE REGENERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; HUMAN; METABOLISM; STROMA CELL; TISSUE SCAFFOLD;

ANIMALS; ANTINEOPLASTIC AGENTS; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CELL ADHESION; DURAPATITE; HUMANS; LACTIC ACID; NANOPARTICLES; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; RABBITS; STROMAL CELLS; TISSUE SCAFFOLDS;

EID: 84911807152     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35129     Document Type: Article

References (43)

1. Betz RR. Limitations of autograft and allograft: New synthetic solutions. Orthopedics 2002;25 (5 Suppl):561-570.
2. Fröhlich M, Grayson WL, Wan LQ, Marolt D, Drobnic M, Vunjak- Novakovic G. Tissue engineered bone grafts: Biological requirements, tissue culture and clinical relevance. Curr Stem Cell Res Ther 2008;3:254-264.
3. Grabowski G, Cornett CA. Bone graft and bone graft substitutes in spine surgery: Current concepts and controversies. J Am Acad Orthop Surg 2013;21:51-60.
4. Cabraja M, Kroppenstedt S. Bone grafting and substitutes in spine surgery. J Neurosurg Sci 2012;56:87-95.
5. Lin CY, Chang YH, Li KC, Lu CH, Sung LY, Yeh CL, Lin KJ, Huang SF, Yen TC, Hu YC. The use of ASCs engineered to express BMP2 or TGF-b3 within scaffold constructs to promote calvarial bone repair. Biomaterials 2013;34:9401-9412.
6. Liu J, Liu C, Sun B, Shi C, Qiao C, Ke X, Liu S, Liu X, Sun H. Differentiation of rabbit bone mesenchymal stem cells into endothelial cells in vitro and promotion of defective bone regeneration in vivo. Cell Biochem Biophys, in press.
7. Wang DX, He Y, Bi L, Qu ZH, Zou JW, Pan Z, Fan JJ, Chen L, Dong X, Liu XN, Pei GX, Ding JD. Enhancing the bioactivity of Poly(lactic-co-glycolic acid) scaffold with a nano-hydroxyapatite coating for the treatment of segmental bone defect in a rabbit model. Int J Nanomed 2013;8:1855-1865.
8. Luo B, Quan D, Liao K, Lu Z, Zhou C. Synthesis and characterization of novel copolymers containing pendant amine functional groups based on D,L-lactide, glycolide and poly(PEG-co-L-aspartic acid). Acta Polym Sin 2005;1:327-332.
9. Pan H, Zheng Q, Guo X. Experimental studies on a new bone tissue engineered scaffold biomaterials combined with cultured marrow stromal stem cells in vitro. Chin J Reparative Reconstr Surg 2007;21:65-69.
10. Chien CY, Tsai WB. Poly(dopamine)-assisted immobilization of Arg-Gly-Asp peptides, hydroxyapatite, and bone morphogenic protein-2 on titanium to improve the osteogenesis of bone marrow stem cells. ACS Appl Mater Interfaces 2013;5:6975-6983.
11. Foster CM, Collazo R, Sitar Z, Ivanisevic A. Cell behavior on gallium nitride surfaces: Peptide affinity attachment versus covalent functionalization. Langmuir 2013;29:8377-8384.
12. Lee JY, Choi YS, Lee SJ, Chung CP, Park YJ. Bioactive peptidemodified biomaterials for bone regeneration. Curr Pharm Des 2011;17:2663-2676.
13. Rumian L, Wojak I, Scharnweber D, Pamua E. Resorbable scaffolds modified with collagen type I or hydroxyapatite: In vitro studies on human mesenchymal stem cells. Acta Bioeng Biomech 2013;15:61-67.
14. Kuroda K, Okido M. Hydroxyapatite coating of titanium implants using hydroprocessing and evaluation of their osteoconductivity. Bioinorg Chem Appl 2012;2012:730693.
15. Jeon O, Song SJ, Kang SW, Putnam AJ, Kim BS. Enhancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparin-conjugated poly(L-lactic-co-glycolic acid) scaffold. Biomaterials 2007;28:2763-2771.
16. Bae IH, Jeong BC, Kook MS, Kim SH, Koh JT. Evaluation of a thiolated chitosan scaffold for local delivery of BMP-2 for osteogenic differentiation and ectopic bone formation. Biomed Res Int 2013;2013:878930.
17. Qiao C, Zhang K, Jin H, Miao L, Shi C, Liu X, Yuan A, Liu J, Li D, Zheng C, Zhang G, Li X, Yang B, Sun H. Using poly(lactic-co-glycolic acid) microspheres to encapsulate plasmid of bone morphogenetic protein 2/polyethylenimine nanoparticles to promote bone formation in vitro and in vivo. Int J Nanomed 2013;8:2985-2995.
18. Lee H, Dellatore SM, Miller WM, Messersmith PB. Musselinspired surface chemistry for multifunctional coatings. Science 2007;318: 426-430.
19. Kang SM, You I, Cho WK, Shon HK, Lee TG, Choi IS, Karp JM, Lee H. One-step modification of superhydrophobic surfaces by a mussel-inspired polymer coating. Angew Chem Int Ed Engl 2010; 49:9401-9404.
20. Lee H, Rho J, Messersmith PB. Facile conjugation of biomolecules onto surfaces via mussel adhesive protein inspired coatings. Adv Mater 2009;21:431-434.
21. Ham HO, Liu Z, Lau KH, Lee H, Messersmith PB. Facile DNA immobilization on surfaces through a catecholamine polymer. Angew Chem Int Ed Engl 2011;50:732-736.
22. Orive AG, Creus AH, Grumelli D, Benitez GA, Andrini L, Requezo FG, Bonazzola C, Salvarezza RC. Oxygen reduction on ironmelanin granular surfaces. J Phys Chem C 2009;113:17097-17103.
23. Ku SH, Ryu J, Hong SK, Lee H, Park CB. General functionalization route for cell adhesion on non-wetting surfaces. Biomaterials 2010;31:2535-2341.
24. Ye W, Wang D, Zhang H, Zhou F, Liu W. Electrochemical growth of flowerlike gold nanoparticles on polydopamine modified ITO glass for SERS application. Electrochem Acta 2010;55:2004-2009.
25. Mikos AG, Thorsen AJ, Czerwonka LA, Bao Y, Langer R, Winslow DN, Vacanti JP. Preparation and characterization of poly(L-lactic acid) foams. Polymer 1994;35:1068-1077.
26. Harbottle RP, Cooper RG, Hart SL, Ladhoff A, McKay T, Knight AM, Wagner E, Miller AD, Coutelle C. An RGD-Oligolysine peptide: A prototype construct for integrin-mediated gene delivery. Hum Gene Ther 1998;9:1037-1047.
27. Pan H, Zheng Q, Guo X. A novel synthetic peptide vector system for optimal gene delivery to bone marrow stromal cells. J Pept Sci 2007;13:154-163.
28. Pan H, Zheng Q, Guo X. Synthetic RGD-containing peptide K16GRGDSPC affected the adhesion, proliferation and osteogenic differentiation of rabbit bone marrow stromal cells on PLGA-[ASP-PEG]n scaffolds materials. Med J China 2006;86: 2766-2770.
29. Pan H, Hao S, Zheng Q, Li J, Zheng J, Hu Z, Yang S, Guo X, Yang Q. Bone induction by biomimetic PLGA copolymer loaded with a novel synthetic RADA16-P24 peptide in vivo. Mater Sci Eng C 2013;33:3336-3345.
30. Duan Z, Zheng Q, Guo X, Li C, Wu B, Wu W. Repair of rabbit femoral defects with a novel BMP2-derived oligopeptide P24. J Huazhong Univ Sci Technolog Med Sci 2008;28:426-430.
31. Rusu VM, Ng CH, Wilke M, Tiersch B, Fratzl P, Peter MG. Sizecontrolled synthesis of hydroxyapatite nanorods by chemical precipitation in the presence of organic modifiers. J Mater Sci Eng 2007;27:865-869.
32. Bai J, Açan B, Ghahary A, Ritchie B, Somayaji V, Uludag H. Poly(ethyleneimine)/arginine-glycine-aspartic acid conjugates prepared with N-succinimidyl 3-(2-pyridyldithio)propionate: An investigation of peptide coupling and conjugate stability. J Polym Sci Part A: Polym Chem 2004;42:6143-6156.
33. Pan H, Zheng Q, Guo X, Liu Y, Song Y. Study on the isolation and identification of rabbit autogenous bone marrow stromal cells and transient expression of exogenous transforming growth factor b1 gene mediated with RGD-containing peptide gene delivery system in vitro. J Med Postgrad 2006;19:508-512.
34. Nugiel DJ, Wood DJ, Sung KL. Quantification of adhesiveness of osteoblasts to titanium surfaces in vitro by the micropipette aspiration technique. Tissue Eng 1996;2:127-140.
35. Liu X, Won Y, Ma PX. Surface modification of interconnected porous scaffolds. J Biomed Mater Res Part A 2005;74:84-91.
36. Vasita R, Shanmugam IK, Katt DS. Improved biomaterials for tissue engineering applications: Surface modification of polymers. Curr Top Med Chem 2008;8:341-353.
37. Ko E, Yang K, Shin J, Cho SW. Polydopamine-assisted osteoinductive peptide immobilization of polymer scaffolds for enhanced bone regeneration by human adipose-derived stem cells. Biomacromolecules 2013;14:3202-3213.
38. Bae SE, Bhang SH, Kim BS, Park K. Self-assembled extracellular macromolecular matrices and their different osteogenic potential with preosteoblasts and rat bone marrow mesenchymal stromal cells. Biomacromolecules 2012;13:2811-2820.
39. Kim JL, Park SH, Jeong D, Nam JS, Kang YH. Osteogenic activity of silymarin through enhancement of alkaline phosphatase and osteocalcin in osteoblasts and tibia-fractured mice. Exp Biol Med (Maywood) 2012;237:417-428.
40. Huang C, Ogawa R. Effect of hydrostatic pressure on bone regeneration using human mesenchymal stem cells. Tissue Eng Part A 2012;18:2106-2113.
41. Zhang P, Wu H, Wu H, Lú Z, Deng C, Hong Z, Jing X, Chen X. RGDconjugated copolymer incorporated into composite of poly(lactideco- glycotide) and poly(L-lactide)-grafted nanohydroxyapatite for bone tissue engineering. Biomacromolecules 2011;12:2667-2680.
42. Mathews S, Bhonde R, Gupta PK, Totey S. Extracellular matrix protein mediated regulation of the osteoblast differentiation of bone marrow derived human mesenchymal stem cells. Differentiation 2012;84:185-192.
43. Chien CY, Liu TY, Kuo WH, Wang MJ, Tsai WB. Dopamineassisted immobilization of hydroxyapatite nanoparticles and RGD peptides to improve the osteoconductivity of titanium. J Biomed Mater Res Part A 2013;101:740-747.