Idiopathic recurrent pericarditis as an immune-mediated disease: Current insights into pathogenesis and emerging treatment options

Expert Review of Clinical Immunology

Volumn 10, Issue 11, 2014, Pages 1487-1492

  Imazio, Massimo ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

pathogenesis; recurrent pericarditis; therapy

Indexed keywords

ACETYLSALICYLIC ACID; AZATHIOPRINE; BIOLOGICAL PRODUCT; C REACTIVE PROTEIN; COLCHICINE; CORTICOSTEROID; HLA A2 ANTIGEN; IBUPROFEN; IMMUNOGLOBULIN; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISONE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; ANTIRHEUMATIC AGENT; IMMUNOLOGIC FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUBULIN MODULATOR;

CONSTRICTIVE PERICARDITIS; DRUG TREATMENT FAILURE; IDIOPATHIC DISEASE; IDIOPATHIC RECURRENT PERICARDITIS; PATHOGENESIS; PERICARDITIS; PROGNOSIS; RECOMMENDED DRUG DOSE; RECURRENT DISEASE; RECURRENT INFECTION; REVIEW; T LYMPHOCYTE; DRUG COMBINATION; HUMAN; IMMUNOLOGY; PERICARDITIS, CONSTRICTIVE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIRHEUMATIC AGENTS; ASPIRIN; COLCHICINE; DRUG THERAPY, COMBINATION; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; PERICARDITIS, CONSTRICTIVE; RECURRENCE; TUBULIN MODULATORS;

EID: 84911483814     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/1744666X.2014.965150     Document Type: Review

References (50)

1. Spodick DH. The pericardium: a comprehensive textbook. Marcel Dekker; New York, NY, USA: 1997
2. Kabbani SS, LeWinter MM. Pericardial Diseases. Curr Treat Options Cardiovasc Med 2002;4(6):487-95
3. Imazio M, Bobbio M, Cecchi E, et al. Colchicine in addition to conventional therapy for acute pericarditis: results of the COlchicine for acute PEricarditis (COPE) trial. Circulation 2005;112(13):2012-16
4. Imazio M, Brucato A, Cemin R, et al. A randomized trial of colchicine for acute pericarditis. N Engl J Med 2013;369(16): 1522-8
5. Imazio M, Bobbio M, Cecchi E, et al. Colchicine as first-choice therapy for recurrent pericarditis:results of the CORE (COlchicine for REcurrent pericarditis) trial. Arch Intern Med 2005;165(17):1987-91
6. Imazio M, Brucato A, Cemin R, et al. Colchicine for recurrent pericarditis (CORP): a randomized trial. Ann Intern Med 2011;155(7):409-14
7. Imazio M, Belli R, Brucato A, et al. Efficacy and safety of colchicine for treatment of multiple recurrences of pericarditis (CORP-2): a multicentre, double-blind, placebo-controlled, randomised trial. Lancet 2014;383(9936): 2232-7
8. Maisch B, Seferović PM, Ristić AD, et al. Task force on the diagnosis and management of pericardial diseases of the European Society of Cardiology. Guidelines on the diagnosis and management of pericardial diseases executive summary; The Task force on the diagnosis and management of pericardial diseases of the European society of cardiology. Eur Heart J 2004;25(7):587-610
9. Sagristá Sauleda J, Almenar Bonet L, Angel Ferrer J, et al. [The clinical practice guidelines of the Sociedad Espanõla de Cardiologá on pericardial pathology]. Rev Esp Cardiol 2000;53(3):394-412
10. Montera MW, Mesquita ET, Colafranceschi AS, et al. I Brazilian guidelines on myocarditis and pericarditis. Arq Bras Cardiol 2013;100(4 Suppl 1):1-36
11. Imazio M. Contemporary management of pericardial diseases. Curr Opin Cardiol 2012;27(3):308-17
12. Ntsekhe M, Mayosi BM. Tuberculous pericarditis with and without HIV. Heart Fail Rev 2013;18(3):367-73
13. Imazio M, Brucato A, Derosa FG, et al. Aetiological diagnosis in acute and recurrent pericarditis: when and how. J Cardiovasc Med (Hagerstown) 2009;10(3):217-30
14. Gaspari S, Marsili M, Imazio M, et al. New insights in the pathogenesis and therapy of idiopathic recurrent pericarditis in children. Clin Exp Rheumatol 2013;31(5):788-94
15. Imazio M, Brucato A, Doria A, et al. Antinuclear antibodies in recurrent idiopathic pericarditis: prevalence and clinical significance. Int J Cardiol 2009; 136(3):289-93
16. Caforio AL, Brucato A, Doria A, et al. Anti-heart and anti-intercalated disk autoantibodies: evidence for autoimmunity in idiopathic recurrent acute pericarditis. Heart 2010;96(10):779-84
17. Brucato A, Maestroni S, Cumetti D, et al. Recurrent pericarditis: infectious or autoimmune Autoimmun Rev 2008;8(1): 44-7
18. Cantarini L, Imazio M, Brucato A, et al. Innate versus acquired immune response in the pathogenesis of recurrent idiopathic pericarditis. Autoimmun Rev 2010;9(6): 436-40
19. Imazio M. Pericardial involvement in systemic inflammatory diseases. Heart 2011; 97(22):1882-92
20. Cantarini L, Imazio M, Brizi MG, et al. Role of autoimmunity and autoinflammation in the pathogenesis of idiopathic recurrent pericarditis. Clin Rev Allergy Immunol 2013;44(1):6-13
21. Okutur K, Seber S, Oztekin E, et al. Recurrent pericarditis as the initial manifestation of Familial Mediterranean fever. Med Sci Monit 2008;14(12): CS139-41
22. Cantarini L, Lucherini OM, Cimaz R, et al. Idiopathic recurrent pericarditis refractory to colchicine treatment can reveal tumor necrosis factor receptor-associated periodic syndrome. Int J Immunopathol Pharmacol 2009;22(4):1051-8
23. Cantarini L, Lucherini OM, Brucato A, et al. Clues to detect tumor necrosis factor receptor-associated periodic syndrome (TRAPS) among patients with idiopathic recurrent acute pericarditis: results of a multicentre study. Clin Res Cardiol 2012; 101(7):525-31
24. Brucato A, Shinar Y, Brambilla G, et al. Idiopathic recurrent acute pericarditis: familial Mediterranean fever mutations and disease evolution in a large cohort of Caucasian patients. Lupus 2005;14(9):670-4
25. Maestroni S, Di Corato PR, Cumetti D, et al. Recurrent pericarditis: autoimmune or autoinflammatory Autoimmun Rev 2012; 12(1):60-5
26. Imazio M, Brucato A, Cumetti D, et al. Corticosteroids for recurrent pericarditis: high versus low doses: a nonrandomized observation. Circulation 2008;118(6): 667-71
27. Imazio M, Brucato A, Trinchero R, et al. Corticosteroid therapy for pericarditis: a double-edged sword. Nat Clin Pract Cardiovasc Med 2008;5(3):118-19
28. Imazio M, Brucato A, Maestroni S, et al. Prevalence of C-reactive protein elevation and time course of normalization in acute pericarditis: implications for the diagnosis, therapy, and prognosis of pericarditis. Circulation 2011;123(10):1092-7.
29. Vasileiou P, Tsioufis C, Lazaros G, et al. Interleukin-8 as a predictor of acute idiopathic pericarditis recurrences. A pilot study. Int J Cardiol 2014;172(3):e463-4
30. Cantarini L, Brucato A, Simonini G, et al. Leptin, adiponectin, resistin, visfatin serum levels and idiopathic recurrent pericarditis: biomarkers of disease activity A preliminary report. Clin Exp Rheumatol 2013;31(2): 207-12
31. Imazio M, Brucato A, Trinchero R, et al. Individualized therapy for pericarditis. Expert Rev Cardiovasc Ther 2009;7(8): 965-75
32. Lazaros G, Karavidas A, Spyropoulou M, et al. The role of the immunogenetic background in the development and recurrence of acute idiopathic pericarditis. Cardiology 2011;118(1):55-62
33. Cantarini L, Lucherini OM, Baldari CT, et al. Familial clustering of recurrent pericarditis may disclose tumour necrosis factor receptor-associated periodic syndrome. Clin Exp Rheumatol 2010;28(3):405-7
34. Imazio M, Brucato A, Mayosi BM, et al. Medical therapy of pericardial diseases: part I: idiopathic and infectious pericarditis. J Cardiovasc Med (Hagerstown) 2010;11(10): 712-22
35. Imazio M, Brucato A, Belli R, et al. Colchicine for the prevention of pericarditis: what we know and what we do not know in 2014-systematic review and meta-analysis. J Cardiovasc Med (Hagerstown) 2014. [Epub ahead of print]
36. Imazio M. Treatment of recurrent pericarditis. Rev Esp Cardiol (Engl Ed) 2014;67(5):345-8
37. Imazio M, Adler Y. Treatment with aspirin, NSAID, corticosteroids, and colchicine in acute and recurrent pericarditis. Heart Fail Rev 2013;18(3):355-60
38. Tona F, Bellotto F, Laveder F, et al. Efficacy of high-dose intravenous immunoglobulins in two patients with idiopathic recurrent pericarditis refractory to previous immunosuppressive treatment. Ital Heart J 2003;4(1):64-8
39. Peterlana D, Puccetti A, Simeoni S, et al. Efficacy of intravenous immunoglobulin in chronic idiopathic pericarditis: report of four cases. Clin Rheumatol 2005;24(1): 18-21
40. Moretti M, Buiatti A, Merlo M, et al. Usefulness of high-dose intravenous human immunoglobulins treatment for refractory recurrent pericarditis. Am J Cardiol 2013; 112(9):1493-8
41. Nieto González JC, Monteagudo Saez I, López-Longo FJ, et al. Idiopathic recurrent pericarditis treated successfully with tumour necrosis factor alpha blocking agents (anti-TNF-a). Clin Exp Rheumatol 2013;31(5): 776-8
42. Finetti M, Insalaco A, Cantarini L, et al. Long-term efficacy of interleukin-1 receptor antagonist (anakinra) in corticosteroid-dependent and colchicine-resistant recurrent pericarditis. J Pediatr 2014;164(6):1425-31
43. Camacho-Lovillo M, Méndez-Santos A. Successful treatment of idiopathic recurrent pericarditis with interleukin-1 receptor antagonist (Anakinra). Pediatr Cardiol 2013; 34(5):1293-4
44. Scardapane A, Brucato A, Chiarelli F, Breda L. Efficacy of an interleukin-1b receptor antagonist (anakinra) in idiopathic recurrent pericarditis. Pediatr Cardiol 2013; 34(8):1989-91
45. Vassilopoulos D, Lazaros G, Tsioufis C, et al. Successful treatment of adult patients with idiopathic recurrent pericarditis with an interleukin-1 receptor antagonist (anakinra). Int J Cardiol 2012;160(1):66-8
46. Lazaros G, Vasileiou P, Koutsianas C, et al. Anakinra for the management of resistant idiopathic recurrent pericarditis. Initial experience in 10 adult cases. Ann Rheum Dis 2014. [Epub ahead of print]
47. Imazio M, Brucato A, Adler Y, et al. Prognosis of idiopathic recurrent pericarditis as determined from previously published reports. Am J Cardiol 2007;100(6):1026-8
48. Imazio M, Demichelis B, Parrini I, et al. Recurrent pain without objective evidence of disease in patients with previous idiopathic or viral acute pericarditis. Am J Cardiol 2004;94(7):973-5
49. Brucato A, Brambilla G, Moreo A, et al. Long-term outcomes in difficult-to-treat patients with recurrent pericarditis. Am J Cardiol 2006;98(2):267-71
50. Imazio M, Brucato A, Maestroni S, et al. Risk of constrictive pericarditis after acute pericarditis. Circulation 2011;124(11): 1270-5