메뉴 건너뛰기




Volumn 12, Issue 11, 2014, Pages 1357-1369

Prognostic markers of meningococcal disease in children: Recent advances and future challenges

Author keywords

children; marker; meningococcal; prognosis; score; sepsis; severity

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CD16 ANTIGEN; CHOLESTEROL; COMPLEMENT COMPONENT C3; CORTICOTROPIN; FATTY ACID BINDING PROTEIN 2; FC RECEPTOR IIA; HYDROCORTISONE; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 6; INTERLEUKIN 8; LACTIC ACID; LIPOPOLYSACCHARIDE; LIPOPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROCALCITONIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

EID: 84911470875     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/14787210.2014.966079     Document Type: Review
Times cited : (11)

References (66)
  • 1
    • 0029825302 scopus 로고    scopus 로고
    • Pathophysiology, treatment and outcome of meningococcemia: A review and recent experience
    • Kirsch EA, Barton RP, Kitchen L, Giroir BP. Pathophysiology, treatment and outcome of meningococcemia: a review and recent experience. Pediatr Infect Dis J 1996; 15(11):967-79
    • (1996) Pediatr Infect Dis J , vol.15 , Issue.11 , pp. 967-979
    • Kirsch, E.A.1    Barton, R.P.2    Kitchen, L.3    Giroir, B.P.4
  • 3
  • 4
    • 33847098687 scopus 로고    scopus 로고
    • Meningococcemia: Epidemiology pathophysiology and management
    • Milonovich LM. Meningococcemia: epidemiology, Pathophysiology, and Management. J Pediatr Health Care 2007; 21(2):75-80
    • (2007) J Pediatr Health Care , vol.21 , Issue.2 , pp. 75-80
    • Milonovich, L.M.1
  • 5
    • 13844271447 scopus 로고    scopus 로고
    • The future of meningococcal vaccines
    • Healy CM, Baker CJ. The future of meningococcal vaccines. Pediatr Infect Dis J 2005;24(2):175-6
    • (2005) Pediatr Infect Dis J , vol.24 , Issue.2 , pp. 175-176
    • Healy, C.M.1    Baker, C.J.2
  • 7
    • 67349267346 scopus 로고    scopus 로고
    • Review: Global epidemiology of meningococcal disease
    • Harrison LH, Trotter CL, Ramsay ME. Review: global epidemiology of meningococcal disease. Vaccine 2009; 27(Suppl 2):B51-63
    • (2009) Vaccine , vol.27 , pp. B51-63
    • Harrison, L.H.1    Trotter, C.L.2    Ramsay, M.E.3
  • 9
    • 9644267080 scopus 로고    scopus 로고
    • Meningococcal sepsis in pediatrics. Parameters associated with poor outcome
    • Blanco-Quirós A, Casado Flores J, Nieto Moro M, et al. Meningococcal sepsis in pediatrics. Parameters associated with poor outcome. An Pediatr 2004;61(4): 305-13
    • (2004) An Pediatr , vol.61 , Issue.4 , pp. 305-313
    • Blanco-Quirós, A.1    Casado Flores, J.2    Nieto Moro, M.3
  • 10
    • 29244463340 scopus 로고    scopus 로고
    • Prognostic utility of the semi-quantitative procalcitonin test, neutrophil count and C-reactive protein in meningococcal infection in children
    • Casado-Flores J, Blanco-Quirós A, Nieto M, et al. Prognostic utility of the semi-quantitative procalcitonin test, neutrophil count and C-reactive protein in meningococcal infection in children. Eur J Pediatr 2006;165(1):26-9
    • (2006) Eur J Pediatr , vol.165 , Issue.1 , pp. 26-29
    • Casado-Flores, J.1    Blanco-Quirós, A.2    Nieto, M.3
  • 11
    • 0033862536 scopus 로고    scopus 로고
    • Procalcitonin and cytokine levels: Relationship to organ failure and mortality in pediatric septic shock
    • Hatherill M, Tibby SM, Turner C, et al. Procalcitonin and cytokine levels: relationship to organ failure and mortality in pediatric septic shock. Crit Care Med 2000;28(7):2591-4
    • (2000) Crit Care Med , vol.28 , Issue.7 , pp. 2591-2594
    • Hatherill, M.1    Tibby, S.M.2    Turner, C.3
  • 12
    • 12244251431 scopus 로고    scopus 로고
    • Prognostic value of procalcitonin in children with meningococcal sepsis
    • Carrol ED, Newland P, Thomson APJ, Hart CA. Prognostic value of procalcitonin in children with meningococcal sepsis. Crit Care Med 2005;33(1):224-5
    • (2005) Crit Care Med , vol.33 , Issue.1 , pp. 224-225
    • Carrol, E.D.1    Newland, P.2    Thomson, A.P.J.3    Hart, C.A.4
  • 13
    • 0027283534 scopus 로고
    • Variation in serum C-reactive protein across the clinical spectrum of meningococcal disease
    • Marzouk O, Bestwick K, Thomson APJ, et al. Variation in serum C-reactive protein across the clinical spectrum of meningococcal disease. Acta Paediatr 1993; 82(9):729-33
    • (1993) Acta Paediatr , vol.82 , Issue.9 , pp. 729-733
    • Marzouk, O.1    Bestwick, K.2    Thomson, A.P.J.3
  • 14
    • 0032830751 scopus 로고    scopus 로고
    • Comparison of procalcitonin with C-reactive protein, interleukin 6 and interferon-alpha for differentiation of bacterial vs viral infections
    • Gendrel D, Moulin F, Lorrot M, et al. Comparison of procalcitonin with C-reactive protein, interleukin 6 and interferon-alpha for differentiation of bacterial vs. viral infections. Pediatr Infect Dis J 1999;18(10):875-81
    • (1999) Pediatr Infect Dis J , vol.18 , Issue.10 , pp. 875-881
    • Gendrel, D.1    Moulin, F.2    Lorrot, M.3
  • 15
    • 0036906053 scopus 로고    scopus 로고
    • Procalcitonin as a prognostic marker in meningococcal disease
    • Van der Kaay DCM, De Kleijn ED, De Rijke YB, et al. Procalcitonin as a prognostic marker in meningococcal disease. Intensive Care Med 2002;28(11):1606-12
    • (2002) Intensive Care Med , vol.28 , Issue.11 , pp. 1606-1612
    • Van Der Kaay, D.C.M.1    De Kleijn, E.D.2    De Rijke, Y.B.3
  • 16
    • 0030769222 scopus 로고    scopus 로고
    • Meningococcal septic shock in children: Clinical and laboratory features, outcome, and development of a prognostic score
    • De Groot R, Kornelisse RF, Hazelzet JA, et al. Meningococcal septic shock in children: clinical and laboratory features, outcome, and development of a prognostic score. Clin Infect Dis 1997;25(3):640-6
    • (1997) Clin Infect Dis , vol.25 , Issue.3 , pp. 640-646
    • De Groot, R.1    Kornelisse, R.F.2    Hazelzet, J.A.3
  • 17
    • 0034837241 scopus 로고    scopus 로고
    • The child with a non-blanching rash: How likely is meningococcal disease?
    • Wells LC, Smith JC, Collier J, et al. The child with a non-blanching rash: how likely is meningococcal disease? Arch Dis Child 2001;85(3):218-22
    • (2001) Arch Dis Child , vol.85 , Issue.3 , pp. 218-222
    • Wells, L.C.1    Smith, J.C.2    Collier, J.3
  • 18
    • 10044271056 scopus 로고    scopus 로고
    • The value of leukopenia during the first hour of admission as a prognostic marker in meningococcal infection
    • Donoso FA, León B J, Rojas AG, et al. The value of leukopenia during the first hour of admission as a prognostic marker in meningococcal infection. Rev Chil Pediatr 2004;75(5):441-7
    • (2004) Rev Chil Pediatr , vol.75 , Issue.5 , pp. 441-447
    • Donoso, F.A.1    León, B.J.2    Rojas, A.G.3
  • 19
    • 84891825517 scopus 로고    scopus 로고
    • Altered Neutrophil Counts at Diagnosis of Invasive Meningococcal Infection in Children
    • Demissie DE, Kaplan SL, Romero JR, et al. Altered Neutrophil Counts at Diagnosis of Invasive Meningococcal Infection in Children. Pediatr Infect Dis J 2013;32(10): 1070-2
    • (2013) Pediatr Infect Dis J , vol.32 , Issue.10 , pp. 1070-1072
    • Demissie, D.E.1    Kaplan, S.L.2    Romero, J.R.3
  • 20
    • 0025165017 scopus 로고
    • Plasminogen activator inhibitor 1 and 2, alpha-2-antiplasmin, plasminogen, and endotoxin levels in systemic meningococcal disease
    • Brandtzaeg P, Joo GB, Brusletto B, Kierulf P. Plasminogen activator inhibitor 1 and 2, alpha-2-antiplasmin, plasminogen, and endotoxin levels in systemic meningococcal disease. Thromb Res 1990; 57(2):271-8
    • (1990) Thromb Res , vol.57 , Issue.2 , pp. 271-278
    • Brandtzaeg, P.1    Joo, G.B.2    Brusletto, B.3    Kierulf, P.4
  • 21
    • 0033554250 scopus 로고    scopus 로고
    • 4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease
    • Hermans PW, Hazelzet JA, De Groot R, et al. 4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease. Lancet 1999;354(9178):556-60
    • (1999) Lancet , vol.354 , Issue.9178 , pp. 556-560
    • Hermans, P.W.1    Hazelzet, J.A.2    De Groot, R.3
  • 22
    • 0024419991 scopus 로고
    • The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease
    • Brandtzaeg P, Sandset PM, Joo GB, et al. The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease. Thromb Res 1989;55(4):459-70
    • (1989) Thromb Res , vol.55 , Issue.4 , pp. 459-470
    • Brandtzaeg, P.1    Sandset, P.M.2    Joo, G.B.3
  • 23
    • 0028855106 scopus 로고
    • Coagulation activation and tissue necrosis in meningococcal septic shock: Severely reduced protein C levels predict a high mortality
    • Fijnvandraat K, Derkx B, Peters M, et al. Coagulation activation and tissue necrosis in meningococcal septic shock: severely reduced protein C levels predict a high mortality. Thromb Haemost 1995;73(1): 15-20
    • (1995) Thromb Haemost , vol.73 , Issue.1 , pp. 15-20
    • Fijnvandraat, K.1    Derkx, B.2    Peters, M.3
  • 24
    • 38549157626 scopus 로고    scopus 로고
    • Thrombin activatable fibrinolysis inhibitor is associated with severity and outcome of severe meningococcal infection in children
    • Emonts M, De Bruijne EL, Guimarães AH, et al. Thrombin activatable fibrinolysis inhibitor is associated with severity and outcome of severe meningococcal infection in children. J Thromb Haemost 2008;6(2): 268-76
    • (2008) J Thromb Haemost , vol.6 , Issue.2 , pp. 268-276
    • Emonts, M.1    De Bruijne, E.L.2    Guimarães, A.H.3
  • 25
    • 0033957876 scopus 로고    scopus 로고
    • Update on meningococcal disease with emphasis on pathogenesis and clinical management
    • Van Deuren M, Van Der Meer JW, Brandtzaeg P. Update on meningococcal disease with emphasis on pathogenesis and clinical management. Clin Microbiol Rev 2000;13(1):144-66
    • (2000) Clin Microbiol Rev , vol.13 , Issue.1 , pp. 144-166
    • Van Deuren, M.1    Van Der Meer, J.W.2    Brandtzaeg, P.3
  • 26
    • 0036223608 scopus 로고    scopus 로고
    • Low serum cortisol in combination with high adrenocorticotrophic hormone concentrations are associated with poor outcome in children with severe meningococcal disease
    • Kleijn ED, Joosten KF, Rijn BV, et al. Low serum cortisol in combination with high adrenocorticotrophic hormone concentrations are associated with poor outcome in children with severe meningococcal disease. Pediatr Infect Dis J 2002;21(4):330-6
    • (2002) Pediatr Infect Dis J , vol.21 , Issue.4 , pp. 330-336
    • Kleijn, E.D.1    Joosten, K.F.2    Rijn, B.V.3
  • 27
    • 0035892933 scopus 로고    scopus 로고
    • Adrenocorticotropic hormone and cortisol levels in relation to inflammatory response and disease severity in children with meningococcal disease
    • Woensel JB, Biezeveld MH, Alders AM, et al. Adrenocorticotropic hormone and cortisol levels in relation to inflammatory response and disease severity in children with meningococcal disease. J Infect Dis 2001;184(12):1532-7
    • (2001) J Infect Dis , vol.184 , Issue.12 , pp. 1532-1537
    • Woensel, J.B.1    Biezeveld, M.H.2    Alders, A.M.3
  • 28
    • 0024576318 scopus 로고
    • Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease
    • Brandtzaeg P, Kierulf P, Gaustad P, et al. Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease. J Infect Dis 1989; 159(2):195-204
    • (1989) J Infect Dis , vol.159 , Issue.2 , pp. 195-204
    • Brandtzaeg, P.1    Kierulf, P.2    Gaustad, P.3
  • 29
    • 0027773129 scopus 로고
    • The protective effect of serum lipoproteins against bacterial lipopolysaccharide
    • Read TE, Harris HW, Grunfeld C, et al. The protective effect of serum lipoproteins against bacterial lipopolysaccharide. Eur Heart J 1993;14(Suppl K):125-9
    • (1993) Eur Heart J , vol.14 , pp. 125-129
    • Read, T.E.1    Harris, H.W.2    Grunfeld, C.3
  • 31
    • 22144490879 scopus 로고    scopus 로고
    • Serum lipids and disease severity in children with severe meningococcal sepsis
    • Vermont CL, den Brinker M, Kâkeci N, et al. Serum lipids and disease severity in children with severe meningococcal sepsis. Crit Care Med 2005;33(7):1610-15
    • (2005) Crit Care Med , vol.33 , Issue.7 , pp. 1610-1615
    • Vermont, C.L.1    Den Brinker, M.2    Kâkeci, N.3
  • 32
    • 33845495289 scopus 로고    scopus 로고
    • CC and CXC chemokine levels in children with meningococcal sepsis accurately predict mortality and disease severity
    • Vermont CL, Hazelzet JA, Kleijn ED, et al. CC and CXC chemokine levels in children with meningococcal sepsis accurately predict mortality and disease severity. Crit Care 2006;10(1):R33-3
    • (2006) Crit Care , vol.10 , Issue.1 , pp. R33-R43
    • Vermont, C.L.1    Hazelzet, J.A.2    Kleijn, E.D.3
  • 33
    • 26444549974 scopus 로고    scopus 로고
    • A predominantly anti-inflammatory cytokine profile is associated with disease severity in meningococcal sepsis
    • Carrol ED, Thomson AP, Jones AP, et al. A predominantly anti-inflammatory cytokine profile is associated with disease severity in meningococcal sepsis. Intensive Care Med 2005;31(10):1415-19
    • (2005) Intensive Care Med , vol.31 , Issue.10 , pp. 1415-1419
    • Carrol, E.D.1    Thomson, A.P.2    Jones, A.P.3
  • 34
    • 70349695923 scopus 로고    scopus 로고
    • Influence of innate cytokine production capacity on clinical manifestation and severity of pediatric meningococcal disease
    • Sprong T, Van Der Ven-Jongekrijg J, Van Der Meer JW, et al. Influence of innate cytokine production capacity on clinical manifestation and severity of pediatric meningococcal disease. Crit Care Med 2009;37(10):2812-18
    • (2009) Crit Care Med , vol.37 , Issue.10 , pp. 2812-2818
    • Sprong, T.1    Van Der Ven-Jongekrijg, J.2    Van Der Meer, J.W.3
  • 35
    • 0031048720 scopus 로고    scopus 로고
    • Human intestinal fatty acid binding protein: Report of an assay with studies in normal volunteers and intestinal ischemia
    • Lieberman JM, Sacchettini J, Marks C, Marks WH. Human intestinal fatty acid binding protein: report of an assay with studies in normal volunteers and intestinal ischemia. Surgery 1997;121(3):335-42
    • (1997) Surgery , vol.121 , Issue.3 , pp. 335-342
    • Lieberman, J.M.1    Sacchettini, J.2    Marks, C.3    Marks, W.H.4
  • 36
    • 11844291275 scopus 로고    scopus 로고
    • Fatty acid-binding proteins as plasma markers of tissue injury
    • Pelsers MM, Glatz JF, Hermens WT. Fatty acid-binding proteins as plasma markers of tissue injury. Clin Chim Acta 2005; 352(1-2):15-35
    • (2005) Clin Chim Acta , vol.352 , Issue.1-2 , pp. 15-35
    • Pelsers, M.M.1    Glatz, J.F.2    Hermens, W.T.3
  • 37
    • 37349018992 scopus 로고    scopus 로고
    • Evidence for intestinal and liver epithelial cell injury in the early phase of sepsis
    • Derikx JP, Poeze M, Van Bijnen AA, et al. Evidence for intestinal and liver epithelial cell injury in the early phase of sepsis. Shock 2007;28(5):544-8
    • (2007) Shock , vol.28 , Issue.5 , pp. 544-548
    • Derikx, J.P.1    Poeze, M.2    Van Bijnen, A.A.3
  • 38
    • 74049084059 scopus 로고    scopus 로고
    • Gut mucosal cell damage in meningococcal sepsis in children: Relation with clinical outcome
    • Derikx JP, Bijker EM, Vos GD, et al. Gut mucosal cell damage in meningococcal sepsis in children: relation with clinical outcome. Crit Care Med 2010;38(1):133-7
    • (2010) Crit Care Med , vol.38 , Issue.1 , pp. 133-137
    • Derikx, J.P.1    Bijker, E.M.2    Vos, G.D.3
  • 40
    • 77949545788 scopus 로고    scopus 로고
    • Host genetics and outcome in meningococcal disease: A systematic review and meta-analysis
    • Brouwer MC, van de Beek D, Read RC. Host genetics and outcome in meningococcal disease: a systematic review and meta-analysis. Lancet Infect Dis 2010; 10(4):262-74.
    • (2010) Lancet Infect Dis , vol.10 , Issue.4 , pp. 262-274
    • Brouwer, M.C.1    Van De Beek, D.2    Read, R.C.3
  • 41
    • 23044459987 scopus 로고    scopus 로고
    • 4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene in children with systemic meningococcaemia
    • Geishofer G, Binder A, Müller M, et al. 4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene in children with systemic meningococcaemia. Eur J Pediatr 2005;164(8):486-90
    • (2005) Eur J Pediatr , vol.164 , Issue.8 , pp. 486-490
    • Geishofer, G.1    Binder, A.2    Müller, M.3
  • 42
    • 34548839906 scopus 로고    scopus 로고
    • 4G4G genotype of the plasminogen activator inhibitor-1 promoter polymorphism associates with disseminated intravascular coagulation in children with systemic meningococcemia
    • Binder A, Müller M, Zenz W, et al. 4G4G genotype of the plasminogen activator inhibitor-1 promoter polymorphism associates with disseminated intravascular coagulation in children with systemic meningococcemia. J Thromb Haemost 2007;5(10):2049-54
    • (2007) J Thromb Haemost , vol.5 , Issue.10 , pp. 2049-2054
    • Binder, A.1    Müller, M.2    Zenz, W.3
  • 43
    • 0345860914 scopus 로고    scopus 로고
    • Role of functional plasminogenactivator-inhibitor-1 4G/5G promoter polymorphism in susceptibility, severity, and outcome of meningococcal disease in Caucasian children
    • Haralambous E, Hibberd ML, Levin M, et al. Role of functional plasminogenactivator-inhibitor-1 4G/5G promoter polymorphism in susceptibility, severity, and outcome of meningococcal disease in Caucasian children. Crit Care Med 2003; 31(12):2788-93
    • (2003) Crit Care Med , vol.31 , Issue.12 , pp. 2788-2793
    • Haralambous, E.1    Hibberd, M.L.2    Levin, M.3
  • 44
    • 27744559524 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor type 1 gene polymorphism and sepsis
    • Hermans PW, Hazelzet JA. Plasminogen activator inhibitor type 1 gene polymorphism and sepsis. Clin Infect Dis 2005;41:S453-8
    • (2005) Clin Infect Dis , vol.41 , pp. S453-S458
    • Hermans, P.W.1    Hazelzet, J.A.2
  • 45
    • 0035826096 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Ely EW, Vincent JL, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344(10):699-709
    • (2001) N Engl J Med , vol.344 , Issue.10 , pp. 699-709
    • Bernard, G.R.1    Ely, E.W.2    Vincent, J.L.3
  • 46
    • 67349221334 scopus 로고    scopus 로고
    • Fulminant sepsis/meningitis due to haemophilus influenzae in a protein C-deficient heterozygote treated with activated protein C therapy
    • Ishimura M, Saito M, Ohga S, et al. Fulminant sepsis/meningitis due to haemophilus influenzae in a protein C-deficient heterozygote treated with activated protein C therapy. Eur J Pediatr 2009;168(6):673-7
    • (2009) Eur J Pediatr , vol.168 , Issue.6 , pp. 673-677
    • Ishimura, M.1    Saito, M.2    Ohga, S.3
  • 47
    • 4544237062 scopus 로고    scopus 로고
    • Relevance of genetically determined host factors to the prognosis of meningococcal disease
    • Domingo P, Baraldès MA, Barquet N, et al. Relevance of genetically determined host factors to the prognosis of meningococcal disease. Eur J Clin Microbiol Infect Dis 2004;23(8):634-7
    • (2004) Eur J Clin Microbiol Infect Dis , vol.23 , Issue.8 , pp. 634-637
    • Domingo, P.1    Baraldès, M.A.2    Barquet, N.3
  • 48
    • 0030744780 scopus 로고    scopus 로고
    • Prognostic factors in meningococcal disease. Development of a bedside predictive model and scoring system
    • Barcelona Meningococcal Disease Surveillance Group
    • Barquet N, Domingo P, Caylà JA, et al. Prognostic factors in meningococcal disease. Development of a bedside predictive model and scoring system. Barcelona Meningococcal Disease Surveillance Group. JAMA 1997;278(6):491-6
    • (1997) JAMA , vol.278 , Issue.6 , pp. 491-496
    • Barquet, N.1    Domingo, P.2    Caylà, J.A.3
  • 49
    • 59149086761 scopus 로고    scopus 로고
    • A toll-like receptor 4 variant is associated with fatal outcome in children with invasive meningococcal disease
    • Faber J, Henninger N, Zepp F, et al. A toll-like receptor 4 variant is associated with fatal outcome in children with invasive meningococcal disease. Acta Paediatr 2009; 98(3):548-52
    • (2009) Acta Paediatr , vol.98 , Issue.3 , pp. 548-552
    • Faber, J.1    Henninger, N.2    Zepp, F.3
  • 50
    • 84860792168 scopus 로고    scopus 로고
    • Toll-like receptor 9 polymorphisms are associated with severity variables in a cohort of meningococcal meningitis survivors
    • Sanders MS, Ouburg S, Morré SA, et al. Toll-like receptor 9 polymorphisms are associated with severity variables in a cohort of meningococcal meningitis survivors. BMC Infect Dis 2012;12:112
    • (2012) BMC Infect Dis , vol.12 , pp. 112
    • Sanders, M.S.1    Ouburg, S.2    Morré, S.A.3
  • 51
    • 84861477874 scopus 로고    scopus 로고
    • Polymorphisms in toll-like receptors 2 4 and 9 are highly associated with hearing loss in survivors of bacterial meningitis
    • van Well GT, Sanders MS, van Furth AM, et al. Polymorphisms in toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis. PLoS One 2012;7(5):e35837
    • (2012) PLoS One , vol.7 , Issue.5 , pp. e35837
    • Van Well, G.T.1    Sanders, M.S.2    Van Furth, A.M.3
  • 53
    • 0029848021 scopus 로고    scopus 로고
    • Heterozygous and homozygous factor H deficiency states in a Dutch family
    • Fijen CAP, Kuijper EJ, Van De Heuvel MM, et al. Heterozygous and homozygous factor H deficiency states in a Dutch family. Clin Exp Immunol 1996;105(3):511-16
    • (1996) Clin Exp Immunol , vol.105 , Issue.3 , pp. 511-516
    • Fijen, C.A.P.1    Kuijper, E.J.2    Van De Heuvel, M.M.3
  • 54
    • 0024803091 scopus 로고
    • Hereditary, complete deficiency of complement factor H associated with recurrent meningococcal disease
    • Nielsen HE, Christensen KC, Koch C, et al. Hereditary, complete deficiency of complement factor H associated with recurrent meningococcal disease. Scand J Immunol 1989;30(6):711-18
    • (1989) Scand J Immunol , vol.30 , Issue.6 , pp. 711-718
    • Nielsen, H.E.1    Christensen, K.C.2    Koch, C.3
  • 55
    • 33748109566 scopus 로고    scopus 로고
    • Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients
    • Haralambous E, Dolly SO, Hibberd ML, et al. Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients. Scand J Infect Dis 2006;38(9):764-71
    • (2006) Scand J Infect Dis , vol.38 , Issue.9 , pp. 764-771
    • Haralambous, E.1    Dolly, S.O.2    Hibberd, M.L.3
  • 57
    • 0034988822 scopus 로고    scopus 로고
    • Can generic scores (Pediatric Risk of Mortality and Pediatric Index of Mortality) replace specific scores in predicting the outcome of presumed meningococcal septic shock in children?
    • Leteurtre S, Leclerc F, Martinot A, et al. Can generic scores (Pediatric Risk of Mortality and Pediatric Index of Mortality) replace specific scores in predicting the outcome of presumed meningococcal septic shock in children? Crit Care Med 2001; 29(6):1239-46
    • (2001) Crit Care Med , vol.29 , Issue.6 , pp. 1239-1246
    • Leteurtre, S.1    Leclerc, F.2    Martinot, A.3
  • 58
    • 0034953366 scopus 로고    scopus 로고
    • Comparison of two different severity scores (Paediatric Risk of Mortality [PRISM] and the Glasgow Meningococcal Sepsis Prognostic Score [GMSPS]) in meningococcal disease: Preliminary analysis
    • Silva PS, Fonseca MC, Iglesias SB, et al. Comparison of two different severity scores (Paediatric Risk of Mortality [PRISM] and the Glasgow Meningococcal Sepsis Prognostic Score [GMSPS]) in meningococcal disease: preliminary analysis. Ann Trop Paediatr 2001;21(2):135-40
    • (2001) Ann Trop Paediatr , vol.21 , Issue.2 , pp. 135-140
    • Silva, P.S.1    Fonseca, M.C.2    Iglesias, S.B.3
  • 59
    • 0033839065 scopus 로고    scopus 로고
    • Comparison of the performance of two general and three specific scoring systems for meningococcal septic shock in children
    • Castellanos-Ortega A, Delgado-Rodr?guez M. Comparison of the performance of two general and three specific scoring systems for meningococcal septic shock in children. Crit Care Med 2000;28(8):2967-73
    • (2000) Crit Care Med , vol.28 , Issue.8 , pp. 2967-2973
    • Castellanos-Ortega A Delgado-Rodŕguez, M.1
  • 60
    • 0036392645 scopus 로고    scopus 로고
    • Prospective validation of the Glasgow Meningococcal Septicaemia Prognostic Score. Comparison with other scoring methods
    • Riordan FA, Marzouk O, Thomson AP, et al. Prospective validation of the Glasgow Meningococcal Septicaemia Prognostic Score. Comparison with other scoring methods. Eur J Pediatr 2002;161(10):531-7
    • (2002) Eur J Pediatr , vol.161 , Issue.10 , pp. 531-537
    • Riordan, F.A.1    Marzouk, O.2    Thomson, A.P.3
  • 61
    • 0025975615 scopus 로고
    • Validation of the Glasgow Meningococcal Septicemia Prognostic Score: A 10-year retrospective survey
    • Thomson AP, Sills JA, Hart CA. Validation of the Glasgow Meningococcal Septicemia Prognostic Score: a 10-year retrospective survey. Crit Care Med 1991;19(1):26-30
    • (1991) Crit Care Med , vol.19 , Issue.1 , pp. 26-30
    • Thomson, A.P.1    Sills, J.A.2    Hart, C.A.3
  • 62
    • 84911483099 scopus 로고    scopus 로고
    • Grupo de trabajo de la Gu?á de Práctica Cl?nica sobre el Manejo de la Enfermedad Meningocócica Invasiva Ministerio de Sanidad, Servicios Sociales e Igualdad. Instituto Aragonés de Ciencias de la Salud; Gu?ás de Práctica Cl?nica en el SNS: IACS N° 2011/01
    • Grupo de trabajo de la Gu?á de Práctica Cl?nica sobre el Manejo de la Enfermedad Meningocócica Invasiva. Gu?á de Práctica Cl?nica sobre el Manejo de la Enfermedad Meningocócica Invasiva. Ministerio de Sanidad, Servicios Sociales e Igualdad. Instituto Aragonés de Ciencias de la Salud; Gu?ás de Práctica Cl?nica en el SNS: IACS N° 2011/01. 2013.
    • (2013) Gu?á de Práctica Cl?nica Sobre El Manejo de la Enfermedad Meningocócica Invasiva
  • 63
    • 84878107523 scopus 로고    scopus 로고
    • A new scoring system derived from platelet count and base deficit at presentation predicts mortality in paediatric meningococcal sepsis
    • Alves AC, Wright VJ, Perumal K, et al. A new scoring system derived from platelet count and base deficit at presentation predicts mortality in paediatric meningococcal sepsis. Crit Care (London, England) 2013;17(2):R68-8
    • (2013) Crit Care (London, England) , vol.17 , Issue.2 , pp. R68-R78
    • Alves, A.C.1    Wright, V.J.2    Perumal, K.3
  • 64
    • 0011926516 scopus 로고    scopus 로고
    • Early severe neutropenia and thrombocytopenia identifies the highest risk cases of severe meningococcal disease
    • Peters MJ, Ross-Russell RI, White D, et al. Early severe neutropenia and thrombocytopenia identifies the highest risk cases of severe meningococcal disease. Pediatr Crit Care Med 2001;2(3):225-31
    • (2001) Pediatr Crit Care Med , vol.2 , Issue.3 , pp. 225-231
    • Peters, M.J.1    Ross-Russell, R.I.2    White, D.3
  • 65
    • 34447333440 scopus 로고    scopus 로고
    • The product of platelet and neutrophil counts (PN product) at presentation as a predictor of outcome in children with meningococcal disease
    • Silva PS, Iglesias SB, Nakakura CH, et al. The product of platelet and neutrophil counts (PN product) at presentation as a predictor of outcome in children with meningococcal disease. Ann Trop Paediatr 2007;27(1):25-30
    • (2007) Ann Trop Paediatr , vol.27 , Issue.1 , pp. 25-30
    • Silva, P.S.1    Iglesias, S.B.2    Nakakura, C.H.3
  • 66
    • 84911461282 scopus 로고    scopus 로고
    • Available from Eu
    • EUCLIDS. Available from: www.euclidsproject. Eu
    • EUCLIDS


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.