Rare infection of implantable cardioverter-defibrillator lead with Candida albicans: Case report and literature review

Therapeutic Advances in Cardiovascular Disease

Volumn 8, Issue 5, 2014, Pages 193-201

  Rivera, Nina Thakkar ^a   Bray, Natasha ^a   Wang, Hong ^a   Zelnick, Kenneth ^b   Vicuña, Ricardo ^b   Osman, Ahmed ^c  

^a BROWARD HEALTH MEDICAL CENTER   (United States)

^b Broward Health Medical Center   (United States)

^c Department of Cardiology Electrophysiology Broward Health Medical Center   (United States)

Author keywords

Candida albicans; endocarditis; implantable cardioverter defibrillator; pacemaker

Indexed keywords

ANTIFUNGAL AGENT; ECHINOCANDIN; FLUCONAZOLE; LIPOPEPTIDE; MICAFUNGIN; AMPHOTERICIN; CEFTRIAXONE; VANCOMYCIN;

CANDIDA ALBICANS; CANDIDIASIS; CASE REPORT; ECHOCARDIOGRAPHY; ENDOCARDITIS; FEMALE; HUMAN; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; PROSTHESIS-RELATED INFECTIONS; ADULT; CARDIAC EQUIPMENT; CARDIOPULMONARY BYPASS; CHILL; CHRONIC KIDNEY DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONGESTIVE HEART FAILURE; COUGHING; DEVICE REMOVAL; DIABETES MELLITUS; FEVER; FUNGUS BALL; HEART ARRHYTHMIA; HEART LEFT VENTRICLE EJECTION FRACTION; HEART VENTRICLE TACHYCARDIA; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR LEAD; INSULIN DEPENDENT DIABETES MELLITUS; LUNG LAVAGE; MEDICAL DEVICE COMPLICATION; MYCOSIS; RARE DISEASE; RECURRENT FEVER; REVIEW; SARCOIDOSIS; SINGLE CHAMBER PACEMAKER; STERNOTOMY; THORAX PAIN; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TRANSTHORACIC ECHOCARDIOGRAPHY;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; DEFIBRILLATORS, IMPLANTABLE; ECHINOCANDINS; ECHOCARDIOGRAPHY; ENDOCARDITIS; FEMALE; FLUCONAZOLE; HUMANS; LIPOPEPTIDES; MIDDLE AGED; PROSTHESIS-RELATED INFECTIONS;

EID: 84911421973     PISSN: 17539447     EISSN: 17539455     Source Type: Journal    
DOI: 10.1177/1753944714539406     Document Type: Review

References (62)

1. Arber N. Pras E. Copperman Y. Schapiro J. Meiner V. Lossos I. et al. (1994) Pacemaker endocarditis. Report of 44 cases and review of the literature. Medicine (Baltimore) 73: 299–305.
2. Athan E. Chu V. Tattevin P. Selton-Suty C. Jones P. Naber C. et al. (2012) Clinical characteristics and outcome of infective endocarditis involving implantable cardiac devices. JAMA 307: 1727–1735.
3. Baddour L. Bettmann M. Bolger A. Epstein A. Ferrieri P. Gerber M. et al. (2003) Nonvalvular cardiovascular device-related infections. Circulation 108: 2015–2031.
4. Baddour L. Epstein A. Erickson C. Knight B. Levison M. Lockhart P. et al. (2010) Update on cardiovascular implantable electronic device infections and their management: a scientific statement from the American Heart Association. Circulation 121: 458–477.
5. Bloom H. Heeke B. Leon A. Mera F. Delurgio D. Beshai J. et al. (2006) Renal insufficiency and the risk of infection from pacemaker or defibrillator surgery. Pacing Clin Electrophysiol 29: 142–145.
6. Bluhm G. Julander I. Levander-Lindgren M. Olin C. (1982) Septicaemia and endocarditis – uncommon but serious complications in connection with permanent cardiac pacing. Scand J Thorac Cardiovasc Surg 16: 65–70.
7. Bohm A. Banyai F. Preda I. Zamolyi K. (1996) The treatment of septicemia in pacemaker patients. Pacing Clin Electrophysiol 19: 1105–1111.
8. Bracke F. van Gelder L. Sreeram N. Meijer A. (2000) Exchange of pacing or defibrillator leads following laser sheath extraction of non-functional leads in patients with ipsilateral obstructed venous access. Heart 83: E12.
9. Brown L. Baddley J. Sanchez J. Bachmann L. (2001) Implantable cardioverter-defibrillator endocarditis secondary to Candida albicans. Am J Med Sci 322: 160–162.
10. Bryan C. Sutton J. Saunders D. Jr Longaker D. Smith C. (1978) Endocarditis related to transvenous pacemakers. syndromes and surgical implications. J Thorac Cardiovasc Surg 75: 758–762.
11. Cacoub P. Leprince P. Nataf P. Hausfater P. Dorent R. Wechsler B. et al. (1998) Pacemaker infective endocarditis. Am J Cardiol 82: 480–484.
12. Chua J. Wilkoff B. Lee I. Juratli N. Longworth D. Gordon S. (2000) Diagnosis and management of infections involving implantable electrophysiologic cardiac devices. Ann Intern Med 133: 604–608.
13. Darouiche R. (2004) Treatment of infections associated with surgical implants. N Engl J Med 350: 1422–1429.
14. Del Rio A. Anguera I. Miro J. Mont L. Fowler V. Jr Azqueta M. et al. (2003) Surgical treatment of pacemaker and defibrillator lead endocarditis: the impact of electrode lead extraction on outcome. Chest 124: 1451–1459.
15. D'enfert C. (2006) Biofilms and their role in the resistance of pathogenic Candida to antifungal agents. Curr Drug Targets 7: 465–470.
16. Dumont E. Camus C. Victor F. de Place C. Pavin D. Alonso C. et al. (2003) Suspected pacemaker or defibrillator transvenous lead infection. prospective assessment of a tee-guided therapeutic strategy. Eur Heart J 24: 1779–1787.
17. Durack D. Lukes A. Bright D. (1994) New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service. Am J Med 96: 200–209.
18. Duval X. Selton-Suty C. Alla F. Salvador-Mazenq M. Bernard Y. Weber M. et al. (2004) Endocarditis in patients with a permanent pacemaker: a 1-year epidemiological survey on infective endocarditis due to valvular and / or pacemaker infection. Clin Infect Dis 39: 68–74.
19. Eggimann P. Waldvogel F. (2000) Pacemaker and defibrillator infections. In: In: Ed. Waldvogel F. Bisno A. (eds), Infections Associated with Indwelling Medical Devices (pp. 247–265). Washington DC: American Society for Microbiology Press.
20. Ellis M. (1997) Fungal endocarditis. J Infect 35: 99–103.
21. Giamarellou H. (2002) Nosocomial cardiac infections. J Hosp Infect 50: 91–105.
22. Grunberg W. Al-Bataineh M. Weiss S. (2013) Candida albicans endocarditis with giant vegetation from an implantable cardioverter-defibrillator lead. Surg Infect (Larchmt) 14: 157–159.
23. Halawa A. Henry P. Sarubbi F. (2011) Candida endocarditis associated with cardiac rhythm management devices: review with current treatment guidelines. Mycoses 54: e168–e174.
24. Heimberger T. Duma R. (1989) Infections of prosthetic heart valves and cardiac pacemakers. Infect Dis Clin North Am 3: 221–245.
25. Hindupur S. Muslin A. (2005) Septic shock induced from an implantable cardioverter-defibrillator lead-associated Candida albicans vegetation. J Interv Card Electrophysiol 14: 55–59.
26. Ho I. Milan D. Mansour M. Mela T. Guy M. Ruskin J. et al. (2006) Fungal infection of implantable cardioverter-defibrillators: case series of five patients managed over 22 years. Heart Rhythm 3: 919–923.
27. Isotalo P. Chan K. Rubens F. Beanlands D. Auclair F. Veinot J. (2001) Prosthetic valve fungal endocarditis due to histoplasmosis. Can J Cardiol 17: 297–303.
28. Joly V. Belmatoug N. Leperre A. Robert J. Jault F. Carbon C. et al. (1997) Pacemaker endocarditis due to Candida albicans: case report and review. Clin Infect Dis 25: 1359–1362.
29. Karchmer A. Longworth D. (2002) Infections of intracardiac devices. Infect Dis Clin North Am 16: 477–505, xii.
30. Kennelly B.M. Piller L.W. (1974) Management of Infected Transvenous Permanent Pacemakers. Br Heart J 36: 1133–1140.
31. Klug D. Balde M. Pavin D. (2003) Prospective evaluation of pacemaker lead endocarditis: 6 months preliminary results. Eur Heart J 24: 28.
32. Klug D. Balde M. Pavin D. Hidden-Lucet F. Clementy J. Sadoul N. et al. (2007) Risk factors related to infections of implanted pacemakers and cardioverter-defibrillators: results of a large prospective study. Circulation 116: 1349–1355.
33. Klug D. Lacroix D. Savoye C. Goullard L. Grandmougin D. Hennequin J. et al. (1997) Systemic infection related to endocarditis on pacemaker leads: clinical presentation and management. Circulation 95: 2098–2107.
34. Klug D. Wallet F. Lacroix D. Marquie C. Kouakam C. Kacet S. et al. (2004) Local symptoms at the site of pacemaker implantation indicate latent systemic infection. Heart 90: 882–886.
35. Kojic E. Darouiche R. (2004) Candida infections of medical devices. Clin Microbiol Rev 17: 255–267.
36. Kurup A. Janardhan M. Seng T. (2000) Candida tropicalis pacemaker endocarditis. J Infect 41: 275–276.
37. Lai K. Fontecchio S. (1998) Infections associated with implantable cardioverter defibrillators placed transvenously and via thoracotomies: epidemiology, infection control, and management. Clin Infect Dis 27: 265–269.
38. Le K. Sohail M. Friedman P. Uslan D. Cha S. Hayes D. et al. (2011) Impact of timing of device removal on mortality in patients with cardiovascular implantable electronic device infections. Heart Rhythm 8: 1678–1685.
39. Lekkerkerker J. van Nieuwkoop C. Trines S. van der Bom J. Bernards A. van de Velde E. et al. (2009) Risk factors and time delay associated with cardiac device infections: Leiden Device Registry. Heart 95: 715–720.
40. Lewis A. Hayes D. Holmes D. Jr Vlietstra R. Pluth J. Osborn M. (1985) Update on infections involving permanent pacemakers. Characterization and management. J Thorac Cardiovasc Surg 89: 758–763.
41. Mansour K. Kauten J. Hatcher C. Jr (1985) Management of the infected pacemaker: explantation, sterilization, and reimplantation. Ann Thorac Surg 40: 617–619.
42. Massoure P. Reuter S. Lafitte S. Laborderie J. Bordachard P. Clementy J. et al. (2007) Pacemaker endocarditis: clinical features and management of 60 consecutive cases. Pacing Clin Electrophysiol 30: 12–19.
43. Mehta G. (1990) Aspergillus endocarditis after open heart surgery: an epidemiological investigation. J Hosp Infect 15: 245–253.
44. Meier-Ewert H. Gray M. John R. (2003) Endocardial pacemaker or defibrillator leads with infected vegetations: a single-center experience and consequences of transvenous extraction. Am Heart J 146: 339–344.
45. Nguyen K. Neese P. Kessler D. (2000) Successful laser-assisted percutaneous extraction of four pacemaker leads associated with large vegetations. Pacing Clin Electrophysiol 23: 1260–1262.
46. Pappas P. Kauffman C. Andes D. Benjamin D. Jr Calandra T. Edwards J. Jr et al. (2009) Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 48: 503–535.
47. Phibbs B. Marriott H. (1985) Complications of permanent transvenous pacing. N Engl J Med 312: 1428–1432.
48. Pierrotti L. Baddour L. (2002) Fungal endocarditis, 1995–2000. Chest 122: 302–310.
49. Rallidis L. Komninos K. Papasteriadis E. (2003) Pacemaker-related endocarditis: the value of transoesophageal echocardiography in diagnosis and treatment. Acta Cardiol 58: 31–34.
50. Roger P. Boissy C. Gari-Toussaint M. Foucher R. Mondain V. Vandenbos F. et al. (2000) Medical treatment of a pacemaker endocarditis due to Candida albicans and to Candida glabrata. J Infect 41: 176–178.
51. Ruttmann E. Hangler H. Kilo J. Hofer D. Muller L. Hintringer F. et al. (2006) Transvenous pacemaker lead removal is safe and effective even in large vegetations: an analysis of 53 cases of pacemaker lead endocarditis. Pacing Clin Electrophysiol 29: 231–236.
52. Schulze M. Ostermaier R. Franke Y. Matschke K. Braun M. Strasser R. (2005) Images in cardiovascular medicine. aortic endocarditis caused by inadvertent left ventricular pacemaker lead placement. Circulation 112: e361–e363.
53. Smith P. Vidaillet H. Hayes J. Wethington P. Stahl L. Hull M. et al. (1998) Infections with nonthoracotomy implantable cardioverter defibrillators: can these be prevented? Endotak Lead Clinical Investigators. Pacing Clin Electrophysiol 21: 42–55.
54. Sohail M. Khan A. Freidman P. (2005) Electrophysiologic Cardiac Device Infections: Risk Factor Analysis Using a Case-Control Study. San Francisco, CA: Infectious Diseases Society of America.
55. Sohail M. Uslan D. Khan A. Friedman P. Hayes D. Wilson W. et al. (2008) Infective endocarditis complicating permanent pacemaker and implantable cardioverter-defibrillator infection. Mayo Clin Proc 83: 46–53.
56. Sohail M. Uslan D. Khan A. Friedman P. Hayes D. Wilson W. et al. (2007 a) Management and outcome of permanent pacemaker and implantable cardioverter-defibrillator infections. J Am Coll Cardiol 49: 1851–1859.
57. Sohail M. Uslan D. Khan A. Friedman P. Hayes D. Wilson W. et al. (2007 b) Risk factor analysis of permanent pacemaker infection. Clin Infect Dis 45: 166–173.
58. Talarmin J. Boutoille D. Tattevin P. Abgueguen P. Ansart S. Roblot F. et al. (2009) Candida endocarditis: role of new antifungal agents. Mycoses 52: 60–66.
59. Uslan D. Sohail M. St Sauver J. Friedman P. Hayes D. Stoner S. et al. (2007) Permanent pacemaker and implantable cardioverter defibrillator infection: a population-based study. Arch Intern Med 167: 669–675.
60. Victor F. de Place C. Camus C. Le Breton H. Leclercq C. Pavin D. et al. (1999) Pacemaker lead infection: echocardiographic features, management, and outcome. Heart 81: 82–87.
61. Voet J. Vandekerckhove Y. Muyldermans L. Missault L. Matthys L. (1999) Pacemaker lead infection: report of three cases and review of the literature. Heart 81: 88–91.
62. Wilson H. Jr Downes T. Julian J. White W. Haponik E. (1993) Candida endocarditis. A treatable form of pacemaker infection. Chest 103: 283–284.