Site-specific mutation of the sensor kinase gras in Staphylococcus aureus alters the adaptive response to distinct cationic antimicrobial peptides

Infection and Immunity

Volumn 82, Issue 12, 2014, Pages 5336-5345

  Cheung, Ambrose L ^a   Bayer, Arnold S ^b,c   Yeaman, Michael R ^b,c   Xiong, Yan Q ^b,c   Waring, Alan J ^b,c   Memmi, Guido ^a   Donegan, Niles ^a   Chaili, Siyang ^b   Yang, Soo Jin ^b,c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b HARBOR UCLA MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; DAPTOMYCIN; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE GRAS; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; RNA; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL PROTEIN; MUTANT PROTEIN; PROTEIN KINASE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENETICS; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CELL SURFACE; COLONY FORMING UNIT; CONTROLLED STUDY; EXPERIMENTAL RABBIT; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOST RESISTANCE; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OPEN READING FRAME; SITE DIRECTED MUTAGENESIS; UPREGULATION; ANIMAL; DISEASE MODEL; DRUG EFFECTS; ENDOCARDITIS; FEMALE; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; RABBIT;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; ENDOCARDITIS; FEMALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PROTEIN KINASES; RABBITS; SEQUENCE DELETION; STRESS, PHYSIOLOGICAL;

EID: 84911421857     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.02480-14     Document Type: Article

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