Disruption of both nesprin 1 and desmin results in nuclear anchorage defects and fibrosis in skeletal muscle

Human Molecular Genetics

Volumn 23, Issue 22, 2014, Pages 5879-5892

  Chapman, Mark A ^a   Zhang, Jianlin ^a   Banerjee, Indroneal ^a   Guo, Ling T ^c   Zhang, Zhiwei ^d   Shelton, G Diane ^c   Ouyang, Kunfu ^a,e   Lieber, Richard L ^b,c   Chen, Ju ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CENTRAL SOUTH UNIVERSITY   (China)

^e PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETON PROTEIN; DESMIN; HETEROCHROMATIN PROTEIN 1; HETEROCHROMATIN PROTEIN 1BETA; MEMBRANE PROTEIN; NESPRIN 1; UNCLASSIFIED DRUG; NERVE PROTEIN; NUCLEAR PROTEIN; SYNE1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL ANCHORAGE; CELL FUNCTION; CELL LOSS; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; GENE DISRUPTION; IMMUNOFLUORESCENCE TEST; KNOCKOUT MOUSE; KYPHOSIS; LIFESPAN; MECHANOTRANSDUCTION; MORTALITY; MOUSE; MUSCLE RIGIDITY; MUSCLE STRENGTH; MUSCULOSKELETAL SYSTEM PARAMETERS; MYOFIBROSIS; NONHUMAN; NUCLEAR SHAPE; PROTEIN CROSS LINKING; PROTEIN MODIFICATION; QUANTITATIVE ANALYSIS; SKELETAL MUSCLE; SURVIVAL RATE; TRANSMISSION ELECTRON MICROSCOPY; WILD TYPE; ANIMAL; CELL NUCLEUS; FEMALE; FIBROSIS; GENETICS; HUMAN; MALE; METABOLISM; MUSCULAR DYSTROPHY; PATHOLOGY; PROTEIN TRANSPORT;

ANIMALS; CELL NUCLEUS; DESMIN; FEMALE; FIBROSIS; HUMANS; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEIN TRANSPORT;

EID: 84911394363     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu310     Document Type: Article

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