메뉴 건너뛰기




Volumn 110, Issue 8, 2014, Pages 952-959

Stromal MicroRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer

Author keywords

5 fluorouracil; Biomarkers; MicroRNA 21; Pancreatic cancer

Indexed keywords

BIOLOGICAL MARKER; FLUOROURACIL; GEMCITABINE; MICRORNA 21; ANTINEOPLASTIC ANTIMETABOLITE; MICRORNA; MIRN21 MICRORNA, HUMAN;

EID: 84911002296     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.23750     Document Type: Article
Times cited : (45)

References (40)
  • 1
    • 84911005810 scopus 로고    scopus 로고
    • Cancer Facts & Figures 2013In Society AC (ed). Atlanta American Cancer Society
    • Cancer Facts & Figures 2013. In Society AC (ed). Atlanta: American Cancer Society 2013.
    • (2013)
  • 2
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA 3rd, Moore MJ, Andersen J, et al.: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J Clin Oncol 1997;15:2403-2413.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Andersen, J.3
  • 3
    • 33846405332 scopus 로고    scopus 로고
    • Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: A randomized controlled trial
    • Oettle H, Post S, Neuhaus P, et al.: Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: A randomized controlled trial. JAMA 2007;297:267-277.
    • (2007) JAMA , vol.297 , pp. 267-277
    • Oettle, H.1    Post, S.2    Neuhaus, P.3
  • 4
    • 34047216068 scopus 로고    scopus 로고
    • Review. Molecular background of chemoresistance in pancreatic cancer
    • Zalatnai A, Molnar J: Review. Molecular background of chemoresistance in pancreatic cancer. In Vivo 2007;21:339-347.
    • (2007) Vivo , vol.21 , pp. 339-347
    • Zalatnai, A.1    Molnar, J.2
  • 5
    • 84865080615 scopus 로고    scopus 로고
    • The pancreas cancer microenvironment
    • Feig C, Gopinathan A, Neesse A, et al.: The pancreas cancer microenvironment. Clin Cancer Res 2012;18:4266-4276.
    • (2012) Clin Cancer Res , vol.18 , pp. 4266-4276
    • Feig, C.1    Gopinathan, A.2    Neesse, A.3
  • 7
    • 3042655528 scopus 로고    scopus 로고
    • Membrane transporters and channels: Role of the transportome in cancer chemosensitivity and chemoresistance
    • Huang Y, Anderle P, Bussey KJ, et al.: Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance. Cancer Res 2004;64:4294-4301.
    • (2004) Cancer Res , vol.64 , pp. 4294-4301
    • Huang, Y.1    Anderle, P.2    Bussey, K.J.3
  • 8
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NFκB
    • Wang CY, Cusack JC Jr., Liu R, Baldwin AS Jr.: Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NFκB. Nat Med 1999;5:412-417.
    • (1999) Nat Med , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack, J.C.2    Liu, R.3    Baldwin, A.S.4
  • 9
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman MM: Mechanisms of cancer drug resistance. Annu Rev Med 2002;53:615-627.
    • (2002) Annu Rev Med , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 10
    • 84872611820 scopus 로고    scopus 로고
    • Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer
    • Provenzano PP, Hingorani SR: Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer. Br J Cancer 2013;108: 1-8.
    • (2013) Br J Cancer , vol.108 , pp. 1-8
    • Provenzano, P.P.1    Hingorani, S.R.2
  • 11
    • 78650491562 scopus 로고    scopus 로고
    • Resistance may not be futile: MicroRNA biomarkers for chemoresistance and potential therapeutics
    • Allen KE, Weiss GJ: Resistance may not be futile: MicroRNA biomarkers for chemoresistance and potential therapeutics. Mol Cancer Ther 2010;9:3126-3136.
    • (2010) Mol Cancer Ther , vol.9 , pp. 3126-3136
    • Allen, K.E.1    Weiss, G.J.2
  • 12
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y, et al.: A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005;65:9628-9632.
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 13
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova DA, et al.: MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008;27:2128-2136.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3
  • 14
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J, Weinberg RA: Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007;449:682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 15
    • 84877698814 scopus 로고    scopus 로고
    • MicroRNA-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas
    • Wang YQ, Guo RD, Guo RM, et al.: MicroRNA-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas. J Cell Biochem 2013;114:1464-1473.
    • (2013) J Cell Biochem , vol.114 , pp. 1464-1473
    • Wang, Y.Q.1    Guo, R.D.2    Guo, R.M.3
  • 16
    • 84879177004 scopus 로고    scopus 로고
    • MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11
    • Bockhorn J, Dalton R, Nwachukwu C, et al.: MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat Commun 2013;4:1393.
    • (2013) Nat Commun , vol.4 , pp. 1393
    • Bockhorn, J.1    Dalton, R.2    Nwachukwu, C.3
  • 17
    • 84878986540 scopus 로고    scopus 로고
    • A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis
    • Vecchione A, Belletti B, Lovat F, et al.: A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis. Proc Natl Acad Sci U S A 2013;110:9845-9850.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 9845-9850
    • Vecchione, A.1    Belletti, B.2    Lovat, F.3
  • 18
    • 84872496432 scopus 로고    scopus 로고
    • MicroRNAs as potential biomarkers in human solid tumors
    • Shen J, Stass SA, Jiang F: MicroRNAs as potential biomarkers in human solid tumors. Cancer Lett 2013;329:125-136.
    • (2013) Cancer Lett , vol.329 , pp. 125-136
    • Shen, J.1    Stass, S.A.2    Jiang, F.3
  • 19
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • Kota J, Chivukula RR, O'Donnell KA, et al.: Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009;137:1005-1017.
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.R.2    O'Donnell, K.A.3
  • 20
    • 84878858306 scopus 로고    scopus 로고
    • Therapeutic delivery of microRNA-29b by cationic lipoplexes for lung cancer
    • Wu Y, Crawford M, Mao Y, et al.: Therapeutic delivery of microRNA-29b by cationic lipoplexes for lung cancer. Mol Ther Nucleic Acids 2013;2:e84.
    • (2013) Mol Ther Nucleic Acids , vol.2 , pp. e84
    • Wu, Y.1    Crawford, M.2    Mao, Y.3
  • 21
    • 77950560584 scopus 로고    scopus 로고
    • MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions
    • du Rieu MC, Torrisani J, Selves J, et al.: MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions. Clin Chem 2010;56:603-612.
    • (2010) Clin Chem , vol.56 , pp. 603-612
    • Du Rieu, M.C.1    Torrisani, J.2    Selves, J.3
  • 22
    • 57049090610 scopus 로고    scopus 로고
    • MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival
    • Dillhoff M, Liu J, Frankel W, et al.: MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival. J Gastrointest Surg 2008;12:2171-2176.
    • (2008) J Gastrointest Surg , vol.12 , pp. 2171-2176
    • Dillhoff, M.1    Liu, J.2    Frankel, W.3
  • 23
    • 84882749158 scopus 로고    scopus 로고
    • MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis
    • Kadera BE, Li L, Toste PA, et al.: MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis. PLoS One 2013;8:e71978.
    • (2013) PLoS One , vol.8 , pp. e71978
    • Kadera, B.E.1    Li, L.2    Toste, P.A.3
  • 24
    • 77956296766 scopus 로고    scopus 로고
    • Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer
    • Hwang JH, Voortman J, Giovannetti E, et al.: Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer. PLoS One 2010;5:e10630.
    • (2010) PLoS One , vol.5 , pp. e10630
    • Hwang, J.H.1    Voortman, J.2    Giovannetti, E.3
  • 25
    • 77953169001 scopus 로고    scopus 로고
    • MicroRNA-21 in pancreatic cancer: Correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity
    • Giovannetti E, Funel N, Peters GJ, et al.: MicroRNA-21 in pancreatic cancer: Correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity. Cancer Res 2010;70:4528-4538.
    • (2010) Cancer Res , vol.70 , pp. 4528-4538
    • Giovannetti, E.1    Funel, N.2    Peters, G.J.3
  • 26
    • 78650500590 scopus 로고    scopus 로고
    • MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2
    • Valeri N, Gasparini P, Braconi C, et al.: MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2). Proc Natl Acad Sci U S A 2010;107: 21098-21103.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 21098-21103
    • Valeri, N.1    Gasparini, P.2    Braconi, C.3
  • 27
    • 78149469070 scopus 로고    scopus 로고
    • MicroRNA-21 induces resistance to the anti-tumour effect of interferon-alpha/5-fluorouracil in hepatocellular carcinoma cells
    • Tomimaru Y, Eguchi H, Nagano H, et al.: MicroRNA-21 induces resistance to the anti-tumour effect of interferon-alpha/5-fluorouracil in hepatocellular carcinoma cells. Br J Cancer 2010;103:1617-1626.
    • (2010) Br J Cancer , vol.103 , pp. 1617-1626
    • Tomimaru, Y.1    Eguchi, H.2    Nagano, H.3
  • 28
    • 79955841030 scopus 로고    scopus 로고
    • Fluorouracil-based chemoradiation with either gemcitabine or fluorouracil chemotherapy after resection of pancreatic adenocarcinoma: 5'year analysis of the U.S. Intergroup/RTOG 9704 phase III trial
    • Regine WF, Winter KA, Abrams R, et al.: Fluorouracil-based chemoradiation with either gemcitabine or fluorouracil chemotherapy after resection of pancreatic adenocarcinoma: 5-year analysis of the U.S. Intergroup/RTOG 9704 phase III trial. Ann Surg Oncol 2011;18:1319-1326.
    • (2011) Ann Surg Oncol , vol.18 , pp. 1319-1326
    • Regine, W.F.1    Winter, K.A.2    Abrams, R.3
  • 29
    • 84871157346 scopus 로고    scopus 로고
    • Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
    • Jacobetz MA, Chan DS, Neesse A, et al.: Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut 2013;62:112-120.
    • (2013) Gut , vol.62 , pp. 112-120
    • Jacobetz, M.A.1    Chan, D.S.2    Neesse, A.3
  • 30
    • 38049115129 scopus 로고    scopus 로고
    • Endogenous human microRNAs that suppress breast cancer metastasis
    • Tavazoie SF, Alarcon C, Oskarsson T, et al.: Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008;451:147-152.
    • (2008) Nature , vol.451 , pp. 147-152
    • Tavazoie, S.F.1    Alarcon, C.2    Oskarsson, T.3
  • 31
    • 84883818845 scopus 로고    scopus 로고
    • Expression, tissue distribution and function of miR-21 in esophageal squamous cell carcinoma
    • Nouraee N, Van Roosbroeck K, Vasei M, et al.: Expression, tissue distribution and function of miR'21 in esophageal squamous cell carcinoma. PLoS One 2013;8:e73009.
    • (2013) PLoS One , vol.8 , pp. e73009
    • Nouraee, N.1    Van Roosbroeck, K.2    Vasei, M.3
  • 32
    • 55549120234 scopus 로고    scopus 로고
    • MicroRNA miR'21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • Yan LX, Huang XF, Shao Q, et al.: MicroRNA miR'21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 2008;14:2348-2360.
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.X.1    Huang, X.F.2    Shao, Q.3
  • 33
    • 38749089854 scopus 로고    scopus 로고
    • MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
    • Schetter AJ, Leung SY, Sohn JJ, et al.: MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008;299:425-436.
    • (2008) JAMA , vol.299 , pp. 425-436
    • Schetter, A.J.1    Leung, S.Y.2    Sohn, J.J.3
  • 34
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA'21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, et al.: MicroRNA'21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007;133:647-658.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3
  • 35
    • 66849124564 scopus 로고    scopus 로고
    • MicroRNA'21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance
    • Moriyama T, Ohuchida K, Mizumoto K, et al.: MicroRNA'21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance. Mol Cancer Ther 2009;8:1067-1074.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1067-1074
    • Moriyama, T.1    Ohuchida, K.2    Mizumoto, K.3
  • 36
    • 40449113435 scopus 로고    scopus 로고
    • Fluorouracil vs. Gemcitabine chemotherapy before and after fluorouracilbased chemoradiation following resection of pancreatic adenocarcinoma: A randomized controlled trial
    • Regine WF, Winter KA, Abrams RA, et al.: Fluorouracil vs. gemcitabine chemotherapy before and after fluorouracilbased chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial. JAMA 2008;299: 1019-1026.
    • (2008) JAMA , vol.299 , pp. 1019-1026
    • Regine, W.F.1    Winter, K.A.2    Abrams, R.A.3
  • 37
    • 84875226059 scopus 로고    scopus 로고
    • Pancreatic ductal adenocarcinoma: Is there a survival difference for R1 resections versus locally advanced unresectable tumors- What is a true"R0 resection?
    • Konstantinidis IT, Warshaw AL, Allen JN, et al.: Pancreatic ductal adenocarcinoma: is there a survival difference for R1 resections versus locally advanced unresectable tumors- What is a "true" R0 resection- Ann Surg 2013;257:731-736.
    • (2013) Ann Surg , vol.257 , pp. 731-736
    • Konstantinidis, I.T.1    Warshaw, A.L.2    Allen, J.N.3
  • 38
    • 84866863598 scopus 로고    scopus 로고
    • The prognostic importance of miR'21 in stage II colon cancer: A population-based study
    • Kjaer-Frifeldt S, Hansen TF, Nielsen BS, et al.: The prognostic importance of miR'21 in stage II colon cancer: A population-based study. Br J Cancer 2012;107:1169-1174.
    • (2012) Br J Cancer , vol.107 , pp. 1169-1174
    • Kjaer-Frifeldt, S.1    Hansen, T.F.2    Nielsen, B.S.3
  • 39
    • 79951671912 scopus 로고    scopus 로고
    • High levels of MicroRNA'21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patients
    • Nielsen BS, Jorgensen S, Fog JU, et al.: High levels of MicroRNA'21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patients. Clin Exp Metastasis 2011;28:27-38.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 27-38
    • Nielsen, B.S.1    Jorgensen, S.2    Fog, J.U.3
  • 40
    • 84876786403 scopus 로고    scopus 로고
    • Astarring role for stellate cells in the pancreatic cancer microenvironment
    • Apte MV, Wilson JS, Lugea A, Pandol SJ:Astarring role for stellate cells in the pancreatic cancer microenvironment. Gastroenterology 2013;144:1210-1219.
    • (2013) Gastroenterology , vol.144 , pp. 1210-1219
    • Apte, M.V.1    Wilson, J.S.2    Lugea, A.3    Pandol, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.