Nef proteins of epidemic HIV-1 group O strains antagonize human tetherin

Cell Host and Microbe

Volumn 16, Issue 5, 2014, Pages 639-650

  Kluge, Silvia F ^a   Mack, Katharina ^a   Iyer, Shilpa S ^b   Pujol, François M ^c   Heigele, Anke ^a   Learn, Gerald H ^b   Usmani, Shariq M ^a   Sauter, Daniel ^a   Joas, Simone ^a   Hotter, Dominik ^a   Bibollet Ruche, Frederic ^b   Plenderleith, Lindsey J ^d   Peeters, Martine ^e   Geyer, Matthias ^f   Sharp, Paul M ^d   Fackler, Oliver T ^c   Hahn, Beatrice H ^b   Kirchhoff, Frank ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIV MONTPELLIER   (France)

^f CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCH CAESAR   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; HOST FACTOR; NEF PROTEIN; TETHERIN; UNCLASSIFIED DRUG; VPU PROTEIN; BST2 PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LEUKOCYTE ANTIGEN;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; EPIDEMIC; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; VIRION; VIRUS RESISTANCE; VIRUS STRAIN; VIRUS TRANSMISSION; ZOONOSIS; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CD4+ T LYMPHOCYTE; CLASSIFICATION; ENDOCYTOSIS; GENE DELETION; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PATHOGENICITY; PROTEIN CONFORMATION; SEQUENCE ANALYSIS; TUMOR CELL LINE; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; ANTIGENS, CD; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; ENDOCYTOSIS; EVOLUTION, MOLECULAR; GPI-LINKED PROTEINS; HEK293 CELLS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PROTEIN CONFORMATION; SEQUENCE ANALYSIS; SEQUENCE DELETION; VIRION;

EID: 84910631057     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2014.10.002     Document Type: Article

References (35)

1. L.J. Cocka, and P. Bates Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities PLoS Pathog. 8 2012 e1002931
2. C. Delaugerre, F. De Oliveira, C. Lascoux-Combe, J.C. Plantier, and F. Simon HIV-1 group N: travelling beyond Cameroon Lancet 378 2011 1894
3. A.E. Fenton-May, O. Dibben, T. Emmerich, H. Ding, K. Pfafferott, M.M. Aasa-Chapman, P. Pellegrino, I. Williams, M.S. Cohen, and F. Gao Relative resistance of HIV-1 founder viruses to control by interferon-alpha Retrovirology 10 2013 146
4. J.F. Fortin, C. Barat, Y. Beauséjour, B. Barbeau, and M.J. Tremblay Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction J. Biol. Chem. 279 2004 39520 39531
5. R.P. Galão, A. Le Tortorec, S. Pickering, T. Kueck, and S.J. Neil Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses Cell Host Microbe 12 2012 633 644
6. N. Götz, D. Sauter, S.M. Usmani, J.V. Fritz, C. Goffinet, A. Heigele, M. Geyer, F. Bibollet-Ruche, G.H. Learn, and O.T. Fackler Reacquisition of Nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee host Cell Host Microbe 12 2012 373 380
7. R.K. Gupta, and G.J. Towers A tail of Tetherin: how pandemic HIV-1 conquered the world Cell Host Microbe 6 2009 393 395
8. R.K. Gupta, P. Mlcochova, A. Pelchen-Matthews, S.J. Petit, G. Mattiuzzo, D. Pillay, Y. Takeuchi, M. Marsh, and G.J. Towers Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration Proc. Natl. Acad. Sci. USA 106 2009 20889 20894
9. B. Jia, R. Serra-Moreno, W. Neidermyer, A. Rahmberg, J. Mackey, I.B. Fofana, W.E. Johnson, S. Westmoreland, and D.T. Evans Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2 PLoS Pathog. 5 2009 e1000429
10. X. Jia, E. Weber, A. Tokarev, M. Lewinski, M. Rizk, M. Suarez, J. Guatelli, and Y. Xiong Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1 Elife 3 2014 e02362
11. P. Lemey, O.G. Pybus, A. Rambaut, A.J. Drummond, D.L. Robertson, P. Roques, M. Worobey, and A.M. Vandamme The molecular population genetics of HIV-1 group O Genetics 167 2004 1059 1068
12. R.A. Liberatore, and P.D. Bieniasz Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo Proc. Natl. Acad. Sci. USA 108 2011 18097 18101
13. T. Mourez, F. Simon, and J.C. Plantier Non-M variants of human immunodeficiency virus type 1 Clin. Microbiol. Rev. 26 2013 448 461
14. S.J. Neil, V. Sandrin, W.I. Sundquist, and P.D. Bieniasz An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein Cell Host Microbe 2 2007 193 203
15. S.J.D. Neil, T. Zang, and P.D. Bieniasz Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu Nature 451 2008 425 430
16. N.F. Parrish, F. Gao, H. Li, E.E. Giorgi, H.J. Barbian, E.H. Parrish, L. Zajic, S.S. Iyer, J.M. Decker, and A. Kumar Phenotypic properties of transmitted founder HIV-1 Proc. Natl. Acad. Sci. USA 110 2013 6626 6633
17. S.J. Petit, C. Blondeau, and G.J. Towers Analysis of the human immunodeficiency virus type 1 M group Vpu domains involved in antagonizing tetherin J. Gen. Virol. 92 2011 2937 2948
18. J.C. Plantier, M. Leoz, J.E. Dickerson, F. De Oliveira, F. Cordonnier, V. Lemée, F. Damond, D.L. Robertson, and F. Simon A new human immunodeficiency virus derived from gorillas Nat. Med. 15 2009 871 872
19. D. Sauter, M. Schindler, A. Specht, W.N. Landford, J. Münch, K.-A. Kim, J. Votteler, U. Schubert, F. Bibollet-Ruche, and B.F. Keele Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains Cell Host Microbe 6 2009 409 421
20. D. Sauter, A. Specht, and F. Kirchhoff Tetherin: holding on and letting go Cell 141 2010 392 398
21. D. Sauter, S. Hué, S.J. Petit, J.-C. Plantier, G.J. Towers, F. Kirchhoff, and R.K. Gupta HIV-1 group P is unable to antagonize human tetherin by Vpu, Env or Nef Retrovirology 8 2011 103
22. D. Sauter, D. Unterweger, M. Vogl, S.M. Usmani, A. Heigele, S.F. Kluge, E. Hermkes, M. Moll, E. Barker, and M. Peeters Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein PLoS Pathog. 8 2012 e1003093
23. M. Schindler, J. Münch, O. Kutsch, H. Li, M.L. Santiago, F. Bibollet-Ruche, M.C. Müller-Trutwin, F.J. Novembre, M. Peeters, and V. Courgnaud Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1 Cell 125 2006 1055 1067
24. S. Schmidt, J.V. Fritz, J. Bitzegeio, O.T. Fackler, and O.T. Keppler HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction MBio 2 2011 e00036-e11
25. R. Serra-Moreno, K. Zimmermann, L.J. Stern, and D.T. Evans Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis PLoS Pathog. 9 2013 e1003487
26. P.M. Sharp, and B.H. Hahn Origins of HIV and the AIDS pandemic Cold Spring Harb. Perspect. Med. 1 2011 a006841
27. D.M. Tebit, L. Zekeng, L. Kaptué, L. Gürtler, O.T. Fackler, O.T. Keppler, O. Herchenröder, and H.G. Kräusslich Construction and characterization of an HIV-1 group O infectious molecular clone and analysis of vpr- and nef-negative derivatives Virology 326 2004 329 339
28. A. Vallari, V. Holzmayer, B. Harris, J. Yamaguchi, C. Ngansop, F. Makamche, D. Mbanya, L. Kaptué, N. Ndembi, and L. Gürtler Confirmation of putative HIV-1 group P in Cameroon J. Virol. 85 2011 1403 1407
29. N. Van Damme, D. Goff, C. Katsura, R.L. Jorgenson, R. Mitchell, M.C. Johnson, E.B. Stephens, and J. Guatelli The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein Cell Host Microbe 3 2008 245 252
30. A. Vessière, D. Rousset, A. Kfutwah, M. Leoz, A. Depatureaux, F. Simon, and J.C. Plantier Diagnosis and monitoring of HIV-1 group O-infected patients in Cameroun J. Acquir. Immune Defic. Syndr. 53 2010 107 110
31. R. Vigan, and S.J. Neil Separable determinants of subcellular localization and interaction account for the inability of group O HIV-1 Vpu to counteract tetherin J. Virol. 85 2011 9737 9748
32. S.J. Yang, L.A. Lopez, H. Hauser, C.M. Exline, K.G. Haworth, and P.M. Cannon Anti-tetherin activities in Vpu-expressing primate lentiviruses Retrovirology 7 2010 13
33. S.J. Yang, L.A. Lopez, C.M. Exline, K.G. Haworth, and P.M. Cannon Lack of adaptation to human tetherin in HIV-1 group O and P Retrovirology 8 2011 78
34. F. Zhang, S.J. Wilson, W.C. Landford, B. Virgen, D. Gregory, M.C. Johnson, J. Munch, F. Kirchhoff, P.D. Bieniasz, and T. Hatziioannou Nef proteins from simian immunodeficiency viruses are tetherin antagonists Cell Host Microbe 6 2009 54 67
35. F. Zhang, W.N. Landford, M. Ng, M.W. McNatt, P.D. Bieniasz, and T. Hatziioannou SIV Nef proteins recruit the AP-2 complex to antagonize Tetherin and facilitate virion release PLoS Pathog. 7 2011 e1002039